AutismKB 2.0

Annotation Detail for SIN3A


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Basic Information Top
Gene Symbol:SIN3A ( DKFZp434K2235,FLJ90319,KIAA0700 )
Gene Full Name: SIN3 homolog A, transcription regulator (yeast)
Band: 15q24.2
Quick LinksEntrez ID:25942; OMIM: 607776; Uniprot ID:SIN3A_HUMAN; ENSEMBL ID: ENSG00000169375; HGNC ID: 19353
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst6 / 6231996
fetus23 / 56401240
neonate1 / 3109732
infant0 / 236200 
juvenile3 / 5555653
adult117 / 193912160
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor18 / 94178191
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor15 / 114246131
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor28 / 263845106
glioma2 / 10688318
head and neck tumor14 / 136302102
kidney tumor6 / 6895987
leukemia4 / 9584241
liver tumor6 / 9635962
lung tumor1 / 1031279
lymphoma6 / 7175583
non-neoplasia2 / 9725020
normal139 / 336030741
ovarian tumor5 / 7668265
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer1 / 1026809
retinoblastoma9 / 46356194
skin tumor12 / 12494996
soft tissue/muscle tissue tumor16 / 125191127
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites3 / 4001574
bladder1 / 2975733
blood5 / 12347840
bone1 / 7165513
bone marrow7 / 48801143
brain39 / 110098935
cervix2 / 4817141
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue17 / 21572278
esophagus0 / 202090 
eye17 / 21105480
heart2 / 8962622
intestine16 / 23447268
kidney12 / 21177756
larynx0 / 241450 
liver7 / 20774333
lung16 / 33697447
lymph3 / 4427067
lymph node9 / 9161098
mammary gland19 / 153271123
mouth9 / 67052134
muscle7 / 10771564
nerve0 / 157680 
ovary8 / 10205178
pancreas9 / 21481241
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta17 / 28082560
prostate3 / 18934515
salivary gland3 / 20155148
skin13 / 21057461
spleen5 / 5395292
stomach0 / 966190 
testis29 / 33044287
thymus3 / 8113136
thyroid4 / 4747384
tonsil1 / 1699958
trachea7 / 52413133
umbilical cord0 / 136800 
uterus17 / 23287872
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P304760
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.09 ± 0.59
Basal Forebrain4.75 ± 0.52
Basal Part of Pons4.41 ± 0.42
Cerebellar Cortex4.88 ± 0.38
Cerebellar Nuclei4.13 ± 0.44
Claustrum5.13 ± 0.72
Epithalamus4.97 ± 0.29
Frontal Lobe4.52 ± 0.47
Globus Pallidus3.98 ± 0.5
Hypothalamus4.76 ± 0.35
Insula4.73 ± 0.47
Limbic Lobe4.85 ± 0.43
Mesencephalon4.66 ± 0.43
Myelencephalon4.71 ± 0.51
Occipital Lobe4.72 ± 0.42
Parietal Lobe4.57 ± 0.52
Pontine Tegmentum4.52 ± 0.55
Striatum4.56 ± 0.39
Subthalamus4.12 ± 0.46
Temporal Lobe4.77 ± 0.45
Thalamus4.4 ± 0.52
White Matter3.49 ± 0.86
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sin3aCBCerebellum0
0
Sin3aCTXCerebral cortex0
0
Sin3aHIPHippocampal region0
0
Sin3aHPFHippocampal formation0
0
Sin3aHYHypothalamus0
0
Sin3aLSXLateral septal complex0
0
Sin3aMBMidbrain0
0
Sin3aMYMedulla0
0
Sin3aOLFOlfactory bulb0
0
Sin3aPPons0
0
Sin3aPALPallidum0
0
Sin3aRHPRetrohippocampal region0
0
Sin3asAMYStriatum-like amygdalar nuclei0
0
Sin3aSTRStriatum0
0
Sin3aSTRdStriatum dorsal region0
0
Sin3aSTRvStriatum ventral region0
0
Sin3aTHThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00042879 14 1155 1168 TMENVDSLDKLECR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018