AutismKB 2.0

Annotation Detail for GANC


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GANC ( MGC138256 )
Gene Full Name: glucosidase, alpha; neutral C
Band: 15q15.1
Quick LinksEntrez ID:2595; OMIM: 104180; Uniprot ID:GANC_HUMAN; ENSEMBL ID: ENSG00000214013; HGNC ID: 4139
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_818_PI416379584
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.59 ± 0.75
Basal Forebrain3.45 ± 0.51
Basal Part of Pons4.09 ± 0.45
Cerebellar Cortex4.05 ± 0.3
Cerebellar Nuclei3.95 ± 0.75
Claustrum3.27 ± 0.76
Epithalamus3.53 ± 0.71
Frontal Lobe3.52 ± 0.63
Globus Pallidus4.14 ± 0.56
Hypothalamus3.34 ± 0.61
Insula3.4 ± 0.46
Limbic Lobe3.34 ± 0.48
Mesencephalon3.8 ± 0.74
Myelencephalon3.55 ± 0.67
Occipital Lobe3.97 ± 0.53
Parietal Lobe3.59 ± 0.64
Pontine Tegmentum3.56 ± 0.57
Striatum3.41 ± 0.61
Subthalamus3.54 ± 0.21
Temporal Lobe3.6 ± 0.54
Thalamus3.69 ± 0.54
White Matter5.3 ± 0.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
GancCBCerebellum5.94
7.15
GancCTXCerebral cortex5.58
4.23
GancHIPHippocampal region3.83
3.49
GancHPFHippocampal formation4.02
3.44
GancHYHypothalamus0.75
0.6
GancLSXLateral septal complex0.52
0.64
GancMBMidbrain2.91
2.79
GancMYMedulla6.42
6.62
GancOLFOlfactory bulb5.57
5.19
GancPPons5.36
5.72
GancPALPallidum1.29
1.07
GancRHPRetrohippocampal region4.43
3.41
GancsAMYStriatum-like amygdalar nuclei0.39
0.29
GancSTRStriatum1.15
0.87
GancSTRdStriatum dorsal region1.14
0.9
GancSTRvStriatum ventral region1.77
1.12
GancTHThalamus2.56
2.17
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018