Annotation Detail for KANK2
Basic Information Top
| Gene Symbol: | KANK2 ( ANKRD25,DKFZp434N161,FLJ20004,KIAA1518,MGC119707,MXRA3,SIP ) |
|---|---|
| Gene Full Name: | KN motif and ankyrin repeat domains 2 |
| Band: | 19p13.2 |
| Quick Links | Entrez ID:25959; OMIM: NA; Uniprot ID:KANK2_HUMAN; ENSEMBL ID: ENSG00000197256; HGNC ID: 29300 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.726146
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 7 / 564012 | 12 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 21 / 1939121 | 10 |  |
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 1 / 564012 | 1 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 0 / 1939121 | 0 | |
| embryoid body | 6 / 70761 | 84 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 36 / 564012 | 63 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 82 / 1939121 | 42 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 40 / 3360307 | 11 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 4 / 125191 | 31 | |
| uterine tumor | 4 / 90257 | 44 | |
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 1 / 3360307 | 0 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 | |
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 | |
| cervical tumor | 2 / 34366 | 58 | |
| chondrosarcoma | 7 / 82823 | 84 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 3 / 119369 | 25 | |
| germ cell tumor | 8 / 263845 | 30 | |
| glioma | 3 / 106883 | 28 | |
| head and neck tumor | 3 / 136302 | 22 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 2 / 95842 | 20 | |
| liver tumor | 1 / 96359 | 10 | |
| lung tumor | 5 / 103127 | 48 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 9 / 97250 | 92 | |
| normal | 163 / 3360307 | 48 | |
| ovarian tumor | 4 / 76682 | 52 | |
| pancreatic tumor | 5 / 104616 | 47 | |
| primitive neuroectodermal tumor of the CNS | 4 / 125680 | 31 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 2 / 46356 | 43 | |
| skin tumor | 9 / 124949 | 72 | |
| soft tissue/muscle tissue tumor | 3 / 125191 | 23 | |
| uterine tumor | 5 / 90257 | 55 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 6 / 1100989 | 5 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 4 / 211054 | 18 | |
| heart | 5 / 89626 | 55 | |
| intestine | 1 / 234472 | 4 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 1 / 207743 | 4 | |
| lung | 6 / 336974 | 17 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 5 / 214812 | 23 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 2 / 280825 | 7 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 7 / 210574 | 33 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 0 / 96619 | 0 | |
| testis | 3 / 330442 | 9 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 6 / 232878 | 25 | |
| vascular | 1 / 51780 | 19 | |
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 0 / 1100989 | 0 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 1 / 336974 | 2 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 0 / 330442 | 0 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 | |
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 7 / 71655 | 97 | |
| bone marrow | 4 / 48801 | 81 | |
| brain | 36 / 1100989 | 32 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 17 / 149255 | 113 | |
| ear | 6 / 16212 | 370 |  |
| embryonic tissue | 6 / 215722 | 27 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 6 / 211054 | 28 | |
| heart | 3 / 89626 | 33 | |
| intestine | 10 / 234472 | 42 | |
| kidney | 12 / 211777 | 56 | |
| larynx | 0 / 24145 | 0 | |
| liver | 3 / 207743 | 14 | |
| lung | 18 / 336974 | 53 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 4 / 91610 | 43 | |
| mammary gland | 3 / 153271 | 19 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 4 / 107715 | 37 | |
| nerve | 2 / 15768 | 126 | |
| ovary | 5 / 102051 | 48 | |
| pancreas | 8 / 214812 | 37 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 2 / 41328 | 48 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 17 / 280825 | 60 | |
| prostate | 5 / 189345 | 26 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 19 / 210574 | 90 | |
| spleen | 2 / 53952 | 37 | |
| stomach | 1 / 96619 | 10 | |
| testis | 17 / 330442 | 51 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 2 / 47473 | 42 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 9 / 52413 | 171 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 49 / 232878 | 210 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 218418_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 9.9 | |
| Adipocyte | 130.9 | |
| AdrenalCortex | 13.85 | |
| Adrenalgland | 12.55 | |
| Amygdala | 7.85 | |
| Appendix | 66.85 | |
| AtrioventricularNode | 9.25 | |
| BDCA4+_DentriticCells | 5.7 | |
| Bonemarrow | 10.15 | |
| BronchialEpithelialCells | 7.25 | |
| CD105+_Endothelial | 70.6 | |
| CD14+_Monocytes | 6.2 | |
| CD19+_BCells(neg._sel.) | 5.75 | |
| CD33+_Myeloid | 7.4 | |
| CD34+ | 14.8 | |
| CD4+_Tcells | 6.2 | |
| CD56+_NKCells | 6.45 | |
| CD71+_EarlyErythroid | 102.95 | |
| CD8+_Tcells | 5.45 | |
| CardiacMyocytes | 22.45 | |
| Caudatenucleus | 7.1 | |
| Cerebellum | 6.35 | |
| CerebellumPeduncles | 8.8 | |
| CiliaryGanglion | 32.35 | |
| CingulateCortex | 8.5 | |
| Colorectaladenocarcinoma | 7.85 | |
| DorsalRootGanglion | 9.9 | |
| FetalThyroid | 39.15 | |
| Fetalbrain | 7.9 | |
| Fetalliver | 7.65 | |
| Fetallung | 106.45 | |
| GlobusPallidus | 5.6 | |
| Heart | 49.7 | |
| Hypothalamus | 8.8 | |
| Kidney | 8.9 | |
| Leukemia_chronicMyelogenousK-562 | 7.5 | |
| Leukemia_promyelocytic-HL-60 | 6.95 | |
| Leukemialymphoblastic(MOLT-4) | 6.35 | |
| Liver | 10.1 | |
| Lung | 149.75 | |
| Lymphnode | 7.25 | |
| Lymphoma_burkitts(Daudi) | 56.6 | |
| Lymphoma_burkitts(Raji) | 10.2 | |
| MedullaOblongata | 6.95 | |
| OccipitalLobe | 6.3 | |
| OlfactoryBulb | 90.35 | |
| Ovary | 66.6 | |
| Pancreas | 8.45 | |
| PancreaticIslet | 15.85 | |
| ParietalLobe | 8.15 | |
| Pituitary | 9.5 | |
| Placenta | 47 | |
| Pons | 7.4 | |
| PrefrontalCortex | 10.15 | |
| Prostate | 74.8 | |
| Salivarygland | 6.9 | |
| SkeletalMuscle | 8.85 | |
| Skin | 8.05 | |
| SmoothMuscle | 34.95 | |
| Spinalcord | 15.6 | |
| SubthalamicNucleus | 7 | |
| SuperiorCervicalGanglion | 14.25 | |
| TemporalLobe | 7.1 | |
| Testis | 12.35 | |
| TestisGermCell | 53 | |
| TestisIntersitial | 7.35 | |
| TestisLeydigCell | 9.25 | |
| TestisSeminiferousTubule | 11.15 | |
| Thalamus | 7.95 | |
| Thymus | 9.5 | |
| Thyroid | 31.8 | |
| Tongue | 7.75 | |
| Tonsil | 7.6 | |
| Trachea | 14.6 | |
| TrigeminalGanglion | 8.35 | |
| Uterus | 277.2 | |
| UterusCorpus | 81.35 | |
| WholeBlood | 8.7 | |
| Wholebrain | 5.75 | |
| colon | 130.65 | |
| pineal_day | 10.74 | |
| pineal_night | 12.58 | |
| retina | 140.65 | |
| small_intestine | 95.4 | |
- Probe name: A_32_P66756
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.21 ± 1.07 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.73 ± 0.2 | |
| Basal Part of Pons | 1.39 ± 0.41 | |
| Cerebellar Cortex | 1.59 ± 0.69 | |
| Cerebellar Nuclei | 2.17 ± 0.93 | |
| Claustrum | 2.66 ± 0.85 | |
| Epithalamus | 2.79 ± 0.89 | |
| Frontal Lobe | 1.61 ± 0.62 | |
| Globus Pallidus | 2.4 ± 0.32 | |
| Hypothalamus | 1.86 ± 0.67 | |
| Insula | 1.8 ± 0.74 | |
| Limbic Lobe | 1.74 ± 0.65 | |
| Mesencephalon | 1.91 ± 0.64 | |
| Myelencephalon | 1.85 ± 0.71 | |
| Occipital Lobe | 1.89 ± 0.63 | |
| Parietal Lobe | 1.81 ± 0.74 | |
| Pontine Tegmentum | 1.85 ± 0.68 | |
| Striatum | 2.04 ± 0.74 | |
| Subthalamus | 1.84 ± 0.62 | |
| Temporal Lobe | 1.71 ± 0.71 | |
| Thalamus | 1.7 ± 0.58 | |
| White Matter | 2.43 ± 0.43 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Ankrd25 | CB | Cerebellum | 60.17 | |
| 60.7 | | |||
| Ankrd25 | CTX | Cerebral cortex | 37.73 | |
| 25.58 | | |||
| Ankrd25 | HIP | Hippocampal region | 34.48 | |
| 26.2 | | |||
| Ankrd25 | HPF | Hippocampal formation | 39.41 | |
| 30.68 | | |||
| Ankrd25 | HY | Hypothalamus | 27 | |
| 18.43 | | |||
| Ankrd25 | LSX | Lateral septal complex | 16.16 | |
| 8.88 | | |||
| Ankrd25 | MB | Midbrain | 21.42 | |
| 17.1 | | |||
| Ankrd25 | MY | Medulla | 44.22 | |
| 40.17 | | |||
| Ankrd25 | OLF | Olfactory bulb | 51.8 | |
| 39.1 | | |||
| Ankrd25 | P | Pons | 30.22 | |
| 25.48 | | |||
| Ankrd25 | PAL | Pallidum | 19.15 | |
| 15.4 | | |||
| Ankrd25 | RHP | Retrohippocampal region | 46.12 | |
| 34.74 | | |||
| Ankrd25 | sAMY | Striatum-like amygdalar nuclei | 26.36 | |
| 15.55 | | |||
| Ankrd25 | STR | Striatum | 18.91 | |
| 11.56 | | |||
| Ankrd25 | STRd | Striatum dorsal region | 14.92 | |
| 9.04 | | |||
| Ankrd25 | STRv | Striatum ventral region | 27.94 | |
| 17.2 | | |||
| Ankrd25 | TH | Thalamus | 30.25 | |
| 22.55 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| KANK2_HUMAN_224 | 19 | 224 | 242 | QLTVQLKSQKFLGHPTAGR | PRIDE |
| KANK2_HUMAN_337 | 16 | 337 | 352 | EVEVVASTAAGAPAQR | PRIDE |
| PAp00616555 | 8 | 302 | 309 | ELQAAQAR | Peptide Atlas |