AutismKB 2.0

Annotation Detail for DHRS7B


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Basic Information Top
Gene Symbol:DHRS7B ( DKFZp566O084,MGC8916,SDR32C1 )
Gene Full Name: dehydrogenase/reductase (SDR family) member 7B
Band: 17p11.2
Quick LinksEntrez ID:25979; OMIM: NA; Uniprot ID:DRS7B_HUMAN; ENSEMBL ID: ENSG00000109016; HGNC ID: 24547
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus9 / 56401215
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult53 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma5 / 8282360
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor0 / 2638450 
glioma5 / 10688346
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor5 / 10312748
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal83 / 336030724
ovarian tumor5 / 7668265
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow1 / 4880120
brain13 / 110098911
cervix1 / 4817120
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye5 / 21105423
heart3 / 8962633
intestine15 / 23447263
kidney8 / 21177737
larynx2 / 2414582
liver4 / 20774319
lung18 / 33697453
lymph0 / 442700 
lymph node4 / 9161043
mammary gland1 / 1532716
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary7 / 10205168
pancreas6 / 21481227
parathyroid5 / 20539243
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta9 / 28082532
prostate7 / 18934536
salivary gland0 / 201550 
skin9 / 21057442
spleen0 / 539520 
stomach1 / 9661910
testis14 / 33044242
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord1 / 1368073
uterus12 / 23287851
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220690_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts13.8
Adipocyte4.6
AdrenalCortex4.35
Adrenalgland3.65
Amygdala4.6
Appendix4.3
AtrioventricularNode3.2
BDCA4+_DentriticCells4.85
Bonemarrow4.2
BronchialEpithelialCells4.45
CD105+_Endothelial20.65
CD14+_Monocytes22.2
CD19+_BCells(neg._sel.)4.65
CD33+_Myeloid9.3
CD34+16.4
CD4+_Tcells4.65
CD56+_NKCells5.25
CD71+_EarlyErythroid10.4
CD8+_Tcells4.25
CardiacMyocytes5.55
Caudatenucleus3.85
Cerebellum3.45
CerebellumPeduncles4.85
CiliaryGanglion2.95
CingulateCortex4.4
Colorectaladenocarcinoma8.3
DorsalRootGanglion3.25
FetalThyroid4.2
Fetalbrain4.25
Fetalliver3.75
Fetallung3.65
GlobusPallidus3.1
Heart5.5
Hypothalamus5
Kidney3.4
Leukemia_chronicMyelogenousK-5623.9
Leukemia_promyelocytic-HL-603.8
Leukemialymphoblastic(MOLT-4)3.45
Liver5.6
Lung6.85
Lymphnode3.7
Lymphoma_burkitts(Daudi)5.45
Lymphoma_burkitts(Raji)5.95
MedullaOblongata3.9
OccipitalLobe3.85
OlfactoryBulb3.45
Ovary2.8
Pancreas3.5
PancreaticIslet4.65
ParietalLobe4.45
Pituitary5
Placenta4.85
Pons4.05
PrefrontalCortex5.45
Prostate10.1
Salivarygland3.4
SkeletalMuscle4.8
Skin3.25
SmoothMuscle4.9
Spinalcord4.6
SubthalamicNucleus3.85
SuperiorCervicalGanglion4.7
TemporalLobe3.85
Testis16.05
TestisGermCell4.55
TestisIntersitial13.85
TestisLeydigCell8.55
TestisSeminiferousTubule6.8
Thalamus4.35
Thymus3.4
Thyroid9.05
Tongue4.15
Tonsil4.15
Trachea3.6
TrigeminalGanglion4.25
Uterus3.6
UterusCorpus3.75
WholeBlood5
Wholebrain11.85
colon4.35
pineal_day5.52
pineal_night5.44
retina20.925
small_intestine4.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P130352
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.39 ± 0.68
Basal Forebrain3.87 ± 0.45
Basal Part of Pons4.76 ± 0.47
Cerebellar Cortex4.53 ± 0.49
Cerebellar Nuclei4.18 ± 0.62
Claustrum4.16 ± 0.68
Epithalamus4.73 ± 0.82
Frontal Lobe4.61 ± 0.52
Globus Pallidus3.99 ± 0.55
Hypothalamus4.67 ± 0.63
Insula4.54 ± 0.48
Limbic Lobe4.11 ± 0.58
Mesencephalon4.31 ± 0.62
Myelencephalon4.34 ± 0.57
Occipital Lobe3.9 ± 0.53
Parietal Lobe4.25 ± 0.55
Pontine Tegmentum4.33 ± 0.53
Striatum3.93 ± 0.55
Subthalamus4.88 ± 0.46
Temporal Lobe4.48 ± 0.59
Thalamus4.4 ± 0.5
White Matter4.07 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dhrs7bCBCerebellum8.39
12.58
Dhrs7bCTXCerebral cortex10.66
7.92
Dhrs7bHIPHippocampal region22.14
23.93
Dhrs7bHPFHippocampal formation15.26
14.91
Dhrs7bHYHypothalamus0.15
0.14
Dhrs7bLSXLateral septal complex0.39
0.95
Dhrs7bMBMidbrain0.72
1.1
Dhrs7bMYMedulla0.65
0.76
Dhrs7bOLFOlfactory bulb7.71
6.86
Dhrs7bPPons0.58
0.92
Dhrs7bPALPallidum1.26
1.15
Dhrs7bRHPRetrohippocampal region7.11
5.54
Dhrs7bsAMYStriatum-like amygdalar nuclei0.69
0.5
Dhrs7bSTRStriatum1.78
1.36
Dhrs7bSTRdStriatum dorsal region1.56
1.22
Dhrs7bSTRvStriatum ventral region4.7
3.13
Dhrs7bTHThalamus1.9
1.87
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00080605 14 162 175 VMETNYFGPVALTK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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