AutismKB 2.0

Annotation Detail for DAK


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Basic Information Top
Gene Symbol:DAK ( DKFZp586B1621,MGC5621,NET45 )
Gene Full Name: dihydroxyacetone kinase 2 homolog (S. cerevisiae)
Band: 11q12.2
Quick LinksEntrez ID:26007; OMIM: NA; Uniprot ID:DHAK_HUMAN; ENSEMBL ID: ENSG00000149476; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst6 / 6231996
fetus7 / 56401212
neonate0 / 310970 
infant2 / 2362084
juvenile6 / 55556107
adult101 / 193912152
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor10 / 94178106
cervical tumor5 / 34366145
chondrosarcoma4 / 8282348
colorectal tumor17 / 114246148
esophageal tumor2 / 17290115
gastrointestinal tumor7 / 11936958
germ cell tumor20 / 26384575
glioma14 / 106883130
head and neck tumor5 / 13630236
kidney tumor3 / 6895943
leukemia6 / 9584262
liver tumor20 / 96359207
lung tumor10 / 10312796
lymphoma37 / 71755515
non-neoplasia7 / 9725071
normal254 / 336030775
ovarian tumor2 / 7668226
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS17 / 125680135
prostate cancer28 / 102680272
retinoblastoma5 / 46356107
skin tumor18 / 124949144
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland5 / 33197150
ascites3 / 4001574
bladder2 / 2975767
blood9 / 12347872
bone1 / 7165513
bone marrow2 / 4880140
brain100 / 110098990
cervix9 / 48171186
connective tissue12 / 14925580
ear0 / 162120 
embryonic tissue17 / 21572278
esophagus2 / 2020998
eye13 / 21105461
heart0 / 896260 
intestine56 / 234472238
kidney24 / 211777113
larynx2 / 2414582
liver31 / 207743149
lung15 / 33697444
lymph31 / 44270700
lymph node1 / 9161010
mammary gland11 / 15327171
mouth2 / 6705229
muscle4 / 10771537
nerve0 / 157680 
ovary2 / 10205119
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta22 / 28082578
prostate39 / 189345205
salivary gland1 / 2015549
skin18 / 21057485
spleen6 / 53952111
stomach5 / 9661951
testis61 / 330442184
thymus7 / 8113186
thyroid3 / 4747363
tonsil2 / 16999117
trachea5 / 5241395
umbilical cord0 / 136800 
uterus11 / 23287847
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218688_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.95
Adipocyte6.95
AdrenalCortex13.8
Adrenalgland114.65
Amygdala7.6
Appendix7.35
AtrioventricularNode5.85
BDCA4+_DentriticCells8.65
Bonemarrow7.25
BronchialEpithelialCells7.35
CD105+_Endothelial7.35
CD14+_Monocytes7.8
CD19+_BCells(neg._sel.)7.55
CD33+_Myeloid10.25
CD34+12.25
CD4+_Tcells8.15
CD56+_NKCells8.9
CD71+_EarlyErythroid6.8
CD8+_Tcells6.95
CardiacMyocytes10.75
Caudatenucleus6.65
Cerebellum5.9
CerebellumPeduncles8.4
CiliaryGanglion6.05
CingulateCortex7.4
Colorectaladenocarcinoma11.8
DorsalRootGanglion5.55
FetalThyroid7.1
Fetalbrain7.5
Fetalliver6.3
Fetallung5.5
GlobusPallidus5.5
Heart9.5
Hypothalamus7.5
Kidney12.6
Leukemia_chronicMyelogenousK-5629.4
Leukemia_promyelocytic-HL-606.6
Leukemialymphoblastic(MOLT-4)5.85
Liver624.55
Lung8.85
Lymphnode6.15
Lymphoma_burkitts(Daudi)9.35
Lymphoma_burkitts(Raji)18.55
MedullaOblongata6.3
OccipitalLobe6.5
OlfactoryBulb5.55
Ovary4.9
Pancreas6
PancreaticIslet7.85
ParietalLobe7.7
Pituitary8.25
Placenta7.1
Pons6.95
PrefrontalCortex8.55
Prostate10.2
Salivarygland5.8
SkeletalMuscle8.65
Skin5.6
SmoothMuscle8.35
Spinalcord7.8
SubthalamicNucleus6.8
SuperiorCervicalGanglion8.1
TemporalLobe6.65
Testis6.5
TestisGermCell6.5
TestisIntersitial7.75
TestisLeydigCell7.4
TestisSeminiferousTubule6.25
Thalamus7.35
Thymus5.7
Thyroid14.95
Tongue7.3
Tonsil7.2
Trachea6.15
TrigeminalGanglion7.25
Uterus5.65
UterusCorpus6.55
WholeBlood7.85
Wholebrain6.45
colon7.25
pineal_day15.72
pineal_night13.86
retina8.875
small_intestine101.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15444_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.49 ± 0.65
Basal Forebrain3.13 ± 0.66
Basal Part of Pons3.47 ± 0.64
Cerebellar Cortex3.63 ± 0.55
Cerebellar Nuclei2.88 ± 0.57
Claustrum3.32 ± 0.6
Epithalamus3.26 ± 0.62
Frontal Lobe3.26 ± 0.63
Globus Pallidus3.64 ± 0.75
Hypothalamus3.11 ± 0.63
Insula3.06 ± 0.9
Limbic Lobe3.47 ± 0.7
Mesencephalon3.19 ± 0.66
Myelencephalon3.33 ± 0.6
Occipital Lobe3.32 ± 0.61
Parietal Lobe3.22 ± 0.66
Pontine Tegmentum3.07 ± 0.6
Striatum3.05 ± 0.71
Subthalamus3.25 ± 0.12
Temporal Lobe3.34 ± 0.6
Thalamus3.16 ± 0.58
White Matter3.41 ± 0.79
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
DakCBCerebellum72.95
100
DakCTXCerebral cortex100
90.85
DakHIPHippocampal region91.1
100
DakHPFHippocampal formation100
100
DakHYHypothalamus60.33
47.64
DakLSXLateral septal complex52.44
35.43
DakMBMidbrain64.53
55.46
DakMYMedulla83.34
86.67
DakOLFOlfactory bulb90.28
84.92
DakPPons71.72
69.38
DakPALPallidum64.93
55.15
DakRHPRetrohippocampal region100
100
DaksAMYStriatum-like amygdalar nuclei100
88.46
DakSTRStriatum97.04
70.98
DakSTRdStriatum dorsal region100
76.68
DakSTRvStriatum ventral region86.56
63.05
DakTHThalamus90.53
74.95
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
DHAK_HUMAN_349 24 349 372 SRVAPAEPQEAPDSTAAGGSASKR PRIDE
PAp00004480 31 5 35 KLVNSVAGCADDALAGLVACNPNLQLLQGHR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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