AutismKB 2.0

Annotation Detail for RPAP1


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Basic Information Top
Gene Symbol:RPAP1 ( DKFZp727M111,FLJ12732,KIAA1403,MGC858 )
Gene Full Name: RNA polymerase II associated protein 1
Band: 15q15.1
Quick LinksEntrez ID:26015; OMIM: 611475; Uniprot ID:RPAP1_HUMAN; ENSEMBL ID: ENSG00000103932; HGNC ID: 24567
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst5 / 6231980
fetus33 / 56401258
neonate18 / 31097578
infant1 / 2362042
juvenile5 / 5555689
adult79 / 193912140
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor4 / 34366116
chondrosarcoma6 / 8282372
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor26 / 26384598
glioma8 / 10688374
head and neck tumor6 / 13630244
kidney tumor5 / 6895972
leukemia15 / 95842156
liver tumor3 / 9635931
lung tumor3 / 10312729
lymphoma8 / 71755111
non-neoplasia1 / 9725010
normal180 / 336030753
ovarian tumor3 / 7668239
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS14 / 125680111
prostate cancer1 / 1026809
retinoblastoma4 / 4635686
skin tumor6 / 12494948
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites2 / 4001549
bladder0 / 297570 
blood8 / 12347864
bone3 / 7165541
bone marrow5 / 48801102
brain96 / 110098987
cervix4 / 4817183
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue14 / 21572264
esophagus0 / 202090 
eye7 / 21105433
heart5 / 8962655
intestine9 / 23447238
kidney8 / 21177737
larynx0 / 241450 
liver6 / 20774328
lung7 / 33697420
lymph5 / 44270112
lymph node5 / 9161054
mammary gland3 / 15327119
mouth6 / 6705289
muscle7 / 10771564
nerve1 / 1576863
ovary8 / 10205178
pancreas7 / 21481232
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta19 / 28082567
prostate2 / 18934510
salivary gland0 / 201550 
skin13 / 21057461
spleen1 / 5395218
stomach1 / 9661910
testis36 / 330442108
thymus5 / 8113161
thyroid2 / 4747342
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord18 / 136801315
uterus11 / 23287847
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218441_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.1
Adipocyte7.1
AdrenalCortex6.05
Adrenalgland5
Amygdala6.4
Appendix5.9
AtrioventricularNode4.45
BDCA4+_DentriticCells6.75
Bonemarrow5.85
BronchialEpithelialCells5.95
CD105+_Endothelial6.1
CD14+_Monocytes6.4
CD19+_BCells(neg._sel.)6.45
CD33+_Myeloid7.85
CD34+7.75
CD4+_Tcells8.5
CD56+_NKCells7.25
CD71+_EarlyErythroid5.4
CD8+_Tcells5.9
CardiacMyocytes7.45
Caudatenucleus5.2
Cerebellum4.75
CerebellumPeduncles6.55
CiliaryGanglion4.15
CingulateCortex6.1
Colorectaladenocarcinoma7.5
DorsalRootGanglion4.45
FetalThyroid5.85
Fetalbrain6.05
Fetalliver5.15
Fetallung6.15
GlobusPallidus4.05
Heart7.5
Hypothalamus6.6
Kidney4.7
Leukemia_chronicMyelogenousK-5627.15
Leukemia_promyelocytic-HL-6010.1
Leukemialymphoblastic(MOLT-4)5.3
Liver7.8
Lung6.7
Lymphnode5.2
Lymphoma_burkitts(Daudi)7.85
Lymphoma_burkitts(Raji)8.2
MedullaOblongata5.55
OccipitalLobe5.2
OlfactoryBulb4.75
Ovary3.95
Pancreas4.75
PancreaticIslet6.8
ParietalLobe6.15
Pituitary7
Placenta6.3
Pons5.65
PrefrontalCortex8.25
Prostate7.15
Salivarygland4.7
SkeletalMuscle6.65
Skin4.5
SmoothMuscle6.85
Spinalcord6.4
SubthalamicNucleus5.1
SuperiorCervicalGanglion6.65
TemporalLobe5.3
Testis10.1
TestisGermCell7.2
TestisIntersitial5.15
TestisLeydigCell5.85
TestisSeminiferousTubule6.25
Thalamus5.95
Thymus5.1
Thyroid8.4
Tongue6
Tonsil6.25
Trachea5.05
TrigeminalGanglion5.9
Uterus5
UterusCorpus5.85
WholeBlood6.7
Wholebrain5.2
colon5.8
pineal_day7.36
pineal_night7.28
retina7.3
small_intestine5.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6336_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.99 ± 0.58
Basal Forebrain3.85 ± 0.24
Basal Part of Pons4.01 ± 0.32
Cerebellar Cortex3.84 ± 0.62
Cerebellar Nuclei3.77 ± 0.34
Claustrum4.15 ± 0.46
Epithalamus3.52 ± 0.55
Frontal Lobe3.96 ± 0.45
Globus Pallidus3.65 ± 0.49
Hypothalamus3.55 ± 0.53
Insula3.87 ± 0.47
Limbic Lobe3.96 ± 0.49
Mesencephalon3.77 ± 0.51
Myelencephalon3.92 ± 0.53
Occipital Lobe3.8 ± 0.53
Parietal Lobe3.95 ± 0.43
Pontine Tegmentum3.94 ± 0.49
Striatum3.9 ± 0.43
Subthalamus3.19 ± 0.71
Temporal Lobe3.98 ± 0.45
Thalamus3.94 ± 0.43
White Matter3.81 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rpap1CBCerebellum9.8
9.25
Rpap1CTXCerebral cortex13.85
9.44
Rpap1HIPHippocampal region11.37
10.87
Rpap1HPFHippocampal formation11.17
9.72
Rpap1HYHypothalamus4.81
4.67
Rpap1LSXLateral septal complex4.08
2.62
Rpap1MBMidbrain5.08
4.71
Rpap1MYMedulla7.84
7.66
Rpap1OLFOlfactory bulb13.76
9.79
Rpap1PPons6.53
6.26
Rpap1PALPallidum6.4
5.37
Rpap1RHPRetrohippocampal region10.84
8.06
Rpap1sAMYStriatum-like amygdalar nuclei5.37
3.42
Rpap1STRStriatum4.28
2.92
Rpap1STRdStriatum dorsal region2.31
1.67
Rpap1STRvStriatum ventral region10.49
6.55
Rpap1THThalamus3.62
2.68
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00002983 21 214 234 GLRDQEAEQEAQTIHEENIAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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