AutismKB 2.0

Annotation Detail for LRP10


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Basic Information Top
Gene Symbol:LRP10 ( DKFZp564C1940,LRP9,MGC142274,MGC142276,MGC8675,MST087 )
Gene Full Name: low density lipoprotein receptor-related protein 10
Band: 14q11.2
Quick LinksEntrez ID:26020; OMIM: 609921; Uniprot ID:LRP10_HUMAN; ENSEMBL ID: ENSG00000197324; HGNC ID: 14553
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst4 / 6231964
fetus34 / 56401260
neonate0 / 310970 
infant2 / 2362084
juvenile4 / 5555671
adult305 / 1939121157
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor15 / 94178159
cervical tumor2 / 3436658
chondrosarcoma77 / 82823929
colorectal tumor45 / 114246393
esophageal tumor0 / 172900 
gastrointestinal tumor11 / 11936992
germ cell tumor10 / 26384537
glioma16 / 106883149
head and neck tumor13 / 13630295
kidney tumor18 / 68959261
leukemia18 / 95842187
liver tumor3 / 9635931
lung tumor14 / 103127135
lymphoma11 / 71755153
non-neoplasia11 / 97250113
normal296 / 336030788
ovarian tumor21 / 76682273
pancreatic tumor47 / 104616449
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer6 / 10268058
retinoblastoma2 / 4635643
skin tumor7 / 12494956
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites1 / 4001524
bladder1 / 2975733
blood14 / 123478113
bone17 / 71655237
bone marrow3 / 4880161
brain48 / 110098943
cervix16 / 48171332
connective tissue15 / 149255100
ear1 / 1621261
embryonic tissue17 / 21572278
esophagus0 / 202090 
eye30 / 211054142
heart5 / 8962655
intestine68 / 234472290
kidney31 / 211777146
larynx1 / 2414541
liver4 / 20774319
lung108 / 336974320
lymph1 / 4427022
lymph node12 / 91610130
mammary gland27 / 153271176
mouth1 / 6705214
muscle9 / 10771583
nerve3 / 15768190
ovary23 / 102051225
pancreas60 / 214812279
parathyroid2 / 2053997
pharynx3 / 4132872
pituitary gland1 / 1658560
placenta53 / 280825188
prostate24 / 189345126
salivary gland3 / 20155148
skin26 / 210574123
spleen4 / 5395274
stomach10 / 96619103
testis11 / 33044233
thymus2 / 8113124
thyroid5 / 47473105
tonsil2 / 16999117
trachea1 / 5241319
umbilical cord0 / 136800 
uterus16 / 23287868
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201412_at
Cell line Expression level Expression bar
721_B_lymphoblasts179.8
Adipocyte317.6
AdrenalCortex60.05
Adrenalgland148.9
Amygdala51.65
Appendix90.4
AtrioventricularNode49.4
BDCA4+_DentriticCells351.4
Bonemarrow141
BronchialEpithelialCells369.7
CD105+_Endothelial115.4
CD14+_Monocytes338.5
CD19+_BCells(neg._sel.)355
CD33+_Myeloid386.3
CD34+85.75
CD4+_Tcells195.05
CD56+_NKCells542.9
CD71+_EarlyErythroid377.5
CD8+_Tcells184.9
CardiacMyocytes358.4
Caudatenucleus41.55
Cerebellum19.85
CerebellumPeduncles27.3
CiliaryGanglion54.9
CingulateCortex24.35
Colorectaladenocarcinoma76.05
DorsalRootGanglion54.45
FetalThyroid234.45
Fetalbrain23.45
Fetalliver52.75
Fetallung168.2
GlobusPallidus17.95
Heart297.05
Hypothalamus47.25
Kidney189.85
Leukemia_chronicMyelogenousK-56228.35
Leukemia_promyelocytic-HL-6028.05
Leukemialymphoblastic(MOLT-4)23.75
Liver77.45
Lung861
Lymphnode139.25
Lymphoma_burkitts(Daudi)64.95
Lymphoma_burkitts(Raji)59.7
MedullaOblongata25.4
OccipitalLobe29.3
OlfactoryBulb120.8
Ovary106.25
Pancreas100.45
PancreaticIslet460.3
ParietalLobe25.85
Pituitary55.6
Placenta526.55
Pons28.65
PrefrontalCortex52.2
Prostate571.9
Salivarygland91
SkeletalMuscle29.65
Skin74.15
SmoothMuscle578.7
Spinalcord128.4
SubthalamicNucleus21.8
SuperiorCervicalGanglion41.85
TemporalLobe25.2
Testis50
TestisGermCell57.25
TestisIntersitial30.55
TestisLeydigCell32.6
TestisSeminiferousTubule21.95
Thalamus32.9
Thymus220.7
Thyroid445.75
Tongue116.9
Tonsil180.15
Trachea154.3
TrigeminalGanglion38.45
Uterus224.3
UterusCorpus152.15
WholeBlood1017.5
Wholebrain39.85
colon262.45
pineal_day53.06
pineal_night52.52
retina326.75
small_intestine183.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P926770
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4 ± 0.63
Basal Forebrain3.74 ± 0.42
Basal Part of Pons3.53 ± 0.61
Cerebellar Cortex3.43 ± 0.4
Cerebellar Nuclei4.11 ± 0.44
Claustrum4.24 ± 0.71
Epithalamus3.51 ± 0.51
Frontal Lobe3.74 ± 0.51
Globus Pallidus4.51 ± 0.54
Hypothalamus3.64 ± 0.47
Insula3.49 ± 0.55
Limbic Lobe3.79 ± 0.65
Mesencephalon3.81 ± 0.52
Myelencephalon3.84 ± 0.59
Occipital Lobe3.85 ± 0.61
Parietal Lobe3.79 ± 0.55
Pontine Tegmentum3.74 ± 0.57
Striatum4.16 ± 0.52
Subthalamus3.37 ± 0.78
Temporal Lobe3.63 ± 0.59
Thalamus3.95 ± 0.43
White Matter4.09 ± 0.41
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
LRP10_HUMAN_534 12 534 545 QDMTPGGGPGAR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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