AutismKB 2.0

Annotation Detail for TMEM98


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Basic Information Top
Gene Symbol:TMEM98 ( DKFZp564K1964 )
Gene Full Name: transmembrane protein 98
Band: 17q11.2
Quick LinksEntrez ID:26022; OMIM: NA; Uniprot ID:TMM98_HUMAN; ENSEMBL ID: ENSG00000006042; HGNC ID: 24529
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body12 / 70761169
blastocyst2 / 6231932
fetus24 / 56401242
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult113 / 193912158
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia4 / 9584241
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal180 / 336030753
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS15 / 125680119
prostate cancer4 / 10268038
retinoblastoma2 / 4635643
skin tumor15 / 124949120
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites3 / 4001574
bladder1 / 2975733
blood4 / 12347832
bone3 / 7165541
bone marrow1 / 4880120
brain56 / 110098950
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue20 / 21572292
esophagus0 / 202090 
eye36 / 211054170
heart5 / 8962655
intestine7 / 23447229
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung14 / 33697441
lymph1 / 4427022
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle6 / 10771555
nerve0 / 157680 
ovary5 / 10205148
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland2 / 16585120
placenta32 / 280825113
prostate6 / 18934531
salivary gland0 / 201550 
skin19 / 21057490
spleen0 / 539520 
stomach1 / 9661910
testis3 / 3304429
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P27035
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.86 ± 0.47
Basal Forebrain8.83 ± 0.49
Basal Part of Pons8.12 ± 0.65
Cerebellar Cortex7.98 ± 0.3
Cerebellar Nuclei9.4 ± 0.57
Claustrum7.73 ± 0.53
Epithalamus8.81 ± 0.43
Frontal Lobe8.3 ± 0.77
Globus Pallidus9.97 ± 0.34
Hypothalamus8.42 ± 0.3
Insula7.86 ± 0.34
Limbic Lobe7.79 ± 0.74
Mesencephalon8.46 ± 0.75
Myelencephalon8.44 ± 0.58
Occipital Lobe8.12 ± 0.7
Parietal Lobe8.07 ± 0.71
Pontine Tegmentum8.49 ± 0.61
Striatum9.2 ± 0.59
Subthalamus8.75 ± 0.68
Temporal Lobe8.05 ± 0.55
Thalamus8.76 ± 0.39
White Matter11 ± 0.45
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmem98CBCerebellum54.17
100
Tmem98CTXCerebral cortex100
100
Tmem98HIPHippocampal region94.94
100
Tmem98HPFHippocampal formation100
100
Tmem98HYHypothalamus37.72
38.13
Tmem98LSXLateral septal complex42.5
38.96
Tmem98MBMidbrain61.86
73.89
Tmem98MYMedulla67.13
94.6
Tmem98OLFOlfactory bulb100
100
Tmem98PPons59.79
75.14
Tmem98PALPallidum43.16
51.04
Tmem98RHPRetrohippocampal region100
100
Tmem98sAMYStriatum-like amygdalar nuclei48.59
54.24
Tmem98STRStriatum68.82
69.83
Tmem98STRdStriatum dorsal region81.88
84.14
Tmem98STRvStriatum ventral region46.29
46.06
Tmem98THThalamus57.48
69.65
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018