AutismKB 2.0

Annotation Detail for ACOT11


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Basic Information Top
Gene Symbol:ACOT11 ( BFIT,DKFZp667O1916,KIAA0707,STARD14,THEA,THEM1 )
Gene Full Name: acyl-CoA thioesterase 11
Band: 1p32.3
Quick LinksEntrez ID:26027; OMIM: 606803; Uniprot ID:ACO11_HUMAN; ENSEMBL ID: ENSG00000162390; HGNC ID: 18156
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214763_at
Cell line Expression level Expression bar
721_B_lymphoblasts12.9
Adipocyte11
AdrenalCortex11.75
Adrenalgland10
Amygdala11.7
Appendix11.3
AtrioventricularNode16.45
BDCA4+_DentriticCells11
Bonemarrow10.95
BronchialEpithelialCells14.8
CD105+_Endothelial11.2
CD14+_Monocytes11.85
CD19+_BCells(neg._sel.)11.85
CD33+_Myeloid13.4
CD34+14.5
CD4+_Tcells12.05
CD56+_NKCells12.35
CD71+_EarlyErythroid10.5
CD8+_Tcells9.95
CardiacMyocytes14.25
Caudatenucleus10.95
Cerebellum9.05
CerebellumPeduncles25.15
CiliaryGanglion8.1
CingulateCortex14.4
Colorectaladenocarcinoma13.65
DorsalRootGanglion10.65
FetalThyroid11.3
Fetalbrain11.3
Fetalliver9.6
Fetallung8.6
GlobusPallidus8.25
Heart50.55
Hypothalamus12.1
Kidney40.85
Leukemia_chronicMyelogenousK-56210.15
Leukemia_promyelocytic-HL-6010.1
Leukemialymphoblastic(MOLT-4)10.35
Liver14.7
Lung12
Lymphnode9.55
Lymphoma_burkitts(Daudi)17.1
Lymphoma_burkitts(Raji)15.65
MedullaOblongata10.6
OccipitalLobe16.9
OlfactoryBulb8.65
Ovary7.4
Pancreas12.45
PancreaticIslet12
ParietalLobe14.25
Pituitary15.3
Placenta11.55
Pons11.5
PrefrontalCortex13.9
Prostate13.6
Salivarygland8.95
SkeletalMuscle16.65
Skin8.8
SmoothMuscle12.7
Spinalcord12
SubthalamicNucleus11.15
SuperiorCervicalGanglion19
TemporalLobe15.75
Testis9.65
TestisGermCell9.35
TestisIntersitial10.8
TestisLeydigCell16
TestisSeminiferousTubule9.65
Thalamus15.95
Thymus8.55
Thyroid14.4
Tongue16.25
Tonsil11.3
Trachea9.15
TrigeminalGanglion13.2
Uterus9.2
UterusCorpus14.2
WholeBlood12.45
Wholebrain14.6
colon16
pineal_day15.18
pineal_night14.08
retina15.725
small_intestine15.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1647_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.58 ± 0.95
Basal Forebrain2.19 ± 0.53
Basal Part of Pons1.81 ± 0.29
Cerebellar Cortex2.28 ± 0.73
Cerebellar Nuclei2.38 ± 0.66
Claustrum2.67 ± 0.68
Epithalamus2.36 ± 0.69
Frontal Lobe2.03 ± 0.71
Globus Pallidus2.61 ± 0.72
Hypothalamus2.3 ± 0.92
Insula1.84 ± 0.7
Limbic Lobe2.17 ± 0.79
Mesencephalon2.34 ± 0.76
Myelencephalon2.26 ± 0.8
Occipital Lobe2.32 ± 0.71
Parietal Lobe2.29 ± 0.85
Pontine Tegmentum2.26 ± 0.83
Striatum2.38 ± 0.81
Subthalamus2.15 ± 0.68
Temporal Lobe2.1 ± 0.76
Thalamus2.2 ± 0.66
White Matter2.46 ± 0.85
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Acot11CBCerebellum18.63
24.45
Acot11CTXCerebral cortex8.3
5.93
Acot11HIPHippocampal region4.87
4.23
Acot11HPFHippocampal formation8.89
7.27
Acot11HYHypothalamus0.63
0.47
Acot11LSXLateral septal complex6.84
5.69
Acot11MBMidbrain3.27
3.9
Acot11MYMedulla2.6
2.95
Acot11OLFOlfactory bulb12.45
9.53
Acot11PPons1.44
1.58
Acot11PALPallidum2.18
1.81
Acot11RHPRetrohippocampal region14.45
10.67
Acot11sAMYStriatum-like amygdalar nuclei0.87
0.62
Acot11STRStriatum3.14
2.28
Acot11STRdStriatum dorsal region3.19
2.35
Acot11STRvStriatum ventral region2.79
1.68
Acot11THThalamus3.81
5.58
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000205 20 575 594 ACEQFLLDNRNDLAPSLQTL Peptide Atlas

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018