AutismKB 2.0

Annotation Detail for LRRTM2


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Basic Information Top
Gene Symbol:LRRTM2 ( FLJ76283,FLJ99831 )
Gene Full Name: leucine rich repeat transmembrane neuronal 2
Band: 5q31.2
Quick LinksEntrez ID:26045; OMIM: 610868; Uniprot ID:LRRT2_HUMAN; ENSEMBL ID: ENSG00000146006; HGNC ID: 19409
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12746_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.26 ± 0.45
Basal Forebrain7.55 ± 0.2
Basal Part of Pons7.74 ± 0.35
Cerebellar Cortex7.56 ± 0.27
Cerebellar Nuclei7.44 ± 0.35
Claustrum8.99 ± 0.34
Epithalamus6.92 ± 0.81
Frontal Lobe8.01 ± 0.54
Globus Pallidus7.18 ± 0.63
Hypothalamus7.66 ± 0.47
Insula8.21 ± 0.46
Limbic Lobe8.33 ± 0.45
Mesencephalon7.98 ± 0.44
Myelencephalon7.91 ± 0.54
Occipital Lobe8.12 ± 0.52
Parietal Lobe8.02 ± 0.45
Pontine Tegmentum8.14 ± 0.53
Striatum8.67 ± 0.33
Subthalamus7.27 ± 0.49
Temporal Lobe8.07 ± 0.46
Thalamus8.25 ± 0.56
White Matter7.44 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lrrtm2CBCerebellum1.84
2.28
Lrrtm2CTXCerebral cortex2.2
1.89
Lrrtm2HIPHippocampal region1.78
2.09
Lrrtm2HPFHippocampal formation1.44
1.66
Lrrtm2HYHypothalamus0.75
0.85
Lrrtm2LSXLateral septal complex1.06
0.7
Lrrtm2MBMidbrain1.27
1.48
Lrrtm2MYMedulla1
1.64
Lrrtm2OLFOlfactory bulb1.8
1.54
Lrrtm2PPons1.05
1.36
Lrrtm2PALPallidum0.73
0.69
Lrrtm2RHPRetrohippocampal region1.02
1.2
Lrrtm2sAMYStriatum-like amygdalar nuclei0.27
0.51
Lrrtm2STRStriatum0.75
0.66
Lrrtm2STRdStriatum dorsal region0.49
0.54
Lrrtm2STRvStriatum ventral region1.61
1.03
Lrrtm2THThalamus1.5
1.63
Peptide Top

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018