AutismKB 2.0

Annotation Detail for LTN1


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Basic Information Top
Gene Symbol:LTN1 ( C21orf10,C21orf98,FLJ11053,KIAA0714,RNF160,ZNF294 )
Gene Full Name: listerin E3 ubiquitin protein ligase 1
Band: 21q21.3
Quick LinksEntrez ID:26046; OMIM: 613083; Uniprot ID:LTN1_HUMAN; ENSEMBL ID: ENSG00000198862; HGNC ID: 13082
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst3 / 6231948
fetus7 / 56401212
neonate1 / 3109732
infant0 / 236200 
juvenile2 / 5555635
adult54 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor10 / 26384537
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia4 / 9584241
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal77 / 336030722
ovarian tumor4 / 7668252
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone2 / 7165527
bone marrow6 / 48801122
brain10 / 11009899
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus1 / 2020949
eye2 / 2110549
heart0 / 896260 
intestine6 / 23447225
kidney3 / 21177714
larynx0 / 241450 
liver9 / 20774343
lung3 / 3369748
lymph0 / 442700 
lymph node5 / 9161054
mammary gland5 / 15327132
mouth1 / 6705214
muscle6 / 10771555
nerve1 / 1576863
ovary3 / 10205129
pancreas3 / 21481213
parathyroid2 / 2053997
pharynx6 / 41328145
pituitary gland0 / 165850 
placenta17 / 28082560
prostate1 / 1893455
salivary gland1 / 2015549
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis9 / 33044227
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus3 / 23287812
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215596_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts34.3
Adipocyte10.95
AdrenalCortex13.05
Adrenalgland9.95
Amygdala31.8
Appendix13.25
AtrioventricularNode9.35
BDCA4+_DentriticCells41.7
Bonemarrow11.45
BronchialEpithelialCells16.2
CD105+_Endothelial46.75
CD14+_Monocytes25.65
CD19+_BCells(neg._sel.)40.95
CD33+_Myeloid63.4
CD34+63.75
CD4+_Tcells34.3
CD56+_NKCells68.8
CD71+_EarlyErythroid16.5
CD8+_Tcells53.95
CardiacMyocytes18.8
Caudatenucleus11.05
Cerebellum9.15
CerebellumPeduncles14.05
CiliaryGanglion9.35
CingulateCortex14.25
Colorectaladenocarcinoma18.8
DorsalRootGanglion11.45
FetalThyroid12.1
Fetalbrain15.45
Fetalliver11.4
Fetallung11.45
GlobusPallidus9.35
Heart15.4
Hypothalamus20.8
Kidney9
Leukemia_chronicMyelogenousK-56251.15
Leukemia_promyelocytic-HL-6010.8
Leukemialymphoblastic(MOLT-4)8.25
Liver14.8
Lung9.65
Lymphnode14.6
Lymphoma_burkitts(Daudi)15.85
Lymphoma_burkitts(Raji)18.15
MedullaOblongata10.35
OccipitalLobe12.55
OlfactoryBulb9.05
Ovary8.7
Pancreas9.65
PancreaticIslet12.7
ParietalLobe12.65
Pituitary13.75
Placenta10.35
Pons11.95
PrefrontalCortex29.7
Prostate13.65
Salivarygland10.25
SkeletalMuscle15.45
Skin11.2
SmoothMuscle13.05
Spinalcord15.3
SubthalamicNucleus12.25
SuperiorCervicalGanglion16.45
TemporalLobe10.75
Testis8.75
TestisGermCell15.15
TestisIntersitial9.7
TestisLeydigCell11.7
TestisSeminiferousTubule9.6
Thalamus13.65
Thymus7.35
Thyroid23.5
Tongue12.75
Tonsil11.45
Trachea9.4
TrigeminalGanglion14.15
Uterus18.05
UterusCorpus10.55
WholeBlood15.35
Wholebrain8.7
colon12.65
pineal_day31.16
pineal_night27.98
retina13.425
small_intestine11.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16495_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.7 ± 0.35
Basal Forebrain5.76 ± 0.34
Basal Part of Pons6.08 ± 0.28
Cerebellar Cortex6.05 ± 0.25
Cerebellar Nuclei6.14 ± 0.48
Claustrum5.56 ± 0.59
Epithalamus5.86 ± 0.33
Frontal Lobe5.9 ± 0.38
Globus Pallidus6.03 ± 0.39
Hypothalamus6.05 ± 0.38
Insula5.61 ± 0.34
Limbic Lobe5.67 ± 0.4
Mesencephalon5.83 ± 0.45
Myelencephalon5.83 ± 0.46
Occipital Lobe5.78 ± 0.38
Parietal Lobe5.96 ± 0.44
Pontine Tegmentum5.94 ± 0.31
Striatum5.52 ± 0.36
Subthalamus5.61 ± 0.88
Temporal Lobe5.89 ± 0.33
Thalamus5.94 ± 0.39
White Matter7.33 ± 0.22
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00064036 14 1440 1453 ARPVQIAVYHMLYK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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