AutismKB 2.0

Annotation Detail for SENP6


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SENP6 ( FLJ11355,FLJ11887,KIAA0389,KIAA0797,SSP1,SUSP1 )
Gene Full Name: SUMO1/sentrin specific peptidase 6
Band: 6q14.1
Quick LinksEntrez ID:26054; OMIM: 605003; Uniprot ID:SENP6_HUMAN; ENSEMBL ID: ENSG00000112701; HGNC ID: 20944
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst5 / 6231980
fetus44 / 56401278
neonate3 / 3109796
infant0 / 236200 
juvenile3 / 5555653
adult139 / 193912171
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma4 / 17475228
breast (mammary gland) tumor8 / 9417884
cervical tumor0 / 343660 
chondrosarcoma8 / 8282396
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor14 / 26384553
glioma15 / 106883140
head and neck tumor6 / 13630244
kidney tumor5 / 6895972
leukemia8 / 9584283
liver tumor4 / 9635941
lung tumor0 / 1031270 
lymphoma7 / 7175597
non-neoplasia5 / 9725051
normal233 / 336030769
ovarian tumor3 / 7668239
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor10 / 90257110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites1 / 4001524
bladder3 / 29757100
blood8 / 12347864
bone7 / 7165597
bone marrow5 / 48801102
brain58 / 110098952
cervix0 / 481710 
connective tissue8 / 14925553
ear2 / 16212123
embryonic tissue30 / 215722139
esophagus0 / 202090 
eye14 / 21105466
heart12 / 89626133
intestine14 / 23447259
kidney15 / 21177770
larynx2 / 2414582
liver14 / 20774367
lung27 / 33697480
lymph7 / 44270158
lymph node7 / 9161076
mammary gland13 / 15327184
mouth1 / 6705214
muscle5 / 10771546
nerve1 / 1576863
ovary5 / 10205148
pancreas12 / 21481255
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland4 / 16585241
placenta26 / 28082592
prostate11 / 18934558
salivary gland1 / 2015549
skin12 / 21057456
spleen0 / 539520 
stomach0 / 966190 
testis39 / 330442118
thymus7 / 8113186
thyroid5 / 47473105
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord1 / 1368073
uterus22 / 23287894
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202318_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts132.2
Adipocyte41.3
AdrenalCortex31.85
Adrenalgland13.4
Amygdala59.1
Appendix42.1
AtrioventricularNode29.45
BDCA4+_DentriticCells127.5
Bonemarrow18.6
BronchialEpithelialCells30.4
CD105+_Endothelial43.7
CD14+_Monocytes53.35
CD19+_BCells(neg._sel.)132.3
CD33+_Myeloid60.65
CD34+63.2
CD4+_Tcells127.65
CD56+_NKCells91.5
CD71+_EarlyErythroid37.55
CD8+_Tcells131.1
CardiacMyocytes50.35
Caudatenucleus30.8
Cerebellum17.5
CerebellumPeduncles32.8
CiliaryGanglion25.35
CingulateCortex38.8
Colorectaladenocarcinoma33.2
DorsalRootGanglion31.4
FetalThyroid45.7
Fetalbrain46.95
Fetalliver37.15
Fetallung68.85
GlobusPallidus23.85
Heart35.5
Hypothalamus105.25
Kidney14.8
Leukemia_chronicMyelogenousK-56236.75
Leukemia_promyelocytic-HL-60101.2
Leukemialymphoblastic(MOLT-4)27.7
Liver21.25
Lung16.9
Lymphnode61.55
Lymphoma_burkitts(Daudi)76
Lymphoma_burkitts(Raji)184.15
MedullaOblongata30.8
OccipitalLobe42.55
OlfactoryBulb40.35
Ovary31.75
Pancreas30.1
PancreaticIslet49.9
ParietalLobe38.6
Pituitary77.75
Placenta17.3
Pons18.5
PrefrontalCortex70.15
Prostate27.65
Salivarygland44.85
SkeletalMuscle34.15
Skin25.6
SmoothMuscle71.25
Spinalcord46.25
SubthalamicNucleus39.05
SuperiorCervicalGanglion35.75
TemporalLobe20.65
Testis17.45
TestisGermCell81.75
TestisIntersitial80.6
TestisLeydigCell55.7
TestisSeminiferousTubule45.65
Thalamus41.6
Thymus16.05
Thyroid178.8
Tongue36
Tonsil43.45
Trachea30.1
TrigeminalGanglion27.45
Uterus103.9
UterusCorpus27.75
WholeBlood125.45
Wholebrain25
colon21.95
pineal_day111.4
pineal_night118.88
retina39.675
small_intestine14.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P214156
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.78 ± 0.59
Basal Forebrain4.51 ± 0.63
Basal Part of Pons4.58 ± 0.32
Cerebellar Cortex5.16 ± 0.21
Cerebellar Nuclei4.5 ± 0.45
Claustrum4.83 ± 0.64
Epithalamus4.74 ± 0.63
Frontal Lobe4.67 ± 0.5
Globus Pallidus4.19 ± 0.43
Hypothalamus4.99 ± 0.54
Insula4.74 ± 0.64
Limbic Lobe4.55 ± 0.51
Mesencephalon4.65 ± 0.56
Myelencephalon4.56 ± 0.56
Occipital Lobe4.86 ± 0.4
Parietal Lobe4.71 ± 0.6
Pontine Tegmentum4.84 ± 0.47
Striatum4.22 ± 0.57
Subthalamus4.83 ± 0.26
Temporal Lobe4.59 ± 0.5
Thalamus4.61 ± 0.5
White Matter4.28 ± 0.67
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Senp6CBCerebellum18.71
21.89
Senp6CTXCerebral cortex100
87.93
Senp6HIPHippocampal region73.03
100
Senp6HPFHippocampal formation74.06
96.25
Senp6HYHypothalamus48.66
41.83
Senp6LSXLateral septal complex61.79
49.58
Senp6MBMidbrain25.67
26.35
Senp6MYMedulla11.24
16.48
Senp6OLFOlfactory bulb64.92
62.31
Senp6PPons23.1
29.11
Senp6PALPallidum40.92
37.76
Senp6RHPRetrohippocampal region76.3
68.87
Senp6sAMYStriatum-like amygdalar nuclei66.97
50.65
Senp6STRStriatum45.26
35.32
Senp6STRdStriatum dorsal region39.3
30.32
Senp6STRvStriatum ventral region51.75
40.92
Senp6THThalamus59.35
53.87
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved