AutismKB 2.0

Annotation Detail for RAB11FIP5


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Basic Information Top
Gene Symbol:RAB11FIP5 ( DKFZp434H018,GAF1,KIAA0857,RIP11,pp75 )
Gene Full Name: RAB11 family interacting protein 5 (class I)
Band: 2p13.2
Quick LinksEntrez ID:26056; OMIM: 605536; Uniprot ID:RFIP5_HUMAN; ENSEMBL ID: ENSG00000135631; HGNC ID: 24845
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus9 / 56401215
neonate0 / 310970 
infant4 / 23620169
juvenile0 / 555560 
adult107 / 193912155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor0 / 343660 
chondrosarcoma8 / 8282396
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor16 / 26384560
glioma11 / 106883102
head and neck tumor12 / 13630288
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor8 / 9635983
lung tumor6 / 10312758
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal158 / 336030747
ovarian tumor1 / 7668213
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer9 / 10268087
retinoblastoma4 / 4635686
skin tumor7 / 12494956
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites3 / 4001574
bladder0 / 297570 
blood1 / 1234788
bone8 / 71655111
bone marrow0 / 488010 
brain60 / 110098954
cervix0 / 481710 
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye14 / 21105466
heart2 / 8962622
intestine9 / 23447238
kidney27 / 211777127
larynx1 / 2414541
liver11 / 20774352
lung13 / 33697438
lymph0 / 442700 
lymph node0 / 916100 
mammary gland8 / 15327152
mouth0 / 670520 
muscle5 / 10771546
nerve0 / 157680 
ovary3 / 10205129
pancreas6 / 21481227
parathyroid3 / 20539146
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta17 / 28082560
prostate18 / 18934595
salivary gland11 / 20155545
skin10 / 21057447
spleen9 / 53952166
stomach2 / 9661920
testis37 / 330442111
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus16 / 23287868
vascular4 / 5178077
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210879_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts48.8
Adipocyte60.8
AdrenalCortex54.45
Adrenalgland53
Amygdala74.5
Appendix71.35
AtrioventricularNode45.85
BDCA4+_DentriticCells42.85
Bonemarrow47.75
BronchialEpithelialCells61.1
CD105+_Endothelial47.85
CD14+_Monocytes42.5
CD19+_BCells(neg._sel.)44.8
CD33+_Myeloid51.2
CD34+51.95
CD4+_Tcells42.5
CD56+_NKCells52.35
CD71+_EarlyErythroid43.15
CD8+_Tcells41.15
CardiacMyocytes79.1
Caudatenucleus76.35
Cerebellum86.8
CerebellumPeduncles82.35
CiliaryGanglion49.95
CingulateCortex123.7
Colorectaladenocarcinoma50.55
DorsalRootGanglion110.95
FetalThyroid59.85
Fetalbrain61.75
Fetalliver42.4
Fetallung38.15
GlobusPallidus52.75
Heart117.05
Hypothalamus100
Kidney112.45
Leukemia_chronicMyelogenousK-56245.3
Leukemia_promyelocytic-HL-6035.25
Leukemialymphoblastic(MOLT-4)39.9
Liver53.65
Lung59.45
Lymphnode45
Lymphoma_burkitts(Daudi)65.15
Lymphoma_burkitts(Raji)62.1
MedullaOblongata123.55
OccipitalLobe113.55
OlfactoryBulb38.8
Ovary36.6
Pancreas40.5
PancreaticIslet66.1
ParietalLobe76.75
Pituitary65.3
Placenta234.95
Pons76.85
PrefrontalCortex130.2
Prostate68.8
Salivarygland49
SkeletalMuscle59.25
Skin45.6
SmoothMuscle81.3
Spinalcord70.1
SubthalamicNucleus137.15
SuperiorCervicalGanglion92.65
TemporalLobe134
Testis874.25
TestisGermCell571.55
TestisIntersitial809.2
TestisLeydigCell332.7
TestisSeminiferousTubule369.6
Thalamus175.5
Thymus30.6
Thyroid78.2
Tongue49.45
Tonsil59.85
Trachea61
TrigeminalGanglion99.45
Uterus51
UterusCorpus54.3
WholeBlood51.95
Wholebrain53.25
colon45.7
pineal_day94.52
pineal_night116.2
retina69.125
small_intestine50.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6284_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.73 ± 0.54
Basal Forebrain3.07 ± 0.48
Basal Part of Pons4.12 ± 0.29
Cerebellar Cortex3.58 ± 0.51
Cerebellar Nuclei3.6 ± 0.57
Claustrum3.78 ± 0.65
Epithalamus2.93 ± 0.54
Frontal Lobe3.6 ± 0.59
Globus Pallidus3.86 ± 0.59
Hypothalamus3.36 ± 0.54
Insula3.35 ± 0.54
Limbic Lobe3.73 ± 0.53
Mesencephalon3.59 ± 0.52
Myelencephalon3.53 ± 0.6
Occipital Lobe3.89 ± 0.59
Parietal Lobe3.69 ± 0.6
Pontine Tegmentum3.53 ± 0.61
Striatum3.39 ± 0.73
Subthalamus3.68 ± 0.21
Temporal Lobe3.51 ± 0.57
Thalamus3.7 ± 0.58
White Matter2.42 ± 0.57
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rab11fip5CBCerebellum23.49
35.43
Rab11fip5CTXCerebral cortex23.47
19.6
Rab11fip5HIPHippocampal region19.02
21.14
Rab11fip5HPFHippocampal formation17.27
17.16
Rab11fip5HYHypothalamus3.83
3.1
Rab11fip5LSXLateral septal complex3.89
2.99
Rab11fip5MBMidbrain9.39
9.62
Rab11fip5MYMedulla21.93
27.92
Rab11fip5OLFOlfactory bulb16.02
13.17
Rab11fip5PPons15.68
18.22
Rab11fip5PALPallidum9.13
9.48
Rab11fip5RHPRetrohippocampal region14.59
12.04
Rab11fip5sAMYStriatum-like amygdalar nuclei8.16
6.29
Rab11fip5STRStriatum3.89
3.2
Rab11fip5STRdStriatum dorsal region3.38
2.92
Rab11fip5STRvStriatum ventral region3.15
2.5
Rab11fip5THThalamus24.41
22.23
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp01123758 12 585 596 LKDSAVLDQSAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018