AutismKB 2.0

Annotation Detail for DECR2


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Basic Information Top
Gene Symbol:DECR2 ( PDCR,SDR17C1 )
Gene Full Name: 2,4-dienoyl CoA reductase 2, peroxisomal
Band: 16p13.3
Quick LinksEntrez ID:26063; OMIM: NA; Uniprot ID:DECR2_HUMAN; ENSEMBL ID: ENSG00000103202,ENSG00000242612; HGNC ID: 2754
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus9 / 56401215
neonate1 / 3109732
infant0 / 236200 
juvenile1 / 5555617
adult67 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor6 / 11424652
esophageal tumor2 / 17290115
gastrointestinal tumor19 / 119369159
germ cell tumor0 / 2638450 
glioma6 / 10688356
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia27 / 95842281
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal58 / 336030717
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer4 / 10268038
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood3 / 12347824
bone6 / 7165583
bone marrow23 / 48801471
brain23 / 110098920
cervix2 / 4817141
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus2 / 2020998
eye2 / 2110549
heart0 / 896260 
intestine12 / 23447251
kidney6 / 21177728
larynx0 / 241450 
liver3 / 20774314
lung5 / 33697414
lymph0 / 442700 
lymph node1 / 9161010
mammary gland2 / 15327113
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary1 / 1020519
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate3 / 18934515
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach19 / 96619196
testis6 / 33044218
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus7 / 23287830
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219664_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts41.65
Adipocyte29.5
AdrenalCortex33.7
Adrenalgland24.9
Amygdala37.75
Appendix24.45
AtrioventricularNode21.75
BDCA4+_DentriticCells40.3
Bonemarrow29.85
BronchialEpithelialCells42.45
CD105+_Endothelial127.9
CD14+_Monocytes27.4
CD19+_BCells(neg._sel.)29.85
CD33+_Myeloid31.25
CD34+59.05
CD4+_Tcells34.4
CD56+_NKCells38.25
CD71+_EarlyErythroid149.2
CD8+_Tcells27.05
CardiacMyocytes35.45
Caudatenucleus24.65
Cerebellum24.75
CerebellumPeduncles31.5
CiliaryGanglion19.35
CingulateCortex21.35
Colorectaladenocarcinoma29.4
DorsalRootGanglion21.6
FetalThyroid29.85
Fetalbrain32.1
Fetalliver44.75
Fetallung22.1
GlobusPallidus24.55
Heart50.1
Hypothalamus23.45
Kidney51.75
Leukemia_chronicMyelogenousK-56230
Leukemia_promyelocytic-HL-6036.75
Leukemialymphoblastic(MOLT-4)23.65
Liver288.7
Lung31.95
Lymphnode23.1
Lymphoma_burkitts(Daudi)43.65
Lymphoma_burkitts(Raji)78.65
MedullaOblongata24.6
OccipitalLobe19.15
OlfactoryBulb21.6
Ovary21.25
Pancreas34.4
PancreaticIslet55.85
ParietalLobe29.1
Pituitary38.3
Placenta26.4
Pons22.2
PrefrontalCortex32.5
Prostate52.7
Salivarygland22.4
SkeletalMuscle27.5
Skin25.75
SmoothMuscle32.1
Spinalcord31.65
SubthalamicNucleus19.8
SuperiorCervicalGanglion14.95
TemporalLobe24.95
Testis50.2
TestisGermCell27.8
TestisIntersitial20.4
TestisLeydigCell28
TestisSeminiferousTubule31.2
Thalamus28.4
Thymus25.05
Thyroid40.5
Tongue34.5
Tonsil32.7
Trachea25.35
TrigeminalGanglion27.85
Uterus24.1
UterusCorpus21.65
WholeBlood20.4
Wholebrain23.9
colon29
pineal_day32.7
pineal_night28.82
retina40.5
small_intestine28.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12681_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.71 ± 0.54
Basal Forebrain4.82 ± 0.53
Basal Part of Pons5 ± 0.7
Cerebellar Cortex5.19 ± 0.5
Cerebellar Nuclei4.26 ± 0.51
Claustrum4.28 ± 0.84
Epithalamus5.18 ± 0.7
Frontal Lobe5.01 ± 0.53
Globus Pallidus4.27 ± 0.22
Hypothalamus5.03 ± 0.56
Insula5.21 ± 0.35
Limbic Lobe4.75 ± 0.64
Mesencephalon4.78 ± 0.55
Myelencephalon4.85 ± 0.57
Occipital Lobe4.4 ± 0.57
Parietal Lobe4.77 ± 0.56
Pontine Tegmentum4.69 ± 0.6
Striatum4.44 ± 0.58
Subthalamus4.84 ± 0.21
Temporal Lobe5.13 ± 0.59
Thalamus4.9 ± 0.54
White Matter4.29 ± 0.5
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Decr2CBCerebellum11
11.89
Decr2CTXCerebral cortex22.46
15.94
Decr2HIPHippocampal region16.41
17.05
Decr2HPFHippocampal formation18.1
16.33
Decr2HYHypothalamus3.52
2.64
Decr2LSXLateral septal complex1.84
1.39
Decr2MBMidbrain6.97
6.22
Decr2MYMedulla11.8
12.32
Decr2OLFOlfactory bulb18.11
14.15
Decr2PPons8.87
9
Decr2PALPallidum5.3
4.35
Decr2RHPRetrohippocampal region21.07
15.5
Decr2sAMYStriatum-like amygdalar nuclei6.05
4.14
Decr2STRStriatum3.05
2.12
Decr2STRdStriatum dorsal region2.6
1.83
Decr2STRvStriatum ventral region3.51
2.29
Decr2THThalamus6.21
4.97
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00010362 9 19 27 HLFCPDLLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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