AutismKB 2.0

Annotation Detail for LSM14A


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Basic Information Top
Gene Symbol:LSM14A ( C19orf13,DKFZp434D1335,FAM61A,RAP55,RAP55A )
Gene Full Name: LSM14A, SCD6 homolog A (S. cerevisiae)
Band: 19q13.11
Quick LinksEntrez ID:26065; OMIM: 610677; Uniprot ID:LS14A_HUMAN; ENSEMBL ID: ENSG00000105216; HGNC ID: 24489
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus9 / 56401215
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult35 / 193912118
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor4 / 26384515
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor3 / 6895943
leukemia1 / 9584210
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal56 / 336030716
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites2 / 4001549
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain4 / 11009893
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye1 / 2110544
heart2 / 8962622
intestine4 / 23447217
kidney7 / 21177733
larynx0 / 241450 
liver4 / 20774319
lung3 / 3369748
lymph1 / 4427022
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary1 / 1020519
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate6 / 18934531
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach3 / 9661931
testis4 / 33044212
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus6 / 23287825
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212132_at
Cell line Expression level Expression bar
721_B_lymphoblasts671.6
Adipocyte99.6
AdrenalCortex153.15
Adrenalgland69.3
Amygdala125.55
Appendix72.85
AtrioventricularNode140.7
BDCA4+_DentriticCells498.7
Bonemarrow140.75
BronchialEpithelialCells94
CD105+_Endothelial236.95
CD14+_Monocytes378.1
CD19+_BCells(neg._sel.)555.9
CD33+_Myeloid339.35
CD34+535.6
CD4+_Tcells423.95
CD56+_NKCells727.5
CD71+_EarlyErythroid461.95
CD8+_Tcells555.65
CardiacMyocytes116
Caudatenucleus66.75
Cerebellum47.4
CerebellumPeduncles145.75
CiliaryGanglion131.45
CingulateCortex115.95
Colorectaladenocarcinoma285.55
DorsalRootGanglion106.35
FetalThyroid117.7
Fetalbrain111
Fetalliver109.15
Fetallung149.1
GlobusPallidus108.85
Heart38.25
Hypothalamus147.25
Kidney65.45
Leukemia_chronicMyelogenousK-562204.55
Leukemia_promyelocytic-HL-60339.95
Leukemialymphoblastic(MOLT-4)226.8
Liver80.1
Lung48.45
Lymphnode208.2
Lymphoma_burkitts(Daudi)421.35
Lymphoma_burkitts(Raji)342.4
MedullaOblongata77.9
OccipitalLobe98.45
OlfactoryBulb191.4
Ovary101.5
Pancreas155.8
PancreaticIslet198.75
ParietalLobe117.05
Pituitary162.85
Placenta322.75
Pons56.2
PrefrontalCortex147.95
Prostate203.25
Salivarygland136.9
SkeletalMuscle139.3
Skin117
SmoothMuscle191.85
Spinalcord183.3
SubthalamicNucleus108.95
SuperiorCervicalGanglion70.2
TemporalLobe89
Testis69.15
TestisGermCell247.45
TestisIntersitial158.7
TestisLeydigCell127.45
TestisSeminiferousTubule153.6
Thalamus103.4
Thymus89.7
Thyroid311.1
Tongue135.9
Tonsil341.5
Trachea106.75
TrigeminalGanglion146.55
Uterus180.3
UterusCorpus63.85
WholeBlood438.05
Wholebrain72.35
colon138.1
pineal_day455.74
pineal_night407.14
retina216.275
small_intestine143.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P56069
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.2 ± 0.21
Basal Forebrain8.5 ± 0.13
Basal Part of Pons8.16 ± 0.19
Cerebellar Cortex8.65 ± 0.16
Cerebellar Nuclei8.32 ± 0.15
Claustrum8.18 ± 0.32
Epithalamus8.88 ± 0.34
Frontal Lobe8.33 ± 0.27
Globus Pallidus8.45 ± 0.24
Hypothalamus8.45 ± 0.2
Insula8.35 ± 0.23
Limbic Lobe8.24 ± 0.26
Mesencephalon8.39 ± 0.3
Myelencephalon8.35 ± 0.27
Occipital Lobe8.43 ± 0.24
Parietal Lobe8.33 ± 0.26
Pontine Tegmentum8.42 ± 0.26
Striatum8.39 ± 0.32
Subthalamus8.4 ± 0.15
Temporal Lobe8.32 ± 0.23
Thalamus8.32 ± 0.22
White Matter8.78 ± 0.15
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lsm14aCBCerebellum19.61
20.13
Lsm14aCTXCerebral cortex59.29
44.82
Lsm14aHIPHippocampal region43.32
54.6
Lsm14aHPFHippocampal formation47.55
50.3
Lsm14aHYHypothalamus44.21
37.03
Lsm14aLSXLateral septal complex29.4
23.6
Lsm14aMBMidbrain32.36
29.85
Lsm14aMYMedulla36.71
38.68
Lsm14aOLFOlfactory bulb72.95
61.25
Lsm14aPPons35.54
36.22
Lsm14aPALPallidum41.34
36.79
Lsm14aRHPRetrohippocampal region56.56
44.61
Lsm14asAMYStriatum-like amygdalar nuclei49.23
36.98
Lsm14aSTRStriatum44.81
32.92
Lsm14aSTRdStriatum dorsal region38.99
27.83
Lsm14aSTRvStriatum ventral region73.43
53.24
Lsm14aTHThalamus41.61
35.66
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00064793 13 295 307 DFDFESANAQFNK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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