AutismKB 2.0

Annotation Detail for POLDIP2


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Basic Information Top
Gene Symbol:POLDIP2 ( DKFZp586F1524,PDIP38,POLD4 )
Gene Full Name: polymerase (DNA-directed), delta interacting protein 2
Band: 17q11.2
Quick LinksEntrez ID:26073; OMIM: 611519; Uniprot ID:PDIP2_HUMAN; ENSEMBL ID: ; HGNC ID: 23781
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst4 / 6231964
fetus44 / 56401278
neonate4 / 31097128
infant3 / 23620127
juvenile8 / 55556143
adult221 / 1939121113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor5 / 12794390
bladder carcinoma1 / 1747557
breast (mammary gland) tumor19 / 94178201
cervical tumor8 / 34366232
chondrosarcoma11 / 82823132
colorectal tumor8 / 11424670
esophageal tumor1 / 1729057
gastrointestinal tumor23 / 119369192
germ cell tumor33 / 263845125
glioma24 / 106883224
head and neck tumor20 / 136302146
kidney tumor8 / 68959116
leukemia15 / 95842156
liver tumor12 / 96359124
lung tumor13 / 103127126
lymphoma10 / 71755139
non-neoplasia7 / 9725071
normal286 / 336030785
ovarian tumor22 / 76682286
pancreatic tumor27 / 104616258
primitive neuroectodermal tumor of the CNS22 / 125680175
prostate cancer13 / 102680126
retinoblastoma4 / 4635686
skin tumor20 / 124949160
soft tissue/muscle tissue tumor18 / 125191143
uterine tumor10 / 90257110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland11 / 33197331
ascites12 / 40015299
bladder5 / 29757168
blood15 / 123478121
bone10 / 71655139
bone marrow3 / 4880161
brain110 / 110098999
cervix12 / 48171249
connective tissue6 / 14925540
ear1 / 1621261
embryonic tissue19 / 21572288
esophagus1 / 2020949
eye23 / 211054108
heart7 / 8962678
intestine21 / 23447289
kidney21 / 21177799
larynx7 / 24145289
liver16 / 20774377
lung34 / 336974100
lymph2 / 4427045
lymph node4 / 9161043
mammary gland20 / 153271130
mouth3 / 6705244
muscle15 / 107715139
nerve0 / 157680 
ovary27 / 102051264
pancreas36 / 214812167
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta35 / 280825124
prostate17 / 18934589
salivary gland6 / 20155297
skin36 / 210574170
spleen1 / 5395218
stomach5 / 9661951
testis31 / 33044293
thymus3 / 8113136
thyroid5 / 47473105
tonsil1 / 1699958
trachea2 / 5241338
umbilical cord2 / 13680146
uterus30 / 232878128
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P142442
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.25 ± 0.28
Basal Forebrain9.38 ± 0.12
Basal Part of Pons9.74 ± 0.12
Cerebellar Cortex9.46 ± 0.13
Cerebellar Nuclei9.69 ± 0.22
Claustrum9.13 ± 0.24
Epithalamus9.22 ± 0.15
Frontal Lobe9.58 ± 0.23
Globus Pallidus9.3 ± 0.23
Hypothalamus9.39 ± 0.16
Insula9.56 ± 0.19
Limbic Lobe9.42 ± 0.29
Mesencephalon9.41 ± 0.3
Myelencephalon9.46 ± 0.28
Occipital Lobe9.44 ± 0.23
Parietal Lobe9.56 ± 0.28
Pontine Tegmentum9.45 ± 0.25
Striatum9.32 ± 0.23
Subthalamus9.72 ± 0.09
Temporal Lobe9.5 ± 0.22
Thalamus9.6 ± 0.22
White Matter8.51 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Poldip2CBCerebellum17.58
29.46
Poldip2CTXCerebral cortex49.75
43.84
Poldip2HIPHippocampal region31.77
43.92
Poldip2HPFHippocampal formation35
41.72
Poldip2HYHypothalamus6.53
5.75
Poldip2LSXLateral septal complex9.65
7.43
Poldip2MBMidbrain16.33
17.6
Poldip2MYMedulla17.5
26.5
Poldip2OLFOlfactory bulb25.72
23.74
Poldip2PPons14.2
19.53
Poldip2PALPallidum16.39
17.06
Poldip2RHPRetrohippocampal region40.12
39.2
Poldip2sAMYStriatum-like amygdalar nuclei10.77
8.54
Poldip2STRStriatum10.02
8.59
Poldip2STRdStriatum dorsal region7.69
7.25
Poldip2STRvStriatum ventral region17.56
13.02
Poldip2THThalamus14.05
13.59
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018