AutismKB 2.0

Annotation Detail for GPSM1


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Basic Information Top
Gene Symbol:GPSM1 ( AGS3,DKFZp727I051 )
Gene Full Name: G-protein signaling modulator 1
Band: 9q34.3
Quick LinksEntrez ID:26086; OMIM: 609491; Uniprot ID:GPSM1_HUMAN; ENSEMBL ID: ENSG00000160360; HGNC ID: 17858
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult48 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor10 / 26384537
glioma18 / 106883168
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor7 / 10312767
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal80 / 336030723
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS10 / 12568079
prostate cancer1 / 1026809
retinoblastoma6 / 46356129
skin tumor3 / 12494924
soft tissue/muscle tissue tumor14 / 125191111
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone5 / 7165569
bone marrow0 / 488010 
brain38 / 110098934
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye16 / 21105475
heart1 / 8962611
intestine0 / 2344720 
kidney1 / 2117774
larynx1 / 2414541
liver2 / 2077439
lung15 / 33697444
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth0 / 670520 
muscle6 / 10771555
nerve2 / 15768126
ovary2 / 10205119
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta12 / 28082542
prostate2 / 18934510
salivary gland0 / 201550 
skin5 / 21057423
spleen1 / 5395218
stomach0 / 966190 
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus8 / 23287834
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P340296
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.69 ± 0.93
Basal Forebrain4.2 ± 0.73
Basal Part of Pons3.96 ± 0.58
Cerebellar Cortex4.34 ± 0.48
Cerebellar Nuclei3.97 ± 0.44
Claustrum4.4 ± 0.88
Epithalamus3.71 ± 0.55
Frontal Lobe3.75 ± 0.72
Globus Pallidus4.43 ± 0.42
Hypothalamus3.61 ± 0.44
Insula3.94 ± 0.52
Limbic Lobe3.89 ± 0.7
Mesencephalon4.02 ± 0.71
Myelencephalon3.93 ± 0.71
Occipital Lobe4.03 ± 0.71
Parietal Lobe3.92 ± 0.71
Pontine Tegmentum3.91 ± 0.73
Striatum3.55 ± 0.78
Subthalamus3.53 ± 0.44
Temporal Lobe3.92 ± 0.64
Thalamus3.92 ± 0.68
White Matter4.97 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gpsm1CBCerebellum32.32
36.87
Gpsm1CTXCerebral cortex20.25
13.77
Gpsm1HIPHippocampal region10.07
9.29
Gpsm1HPFHippocampal formation11.07
9.07
Gpsm1HYHypothalamus11.51
8.45
Gpsm1LSXLateral septal complex16.48
11.03
Gpsm1MBMidbrain25.1
20.63
Gpsm1MYMedulla28.37
27.77
Gpsm1OLFOlfactory bulb54.52
69.11
Gpsm1PPons20.66
19.49
Gpsm1PALPallidum9.35
7.54
Gpsm1RHPRetrohippocampal region12.8
8.81
Gpsm1sAMYStriatum-like amygdalar nuclei6.38
4.88
Gpsm1STRStriatum17.69
12.26
Gpsm1STRdStriatum dorsal region16.71
11.7
Gpsm1STRvStriatum ventral region29.54
19.33
Gpsm1THThalamus10.04
7.74
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00039498 15 467 481 APSSDEECFFDLLTK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018