AutismKB 2.0

Annotation Detail for GGA1


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Basic Information Top
Gene Symbol:GGA1 ( - )
Gene Full Name: golgi-associated, gamma adaptin ear containing, ARF binding protein 1
Band: 22q13.1
Quick LinksEntrez ID:26088; OMIM: 606004; Uniprot ID:GGA1_HUMAN; ENSEMBL ID: ENSG00000100083; HGNC ID: 17842
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst12 / 62319192
fetus40 / 56401270
neonate3 / 3109796
infant0 / 236200 
juvenile14 / 55556251
adult133 / 193912168
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor12 / 94178127
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor46 / 119369385
germ cell tumor28 / 263845106
glioma14 / 106883130
head and neck tumor10 / 13630273
kidney tumor7 / 68959101
leukemia11 / 95842114
liver tumor4 / 9635941
lung tumor7 / 10312767
lymphoma21 / 71755292
non-neoplasia7 / 9725071
normal305 / 336030790
ovarian tumor0 / 766820 
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS36 / 125680286
prostate cancer2 / 10268019
retinoblastoma3 / 4635664
skin tumor14 / 124949112
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites43 / 400151074
bladder0 / 297570 
blood11 / 12347889
bone3 / 7165541
bone marrow1 / 4880120
brain115 / 1100989104
cervix3 / 4817162
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue27 / 215722125
esophagus1 / 2020949
eye17 / 21105480
heart3 / 8962633
intestine20 / 23447285
kidney16 / 21177775
larynx1 / 2414541
liver7 / 20774333
lung17 / 33697450
lymph5 / 44270112
lymph node4 / 9161043
mammary gland21 / 153271137
mouth8 / 67052119
muscle3 / 10771527
nerve1 / 1576863
ovary1 / 1020519
pancreas12 / 21481255
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta19 / 28082567
prostate8 / 18934542
salivary gland1 / 2015549
skin16 / 21057475
spleen12 / 53952222
stomach3 / 9661931
testis109 / 330442329
thymus11 / 81131135
thyroid6 / 47473126
tonsil3 / 16999176
trachea1 / 5241319
umbilical cord0 / 136800 
uterus13 / 23287855
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218114_at
Cell line Expression level Expression bar
721_B_lymphoblasts79.75
Adipocyte51.1
AdrenalCortex68.85
Adrenalgland59.2
Amygdala50.9
Appendix52.1
AtrioventricularNode39.75
BDCA4+_DentriticCells59.3
Bonemarrow45.75
BronchialEpithelialCells40.15
CD105+_Endothelial58.15
CD14+_Monocytes56.6
CD19+_BCells(neg._sel.)145.65
CD33+_Myeloid108.45
CD34+66.6
CD4+_Tcells67.95
CD56+_NKCells117.85
CD71+_EarlyErythroid47.5
CD8+_Tcells51.75
CardiacMyocytes62.5
Caudatenucleus45.35
Cerebellum54.2
CerebellumPeduncles112.45
CiliaryGanglion36.3
CingulateCortex52.6
Colorectaladenocarcinoma80.85
DorsalRootGanglion46.5
FetalThyroid52.2
Fetalbrain56.8
Fetalliver40.4
Fetallung47.1
GlobusPallidus36.9
Heart86.95
Hypothalamus57
Kidney41.35
Leukemia_chronicMyelogenousK-56279.05
Leukemia_promyelocytic-HL-6064.4
Leukemialymphoblastic(MOLT-4)53.25
Liver59.8
Lung81.95
Lymphnode55.25
Lymphoma_burkitts(Daudi)94.9
Lymphoma_burkitts(Raji)265.45
MedullaOblongata54.65
OccipitalLobe46.4
OlfactoryBulb49.3
Ovary32.75
Pancreas39.65
PancreaticIslet55.6
ParietalLobe54.3
Pituitary77.15
Placenta58.35
Pons52.95
PrefrontalCortex64.5
Prostate84.6
Salivarygland41.2
SkeletalMuscle59.75
Skin39.3
SmoothMuscle42.35
Spinalcord76.45
SubthalamicNucleus45.7
SuperiorCervicalGanglion58.25
TemporalLobe45.5
Testis1031
TestisGermCell672.2
TestisIntersitial502.7
TestisLeydigCell276.45
TestisSeminiferousTubule456.5
Thalamus60.1
Thymus39
Thyroid179.9
Tongue50.3
Tonsil62.1
Trachea36.65
TrigeminalGanglion58.45
Uterus65.1
UterusCorpus44.25
WholeBlood71.55
Wholebrain44.3
colon32.2
pineal_day70.24
pineal_night63.02
retina65.775
small_intestine26.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1569_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.81 ± 0.88
Basal Forebrain3.82 ± 0.35
Basal Part of Pons3.61 ± 0.66
Cerebellar Cortex4.1 ± 0.3
Cerebellar Nuclei3.7 ± 0.6
Claustrum3.95 ± 0.89
Epithalamus3.27 ± 0.63
Frontal Lobe3.63 ± 0.66
Globus Pallidus3.54 ± 0.75
Hypothalamus3.36 ± 0.41
Insula3.22 ± 0.72
Limbic Lobe3.77 ± 0.59
Mesencephalon3.65 ± 0.55
Myelencephalon3.68 ± 0.61
Occipital Lobe3.8 ± 0.47
Parietal Lobe3.63 ± 0.69
Pontine Tegmentum3.87 ± 0.74
Striatum3.56 ± 0.64
Subthalamus3.42 ± 0.26
Temporal Lobe3.7 ± 0.58
Thalamus3.79 ± 0.6
White Matter4.27 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gga1CBCerebellum100
100
Gga1CTXCerebral cortex100
100
Gga1HIPHippocampal region100
100
Gga1HPFHippocampal formation100
100
Gga1HYHypothalamus100
100
Gga1LSXLateral septal complex100
100
Gga1MBMidbrain100
100
Gga1MYMedulla62.41
100
Gga1OLFOlfactory bulb100
100
Gga1PPons70.97
100
Gga1PALPallidum100
100
Gga1RHPRetrohippocampal region100
100
Gga1sAMYStriatum-like amygdalar nuclei100
100
Gga1STRStriatum100
100
Gga1STRdStriatum dorsal region100
100
Gga1STRvStriatum ventral region100
100
Gga1THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
GGA1_HUMAN_1 13 1 13 MEPAMEPETLEAR PRIDE
PAp00355564 30 266 295 LASDTEDNDEALAEILQANDNLTQVINLYK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018