AutismKB 2.0

Annotation Detail for DCAF4


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Basic Information Top
Gene Symbol:DCAF4 ( DKFZp434K114,MGC20547,MGC46524,WDR21,WDR21A )
Gene Full Name: DDB1 and CUL4 associated factor 4
Band: 14q24.2
Quick LinksEntrez ID:26094; OMIM: NA; Uniprot ID:DCAF4_HUMAN; ENSEMBL ID: ENSG00000119599; HGNC ID: 20229
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus24 / 56401242
neonate3 / 3109796
infant2 / 2362084
juvenile1 / 5555617
adult51 / 193912126
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor3 / 3436687
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor2 / 17290115
gastrointestinal tumor7 / 11936958
germ cell tumor15 / 26384556
glioma6 / 10688356
head and neck tumor3 / 13630222
kidney tumor3 / 6895943
leukemia5 / 9584252
liver tumor4 / 9635941
lung tumor1 / 1031279
lymphoma4 / 7175555
non-neoplasia3 / 9725030
normal111 / 336030733
ovarian tumor6 / 7668278
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor7 / 12494956
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood7 / 12347856
bone0 / 716550 
bone marrow1 / 4880120
brain55 / 110098949
cervix3 / 4817162
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus2 / 2020998
eye4 / 21105418
heart2 / 8962622
intestine5 / 23447221
kidney10 / 21177747
larynx0 / 241450 
liver5 / 20774324
lung5 / 33697414
lymph0 / 442700 
lymph node3 / 9161032
mammary gland5 / 15327132
mouth2 / 6705229
muscle3 / 10771527
nerve0 / 157680 
ovary6 / 10205158
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate3 / 18934515
salivary gland0 / 201550 
skin11 / 21057452
spleen2 / 5395237
stomach4 / 9661941
testis10 / 33044230
thymus1 / 8113112
thyroid2 / 4747342
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus11 / 23287847
vascular3 / 5178057
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P241318
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.87 ± 0.52
Basal Forebrain6.06 ± 0.35
Basal Part of Pons6.56 ± 0.36
Cerebellar Cortex5.93 ± 0.23
Cerebellar Nuclei6.29 ± 0.5
Claustrum6.21 ± 0.52
Epithalamus5.95 ± 0.21
Frontal Lobe6.43 ± 0.4
Globus Pallidus5.71 ± 0.57
Hypothalamus7.26 ± 0.76
Insula6.66 ± 0.37
Limbic Lobe6.23 ± 0.55
Mesencephalon6.13 ± 0.47
Myelencephalon6.18 ± 0.6
Occipital Lobe5.7 ± 0.68
Parietal Lobe6.25 ± 0.53
Pontine Tegmentum6.31 ± 0.6
Striatum5.67 ± 0.69
Subthalamus6.73 ± 0.29
Temporal Lobe6.53 ± 0.45
Thalamus5.99 ± 0.43
White Matter5.83 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Wdr21CBCerebellum12.57
9.59
Wdr21CTXCerebral cortex10.14
5.67
Wdr21HIPHippocampal region12.9
6.59
Wdr21HPFHippocampal formation13.85
8.09
Wdr21HYHypothalamus4.25
2.21
Wdr21LSXLateral septal complex3.92
1.94
Wdr21MBMidbrain2.42
1.74
Wdr21MYMedulla10.8
8.4
Wdr21OLFOlfactory bulb11.54
5.93
Wdr21PPons5.23
3.38
Wdr21PALPallidum4.18
2.68
Wdr21RHPRetrohippocampal region15.95
10.28
Wdr21sAMYStriatum-like amygdalar nuclei6.39
3.39
Wdr21STRStriatum6.17
3.02
Wdr21STRdStriatum dorsal region6.3
3.16
Wdr21STRvStriatum ventral region6.94
2.92
Wdr21THThalamus2.97
1.58
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018