AutismKB 2.0

Annotation Detail for LRIT1


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Basic Information Top
Gene Symbol:LRIT1 ( DKFZp434K091,FIGLER9,LRRC21,PAL )
Gene Full Name: leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
Band: 10q23.1
Quick LinksEntrez ID:26103; OMIM: NA; Uniprot ID:LRIT1_HUMAN; ENSEMBL ID: ENSG00000148602; HGNC ID: 23404
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult3 / 19391211
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal4 / 33603071
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211353_at
Cell line Expression level Expression bar
721_B_lymphoblasts5
Adipocyte4.05
AdrenalCortex4.3
Adrenalgland3.4
Amygdala4.2
Appendix4.8
AtrioventricularNode3.1
BDCA4+_DentriticCells4.4
Bonemarrow4
BronchialEpithelialCells3.95
CD105+_Endothelial4.05
CD14+_Monocytes4.3
CD19+_BCells(neg._sel.)4.35
CD33+_Myeloid5.15
CD34+5.1
CD4+_Tcells4.35
CD56+_NKCells4.8
CD71+_EarlyErythroid3.8
CD8+_Tcells3.85
CardiacMyocytes5.25
Caudatenucleus3.6
Cerebellum3.3
CerebellumPeduncles4.55
CiliaryGanglion2.9
CingulateCortex4.1
Colorectaladenocarcinoma4.05
DorsalRootGanglion3.1
FetalThyroid3.9
Fetalbrain3.95
Fetalliver3.5
Fetallung3.3
GlobusPallidus2.95
Heart5.3
Hypothalamus4.4
Kidney3.3
Leukemia_chronicMyelogenousK-5623.65
Leukemia_promyelocytic-HL-603.55
Leukemialymphoblastic(MOLT-4)3.2
Liver5.4
Lung4.45
Lymphnode3.45
Lymphoma_burkitts(Daudi)5.15
Lymphoma_burkitts(Raji)5.7
MedullaOblongata3.65
OccipitalLobe3.6
OlfactoryBulb3.2
Ovary2.65
Pancreas3.2
PancreaticIslet4.3
ParietalLobe4.25
Pituitary4.7
Placenta4.15
Pons3.8
PrefrontalCortex5
Prostate4.7
Salivarygland3.2
SkeletalMuscle4.8
Skin3.1
SmoothMuscle4.55
Spinalcord4.3
SubthalamicNucleus3.7
SuperiorCervicalGanglion4.7
TemporalLobe3.7
Testis3.65
TestisGermCell3.4
TestisIntersitial3.4
TestisLeydigCell4.05
TestisSeminiferousTubule3.45
Thalamus4.1
Thymus3.15
Thyroid5
Tongue4
Tonsil3.9
Trachea3.4
TrigeminalGanglion4.05
Uterus3.25
UterusCorpus3.65
WholeBlood4.4
Wholebrain3.4
colon4.05
pineal_day5.22
pineal_night6.2
retina4.825
small_intestine3.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6297_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.31 ± 0.85
Basal Forebrain1.71 ± 0.54
Basal Part of Pons1.5 ± 0.74
Cerebellar Cortex1.69 ± 0.78
Cerebellar Nuclei2.21 ± 0.73
Claustrum2.52 ± 1.06
Epithalamus1.24 ± 0.75
Frontal Lobe1.87 ± 0.81
Globus Pallidus2.57 ± 0.56
Hypothalamus1.8 ± 0.47
Insula1.87 ± 0.96
Limbic Lobe1.9 ± 0.76
Mesencephalon2.01 ± 0.81
Myelencephalon1.94 ± 0.76
Occipital Lobe1.82 ± 0.75
Parietal Lobe1.89 ± 0.88
Pontine Tegmentum1.88 ± 0.72
Striatum2.05 ± 0.85
Subthalamus1.66 ± 0.79
Temporal Lobe1.82 ± 0.82
Thalamus1.95 ± 0.73
White Matter2.07 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lrrc21CBCerebellum0.15
0.38
Lrrc21CTXCerebral cortex0.38
0.68
Lrrc21HIPHippocampal region0.15
0.21
Lrrc21HPFHippocampal formation0.16
0.17
Lrrc21HYHypothalamus0.02
0.06
Lrrc21LSXLateral septal complex0.04
0
Lrrc21MBMidbrain0.13
0.27
Lrrc21MYMedulla0.06
0.16
Lrrc21OLFOlfactory bulb0.47
2.09
Lrrc21PPons0.11
0.29
Lrrc21PALPallidum0.01
0
Lrrc21RHPRetrohippocampal region0.08
0.06
Lrrc21sAMYStriatum-like amygdalar nuclei0.14
0.27
Lrrc21STRStriatum0.04
0.07
Lrrc21STRdStriatum dorsal region0.03
0.04
Lrrc21STRvStriatum ventral region0.03
0.06
Lrrc21THThalamus0.12
0.1
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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