AutismKB 2.0

Annotation Detail for PYGO1


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Basic Information Top
Gene Symbol:PYGO1 ( DKFZp547G0910 )
Gene Full Name: pygopus homolog 1 (Drosophila)
Band: 15q21.3
Quick LinksEntrez ID:26108; OMIM: 606902; Uniprot ID:PYGO1_HUMAN; ENSEMBL ID: ENSG00000171016; HGNC ID: 30256
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult3 / 19391211
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal6 / 33603071
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain3 / 11009892
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215517_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.6
Adipocyte4.45
AdrenalCortex5.2
Adrenalgland3.95
Amygdala4.7
Appendix5.15
AtrioventricularNode3.8
BDCA4+_DentriticCells4.95
Bonemarrow4.65
BronchialEpithelialCells4.45
CD105+_Endothelial4.6
CD14+_Monocytes4.85
CD19+_BCells(neg._sel.)4.8
CD33+_Myeloid5.75
CD34+5.65
CD4+_Tcells4.85
CD56+_NKCells5.4
CD71+_EarlyErythroid4.25
CD8+_Tcells4.3
CardiacMyocytes6.1
Caudatenucleus4.1
Cerebellum3.65
CerebellumPeduncles5.3
CiliaryGanglion3.45
CingulateCortex4.75
Colorectaladenocarcinoma4.55
DorsalRootGanglion3.65
FetalThyroid4.45
Fetalbrain4.5
Fetalliver3.95
Fetallung3.65
GlobusPallidus3.6
Heart6.2
Hypothalamus4.9
Kidney3.85
Leukemia_chronicMyelogenousK-5624.1
Leukemia_promyelocytic-HL-604.05
Leukemialymphoblastic(MOLT-4)3.6
Liver6.1
Lung4.95
Lymphnode3.9
Lymphoma_burkitts(Daudi)5.95
Lymphoma_burkitts(Raji)6.55
MedullaOblongata4.1
OccipitalLobe4.05
OlfactoryBulb3.6
Ovary3.25
Pancreas3.8
PancreaticIslet4.85
ParietalLobe4.95
Pituitary5.3
Placenta4.65
Pons4.4
PrefrontalCortex5.6
Prostate5.25
Salivarygland3.75
SkeletalMuscle7.15
Skin3.85
SmoothMuscle5.1
Spinalcord4.85
SubthalamicNucleus4.25
SuperiorCervicalGanglion5.45
TemporalLobe4.25
Testis3.9
TestisGermCell3.7
TestisIntersitial3.95
TestisLeydigCell4.55
TestisSeminiferousTubule3.9
Thalamus4.65
Thymus3.55
Thyroid5.6
Tongue5.15
Tonsil4.45
Trachea3.8
TrigeminalGanglion5.25
Uterus3.65
UterusCorpus4.2
WholeBlood4.95
Wholebrain3.8
colon4.55
pineal_day5.66
pineal_night5.56
retina5.5
small_intestine4.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6062_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.46 ± 0.61
Basal Forebrain5.49 ± 0.13
Basal Part of Pons4.85 ± 0.42
Cerebellar Cortex5.63 ± 0.31
Cerebellar Nuclei4.96 ± 0.44
Claustrum5.16 ± 0.47
Epithalamus5.32 ± 0.24
Frontal Lobe5.01 ± 0.51
Globus Pallidus5.68 ± 0.57
Hypothalamus5.41 ± 0.38
Insula5.05 ± 0.48
Limbic Lobe5.2 ± 0.47
Mesencephalon5.37 ± 0.49
Myelencephalon5.18 ± 0.55
Occipital Lobe5.22 ± 0.57
Parietal Lobe5.09 ± 0.55
Pontine Tegmentum5.25 ± 0.46
Striatum5.47 ± 0.62
Subthalamus5.03 ± 0.28
Temporal Lobe5.03 ± 0.49
Thalamus5.09 ± 0.53
White Matter5.1 ± 0.43
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pygo1CBCerebellum49.18
69.74
Pygo1LSXLateral septal complex17.52
12.66
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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