AutismKB 2.0

Annotation Detail for TANC2


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Basic Information Top
Gene Symbol:TANC2 ( DKFZp564D166,FLJ10215,FLJ11824,KIAA1148,KIAA1636,ROLSA,rols )
Gene Full Name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
Band: 17q23.2-q23.3
Quick LinksEntrez ID:26115; OMIM: NA; Uniprot ID:TANC2_HUMAN; ENSEMBL ID: ENSG00000170921; HGNC ID: 30212
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus66 / 564012117
neonate1 / 3109732
infant0 / 236200 
juvenile3 / 5555653
adult79 / 193912140
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma6 / 10688356
head and neck tumor9 / 13630266
kidney tumor5 / 6895972
leukemia1 / 9584210
liver tumor3 / 9635931
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal184 / 336030754
ovarian tumor6 / 7668278
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone5 / 7165569
bone marrow1 / 4880120
brain100 / 110098990
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye8 / 21105437
heart4 / 8962644
intestine3 / 23447212
kidney8 / 21177737
larynx6 / 24145248
liver5 / 20774324
lung14 / 33697441
lymph0 / 442700 
lymph node0 / 916100 
mammary gland7 / 15327145
mouth2 / 6705229
muscle2 / 10771518
nerve3 / 15768190
ovary7 / 10205168
pancreas1 / 2148124
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland2 / 16585120
placenta9 / 28082532
prostate3 / 18934515
salivary gland0 / 201550 
skin4 / 21057418
spleen1 / 5395218
stomach0 / 966190 
testis20 / 33044260
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus11 / 23287847
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208425_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.65
Adipocyte5.7
AdrenalCortex6.4
Adrenalgland5.15
Amygdala6.3
Appendix10
AtrioventricularNode5.2
BDCA4+_DentriticCells6.15
Bonemarrow6.05
BronchialEpithelialCells5.85
CD105+_Endothelial5.9
CD14+_Monocytes6.2
CD19+_BCells(neg._sel.)6.15
CD33+_Myeloid7.2
CD34+7.45
CD4+_Tcells6.1
CD56+_NKCells6.75
CD71+_EarlyErythroid5.5
CD8+_Tcells5.65
CardiacMyocytes8.85
Caudatenucleus5.3
Cerebellum4.8
CerebellumPeduncles6.95
CiliaryGanglion4.6
CingulateCortex6.1
Colorectaladenocarcinoma5.85
DorsalRootGanglion4.65
FetalThyroid5.75
Fetalbrain5.7
Fetalliver5.1
Fetallung4.55
GlobusPallidus4.45
Heart8.55
Hypothalamus6.35
Kidney5
Leukemia_chronicMyelogenousK-5625.3
Leukemia_promyelocytic-HL-605.2
Leukemialymphoblastic(MOLT-4)4.65
Liver9.2
Lung6.45
Lymphnode4.85
Lymphoma_burkitts(Daudi)7.7
Lymphoma_burkitts(Raji)8.6
MedullaOblongata6.4
OccipitalLobe5.25
OlfactoryBulb4.65
Ovary3.95
Pancreas4.7
PancreaticIslet6.35
ParietalLobe6.35
Pituitary6.85
Placenta6.1
Pons5.55
PrefrontalCortex7.3
Prostate6.85
Salivarygland4.8
SkeletalMuscle7.75
Skin4.45
SmoothMuscle6.75
Spinalcord6.3
SubthalamicNucleus5.3
SuperiorCervicalGanglion17.4
TemporalLobe5.5
Testis5.1
TestisGermCell4.9
TestisIntersitial5.05
TestisLeydigCell6.05
TestisSeminiferousTubule5.05
Thalamus6
Thymus4.6
Thyroid7.25
Tongue5.9
Tonsil5.75
Trachea4.95
TrigeminalGanglion6.05
Uterus4.8
UterusCorpus5.4
WholeBlood6.55
Wholebrain5.15
colon5.95
pineal_day7.28
pineal_night7.06
retina7.1
small_intestine5.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P218346
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.77 ± 0.65
Basal Forebrain7.96 ± 0.27
Basal Part of Pons8.27 ± 0.29
Cerebellar Cortex7.52 ± 0.27
Cerebellar Nuclei7.78 ± 0.4
Claustrum8.3 ± 0.3
Epithalamus7.61 ± 0.43
Frontal Lobe7.98 ± 0.39
Globus Pallidus7.31 ± 0.76
Hypothalamus7.78 ± 0.53
Insula8.11 ± 0.37
Limbic Lobe8.17 ± 0.36
Mesencephalon7.82 ± 0.4
Myelencephalon7.96 ± 0.4
Occipital Lobe8.33 ± 0.4
Parietal Lobe8.05 ± 0.41
Pontine Tegmentum7.96 ± 0.41
Striatum8.46 ± 0.29
Subthalamus7.04 ± 0.53
Temporal Lobe8.09 ± 0.38
Thalamus8.01 ± 0.27
White Matter7.74 ± 0.77
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tanc2CBCerebellum0.65
1.45
Tanc2CTXCerebral cortex0.7
0.86
Tanc2HIPHippocampal region0.87
0.81
Tanc2HPFHippocampal formation0.64
0.54
Tanc2HYHypothalamus0.02
0.02
Tanc2LSXLateral septal complex0
0
Tanc2MBMidbrain0.12
0.14
Tanc2MYMedulla0.38
0.55
Tanc2OLFOlfactory bulb0.86
0.66
Tanc2PPons0.14
0.27
Tanc2PALPallidum0.04
0.04
Tanc2RHPRetrohippocampal region0.24
0.15
Tanc2sAMYStriatum-like amygdalar nuclei0.12
0.06
Tanc2STRStriatum0.06
0.04
Tanc2STRdStriatum dorsal region0.08
0.05
Tanc2STRvStriatum ventral region0.03
0.01
Tanc2THThalamus0.11
0.19
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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