AutismKB 2.0

Annotation Detail for SERBP1


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Basic Information Top
Gene Symbol:SERBP1 ( CHD3IP,DKFZp564M2423,FLJ90489,HABP4L,PAI-RBP1,PAIRBP1 )
Gene Full Name: SERPINE1 mRNA binding protein 1
Band: 1p31.3
Quick LinksEntrez ID:26135; OMIM: 607378; Uniprot ID:PAIRB_HUMAN; ENSEMBL ID: ENSG00000142864; HGNC ID: 17860
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus16 / 56401228
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult38 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma1 / 1068839
head and neck tumor5 / 13630236
kidney tumor4 / 6895958
leukemia0 / 958420 
liver tumor6 / 9635962
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal42 / 336030712
ovarian tumor3 / 7668239
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone2 / 7165527
bone marrow0 / 488010 
brain10 / 11009899
cervix1 / 4817120
connective tissue1 / 1492556
ear3 / 16212185
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye1 / 2110544
heart2 / 8962622
intestine2 / 2344728
kidney11 / 21177751
larynx0 / 241450 
liver6 / 20774328
lung5 / 33697414
lymph0 / 442700 
lymph node1 / 9161010
mammary gland3 / 15327119
mouth4 / 6705259
muscle4 / 10771537
nerve0 / 157680 
ovary3 / 10205129
pancreas4 / 21481218
parathyroid3 / 20539146
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta5 / 28082517
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach1 / 9661910
testis7 / 33044221
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209669_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts1043.65
Adipocyte185.1
AdrenalCortex46
Adrenalgland31.5
Amygdala68.1
Appendix27.65
AtrioventricularNode25.9
BDCA4+_DentriticCells568.2
Bonemarrow40.3
BronchialEpithelialCells338.8
CD105+_Endothelial915.5
CD14+_Monocytes221.05
CD19+_BCells(neg._sel.)472.15
CD33+_Myeloid401.1
CD34+917.65
CD4+_Tcells275
CD56+_NKCells674.6
CD71+_EarlyErythroid417.85
CD8+_Tcells253.4
CardiacMyocytes181.9
Caudatenucleus17.3
Cerebellum9.3
CerebellumPeduncles57.85
CiliaryGanglion33.15
CingulateCortex50.7
Colorectaladenocarcinoma193.85
DorsalRootGanglion21.25
FetalThyroid137.4
Fetalbrain71.95
Fetalliver78.25
Fetallung87.25
GlobusPallidus9.9
Heart17.2
Hypothalamus59.7
Kidney20.8
Leukemia_chronicMyelogenousK-562227.2
Leukemia_promyelocytic-HL-60278.7
Leukemialymphoblastic(MOLT-4)132.1
Liver68.85
Lung150.35
Lymphnode58.65
Lymphoma_burkitts(Daudi)348.65
Lymphoma_burkitts(Raji)708.9
MedullaOblongata25.5
OccipitalLobe31.5
OlfactoryBulb102.55
Ovary28.95
Pancreas126.05
PancreaticIslet99.85
ParietalLobe29.05
Pituitary47.65
Placenta65.2
Pons19.25
PrefrontalCortex44.9
Prostate423.95
Salivarygland41.35
SkeletalMuscle75.2
Skin40.75
SmoothMuscle184.3
Spinalcord26.55
SubthalamicNucleus38.5
SuperiorCervicalGanglion9.8
TemporalLobe16.1
Testis61.55
TestisGermCell141.4
TestisIntersitial141.8
TestisLeydigCell92.6
TestisSeminiferousTubule63.7
Thalamus19.5
Thymus127.25
Thyroid285.55
Tongue128.15
Tonsil142.5
Trachea47.9
TrigeminalGanglion9.9
Uterus168.15
UterusCorpus16.35
WholeBlood100.2
Wholebrain43.65
colon292.2
pineal_day117.08
pineal_night114.16
retina53.825
small_intestine235.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P337422
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.86 ± 0.41
Basal Forebrain6.22 ± 0.22
Basal Part of Pons5.47 ± 0.37
Cerebellar Cortex6.3 ± 0.19
Cerebellar Nuclei5.66 ± 0.27
Claustrum6.02 ± 0.67
Epithalamus6.3 ± 0.2
Frontal Lobe5.84 ± 0.37
Globus Pallidus5.79 ± 0.43
Hypothalamus6.01 ± 0.31
Insula6.03 ± 0.33
Limbic Lobe5.83 ± 0.34
Mesencephalon5.89 ± 0.43
Myelencephalon5.95 ± 0.42
Occipital Lobe6.07 ± 0.36
Parietal Lobe5.92 ± 0.34
Pontine Tegmentum5.97 ± 0.44
Striatum5.97 ± 0.4
Subthalamus5.88 ± 0.67
Temporal Lobe5.94 ± 0.36
Thalamus5.98 ± 0.37
White Matter5.65 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Serbp1CBCerebellum100
100
Serbp1CTXCerebral cortex100
100
Serbp1HIPHippocampal region100
100
Serbp1HPFHippocampal formation100
100
Serbp1HYHypothalamus100
100
Serbp1LSXLateral septal complex100
100
Serbp1MBMidbrain100
100
Serbp1MYMedulla80.77
100
Serbp1OLFOlfactory bulb100
100
Serbp1PPons97.29
100
Serbp1PALPallidum100
100
Serbp1RHPRetrohippocampal region100
100
Serbp1sAMYStriatum-like amygdalar nuclei100
100
Serbp1STRStriatum100
100
Serbp1STRdStriatum dorsal region100
100
Serbp1STRvStriatum ventral region100
100
Serbp1THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAIRB_HUMAN_2 15 2 16 PGHLQEGFGCVVTNR PRIDE
PAIRB_HUMAN_327 18 327 344 SKSEEAHAEDSVMDHHFR PRIDE
PAIRB_HUMAN_328 18 328 345 SKSEEAHAEDSVMDHHFR PRIDE
PAIRB_HUMAN_330 16 330 345 SEEAHAEDSVMDHHFR PRIDE
PAIRB_HUMAN_389 20 389 408 DKSSASAPDVDDPEAFPALA PRIDE
PAp00001575 30 229 258 DELTDLDQSNVTEETPEGEEHHPVADTENK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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