AutismKB 2.0

Annotation Detail for NOC2L


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Basic Information Top
Gene Symbol:NOC2L ( DKFZp564C186,FLJ35172,NET15,NET7,NIR )
Gene Full Name: nucleolar complex associated 2 homolog (S. cerevisiae)
Band: 1p36.33
Quick LinksEntrez ID:26155; OMIM: 610770; Uniprot ID:NOC2L_HUMAN; ENSEMBL ID: ENSG00000188976; HGNC ID: 24517
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body11 / 70761155
blastocyst15 / 62319240
fetus48 / 56401285
neonate2 / 3109764
infant1 / 2362042
juvenile8 / 55556143
adult211 / 1939121108
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor27 / 94178286
cervical tumor12 / 34366349
chondrosarcoma8 / 8282396
colorectal tumor26 / 114246227
esophageal tumor1 / 1729057
gastrointestinal tumor29 / 119369242
germ cell tumor44 / 263845166
glioma8 / 10688374
head and neck tumor28 / 136302205
kidney tumor11 / 68959159
leukemia10 / 95842104
liver tumor4 / 9635941
lung tumor23 / 103127223
lymphoma14 / 71755195
non-neoplasia1 / 9725010
normal215 / 336030763
ovarian tumor10 / 76682130
pancreatic tumor17 / 104616162
primitive neuroectodermal tumor of the CNS30 / 125680238
prostate cancer13 / 102680126
retinoblastoma13 / 46356280
skin tumor50 / 124949400
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor10 / 90257110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites17 / 40015424
bladder2 / 2975767
blood6 / 12347848
bone10 / 71655139
bone marrow8 / 48801163
brain94 / 110098985
cervix14 / 48171290
connective tissue2 / 14925513
ear1 / 1621261
embryonic tissue30 / 215722139
esophagus1 / 2020949
eye18 / 21105485
heart3 / 8962633
intestine43 / 234472183
kidney24 / 211777113
larynx13 / 24145538
liver21 / 207743101
lung35 / 336974103
lymph11 / 44270248
lymph node3 / 9161032
mammary gland33 / 153271215
mouth10 / 67052149
muscle7 / 10771564
nerve1 / 1576863
ovary17 / 102051166
pancreas19 / 21481288
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta21 / 28082574
prostate19 / 189345100
salivary gland5 / 20155248
skin55 / 210574261
spleen4 / 5395274
stomach9 / 9661993
testis24 / 33044272
thymus7 / 8113186
thyroid6 / 47473126
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus20 / 23287885
vascular7 / 51780135
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202115_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts330.3
Adipocyte35
AdrenalCortex37.85
Adrenalgland30.1
Amygdala39.35
Appendix32.95
AtrioventricularNode22.9
BDCA4+_DentriticCells111.3
Bonemarrow26.95
BronchialEpithelialCells100.85
CD105+_Endothelial81.9
CD14+_Monocytes48.5
CD19+_BCells(neg._sel.)41.05
CD33+_Myeloid56.05
CD34+70.8
CD4+_Tcells42.5
CD56+_NKCells101.05
CD71+_EarlyErythroid35
CD8+_Tcells52.95
CardiacMyocytes64.45
Caudatenucleus34
Cerebellum32.85
CerebellumPeduncles42.65
CiliaryGanglion22.95
CingulateCortex38.65
Colorectaladenocarcinoma85.2
DorsalRootGanglion26.95
FetalThyroid52.25
Fetalbrain37.05
Fetalliver32.15
Fetallung32.1
GlobusPallidus25.35
Heart56.2
Hypothalamus40.05
Kidney29.95
Leukemia_chronicMyelogenousK-56284.35
Leukemia_promyelocytic-HL-60113.25
Leukemialymphoblastic(MOLT-4)30.35
Liver67.4
Lung41
Lymphnode30
Lymphoma_burkitts(Daudi)57.35
Lymphoma_burkitts(Raji)271.05
MedullaOblongata29.8
OccipitalLobe32.05
OlfactoryBulb29.8
Ovary24.75
Pancreas27.8
PancreaticIslet54.65
ParietalLobe39.75
Pituitary47.55
Placenta38.85
Pons36.25
PrefrontalCortex48.55
Prostate43.4
Salivarygland26.05
SkeletalMuscle45.6
Skin21.95
SmoothMuscle50.8
Spinalcord40.65
SubthalamicNucleus34
SuperiorCervicalGanglion21.3
TemporalLobe34.4
Testis41.15
TestisGermCell39.25
TestisIntersitial37.85
TestisLeydigCell37.3
TestisSeminiferousTubule50.1
Thalamus44.25
Thymus30.55
Thyroid49.3
Tongue33.95
Tonsil32.35
Trachea29.9
TrigeminalGanglion28.75
Uterus30.25
UterusCorpus29.5
WholeBlood17.4
Wholebrain29.55
colon38.25
pineal_day54.5
pineal_night61.52
retina43.475
small_intestine36.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P336015
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.23 ± 0.55
Basal Forebrain4.3 ± 0.33
Basal Part of Pons4.8 ± 0.29
Cerebellar Cortex4.44 ± 0.55
Cerebellar Nuclei4.1 ± 0.47
Claustrum4.4 ± 0.62
Epithalamus4.08 ± 0.59
Frontal Lobe4.34 ± 0.47
Globus Pallidus3.79 ± 0.45
Hypothalamus4 ± 0.59
Insula4.26 ± 0.51
Limbic Lobe4.57 ± 0.4
Mesencephalon4.24 ± 0.54
Myelencephalon4.38 ± 0.49
Occipital Lobe4.49 ± 0.55
Parietal Lobe4.4 ± 0.45
Pontine Tegmentum4.28 ± 0.51
Striatum4.33 ± 0.46
Subthalamus4.39 ± 0.16
Temporal Lobe4.44 ± 0.46
Thalamus4.46 ± 0.4
White Matter4.32 ± 0.71
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Noc2lCBCerebellum55.55
68.58
Noc2lCTXCerebral cortex99.4
79.94
Noc2lHIPHippocampal region85.55
100
Noc2lHPFHippocampal formation96.71
100
Noc2lHYHypothalamus78.92
69.14
Noc2lLSXLateral septal complex68.57
55.77
Noc2lMBMidbrain52.33
53.16
Noc2lMYMedulla54.55
64.72
Noc2lOLFOlfactory bulb100
100
Noc2lPPons52.81
62.13
Noc2lPALPallidum68.37
62.48
Noc2lRHPRetrohippocampal region100
100
Noc2lsAMYStriatum-like amygdalar nuclei100
100
Noc2lSTRStriatum100
86.16
Noc2lSTRdStriatum dorsal region100
80.25
Noc2lSTRvStriatum ventral region100
100
Noc2lTHThalamus63.75
62.07
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
NOC2L_HUMAN_11 31 11 41 LAELTVDEFLASGFDSESESESENSPQAETR PRIDE
NOC2L_HUMAN_145 12 145 156 NSVPVTVAMVER PRIDE
NOC2L_HUMAN_45 17 45 61 EAARSPDKPGGSPSASR PRIDE
NOC2L_HUMAN_666 19 666 684 DLFDLNSSEEDDTEGFSER PRIDE
PAp00008545 11 577 587 VQENSAYICSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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