AutismKB 2.0

Annotation Detail for GTPBP5


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Basic Information Top
Gene Symbol:GTPBP5 ( FLJ10741,MGC29512,ObgH1,dJ1005F21.2 )
Gene Full Name: GTP binding protein 5 (putative)
Band: 20q13.33
Quick LinksEntrez ID:26164; OMIM: 610919; Uniprot ID:GTPB5_HUMAN; ENSEMBL ID: ENSG00000101181; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst4 / 6231964
fetus30 / 56401253
neonate3 / 3109796
infant0 / 236200 
juvenile1 / 5555617
adult98 / 193912150
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor11 / 94178116
cervical tumor4 / 34366116
chondrosarcoma8 / 8282396
colorectal tumor6 / 11424652
esophageal tumor3 / 17290173
gastrointestinal tumor5 / 11936941
germ cell tumor35 / 263845132
glioma2 / 10688318
head and neck tumor13 / 13630295
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor12 / 96359124
lung tumor0 / 1031270 
lymphoma3 / 7175541
non-neoplasia6 / 9725061
normal172 / 336030751
ovarian tumor3 / 7668239
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor14 / 124949112
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder1 / 2975733
blood2 / 12347816
bone1 / 7165513
bone marrow0 / 488010 
brain67 / 110098960
cervix4 / 4817183
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus3 / 20209148
eye6 / 21105428
heart1 / 8962611
intestine17 / 23447272
kidney7 / 21177733
larynx0 / 241450 
liver17 / 20774381
lung21 / 33697462
lymph3 / 4427067
lymph node4 / 9161043
mammary gland12 / 15327178
mouth16 / 67052238
muscle13 / 107715120
nerve1 / 1576863
ovary8 / 10205178
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta11 / 28082539
prostate12 / 18934563
salivary gland0 / 201550 
skin45 / 210574213
spleen2 / 5395237
stomach1 / 9661910
testis27 / 33044281
thymus10 / 81131123
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus6 / 23287825
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P391229
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.05 ± 0.67
Basal Forebrain4.88 ± 0.25
Basal Part of Pons4.6 ± 0.44
Cerebellar Cortex4.9 ± 0.42
Cerebellar Nuclei4.73 ± 0.58
Claustrum4.96 ± 0.64
Epithalamus4.69 ± 0.28
Frontal Lobe4.64 ± 0.45
Globus Pallidus5.12 ± 0.36
Hypothalamus4.73 ± 0.36
Insula4.57 ± 0.4
Limbic Lobe4.83 ± 0.49
Mesencephalon4.85 ± 0.46
Myelencephalon4.78 ± 0.48
Occipital Lobe4.94 ± 0.5
Parietal Lobe4.73 ± 0.57
Pontine Tegmentum4.62 ± 0.51
Striatum4.87 ± 0.42
Subthalamus4.34 ± 0.61
Temporal Lobe4.74 ± 0.4
Thalamus4.72 ± 0.45
White Matter5.34 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gtpbp5CBCerebellum34.12
55.14
Gtpbp5CTXCerebral cortex48.32
36.77
Gtpbp5HIPHippocampal region56.61
89.42
Gtpbp5HPFHippocampal formation45.89
61.31
Gtpbp5HYHypothalamus22.14
18.09
Gtpbp5LSXLateral septal complex42.79
30.38
Gtpbp5MBMidbrain13.81
15.49
Gtpbp5MYMedulla6.71
7.7
Gtpbp5OLFOlfactory bulb30.01
24.87
Gtpbp5PPons5.9
6.71
Gtpbp5PALPallidum20.46
17.03
Gtpbp5RHPRetrohippocampal region27.16
22.25
Gtpbp5sAMYStriatum-like amygdalar nuclei25.66
18.79
Gtpbp5STRStriatum31.05
23.19
Gtpbp5STRdStriatum dorsal region27.29
20.56
Gtpbp5STRvStriatum ventral region43.48
30.78
Gtpbp5THThalamus25.54
21.75
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00131957 14 202 215 APVTCTPGQPGQQR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018