AutismKB 2.0

Annotation Detail for AMD1


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Basic Information Top
Gene Symbol:AMD1 ( ADOMETDC,AMD,DKFZp313L1234,FLJ26964,SAMDC )
Gene Full Name: adenosylmethionine decarboxylase 1
Band: 6q21
Quick LinksEntrez ID:262; OMIM: 180980; Uniprot ID:DCAM_HUMAN; ENSEMBL ID: ENSG00000123505; HGNC ID: 457
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body12 / 70761169
blastocyst14 / 62319224
fetus64 / 564012113
neonate10 / 31097321
infant5 / 23620211
juvenile9 / 55556161
adult313 / 1939121161
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor8 / 9417884
cervical tumor7 / 34366203
chondrosarcoma6 / 8282372
colorectal tumor8 / 11424670
esophageal tumor5 / 17290289
gastrointestinal tumor8 / 11936967
germ cell tumor49 / 263845185
glioma5 / 10688346
head and neck tumor14 / 136302102
kidney tumor11 / 68959159
leukemia8 / 9584283
liver tumor8 / 9635983
lung tumor4 / 10312738
lymphoma8 / 71755111
non-neoplasia21 / 97250215
normal714 / 3360307212
ovarian tumor3 / 7668239
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS14 / 125680111
prostate cancer50 / 102680486
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor25 / 125191199
uterine tumor14 / 90257155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites2 / 4001549
bladder2 / 2975767
blood23 / 123478186
bone13 / 71655181
bone marrow5 / 48801102
brain426 / 1100989386
cervix7 / 48171145
connective tissue17 / 149255113
ear4 / 16212246
embryonic tissue42 / 215722194
esophagus5 / 20209247
eye12 / 21105456
heart6 / 8962666
intestine22 / 23447293
kidney33 / 211777155
larynx4 / 24145165
liver18 / 20774386
lung29 / 33697486
lymph2 / 4427045
lymph node20 / 91610218
mammary gland37 / 153271241
mouth10 / 67052149
muscle15 / 107715139
nerve3 / 15768190
ovary6 / 10205158
pancreas13 / 21481260
parathyroid3 / 20539146
pharynx2 / 4132848
pituitary gland2 / 16585120
placenta86 / 280825306
prostate86 / 189345454
salivary gland2 / 2015599
skin18 / 21057485
spleen1 / 5395218
stomach8 / 9661982
testis101 / 330442305
thymus24 / 81131295
thyroid1 / 4747321
tonsil0 / 169990 
trachea57 / 524131087
umbilical cord0 / 136800 
uterus45 / 232878193
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201197_at
Cell line Expression level Expression bar
721_B_lymphoblasts362.8
Adipocyte43.55
AdrenalCortex53.05
Adrenalgland20.4
Amygdala107.65
Appendix34.3
AtrioventricularNode13.75
BDCA4+_DentriticCells249.15
Bonemarrow34.2
BronchialEpithelialCells77.05
CD105+_Endothelial520.55
CD14+_Monocytes275.85
CD19+_BCells(neg._sel.)265.35
CD33+_Myeloid184.35
CD34+446.65
CD4+_Tcells166.5
CD56+_NKCells229.9
CD71+_EarlyErythroid304.2
CD8+_Tcells171.35
CardiacMyocytes74.5
Caudatenucleus75.5
Cerebellum25.05
CerebellumPeduncles42.4
CiliaryGanglion20.75
CingulateCortex74.75
Colorectaladenocarcinoma50.05
DorsalRootGanglion29.75
FetalThyroid32.3
Fetalbrain60
Fetalliver48.6
Fetallung69.05
GlobusPallidus36.7
Heart23.1
Hypothalamus139.75
Kidney18.35
Leukemia_chronicMyelogenousK-56263.85
Leukemia_promyelocytic-HL-60116.8
Leukemialymphoblastic(MOLT-4)129.8
Liver18.55
Lung13.3
Lymphnode52.5
Lymphoma_burkitts(Daudi)125.1
Lymphoma_burkitts(Raji)69.7
MedullaOblongata78.15
OccipitalLobe141.3
OlfactoryBulb66.65
Ovary19.15
Pancreas39.1
PancreaticIslet70.05
ParietalLobe64
Pituitary69.95
Placenta169.05
Pons30.45
PrefrontalCortex192
Prostate892.65
Salivarygland42.9
SkeletalMuscle32.35
Skin38.45
SmoothMuscle52.75
Spinalcord72.55
SubthalamicNucleus45.1
SuperiorCervicalGanglion37.15
TemporalLobe47.1
Testis29.6
TestisGermCell64.35
TestisIntersitial26.1
TestisLeydigCell38.2
TestisSeminiferousTubule33.7
Thalamus49.9
Thymus33.05
Thyroid106.55
Tongue32.35
Tonsil39.35
Trachea48.45
TrigeminalGanglion58
Uterus76.8
UterusCorpus20.65
WholeBlood339.2
Wholebrain54.1
colon138.75
pineal_day171.14
pineal_night159.58
retina119.8
small_intestine118.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P214121
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala11 ± 0.18
Basal Forebrain11.03 ± 0.15
Basal Part of Pons11.08 ± 0.22
Cerebellar Cortex10.91 ± 0.24
Cerebellar Nuclei11.36 ± 0.26
Claustrum11.04 ± 0.26
Epithalamus10.76 ± 0.4
Frontal Lobe10.96 ± 0.25
Globus Pallidus11.1 ± 0.22
Hypothalamus10.89 ± 0.42
Insula10.91 ± 0.29
Limbic Lobe11.08 ± 0.33
Mesencephalon11.09 ± 0.31
Myelencephalon11.05 ± 0.31
Occipital Lobe11.52 ± 0.33
Parietal Lobe11.15 ± 0.24
Pontine Tegmentum11.15 ± 0.29
Striatum11.41 ± 0.22
Subthalamus11.26 ± 0.4
Temporal Lobe10.97 ± 0.25
Thalamus11.13 ± 0.23
White Matter12.02 ± 0.17
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
DCAM_HUMAN_21 13 21 33 QQPDANQGSGDLR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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