AutismKB 2.0

Annotation Detail for GAS8


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Basic Information Top
Gene Symbol:GAS8 ( GAS11,MGC138326 )
Gene Full Name: growth arrest-specific 8
Band: 16q24.3
Quick LinksEntrez ID:2622; OMIM: 605178; Uniprot ID:GAS8_HUMAN; ENSEMBL ID: ENSG00000141013; HGNC ID: 4166
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus12 / 56401221
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult59 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor3 / 3436687
chondrosarcoma5 / 8282360
colorectal tumor9 / 11424678
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor7 / 26384526
glioma2 / 10688318
head and neck tumor5 / 13630236
kidney tumor0 / 689590 
leukemia6 / 9584262
liver tumor0 / 963590 
lung tumor5 / 10312748
lymphoma2 / 7175527
non-neoplasia2 / 9725020
normal58 / 336030717
ovarian tumor2 / 7668226
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood6 / 12347848
bone2 / 7165527
bone marrow0 / 488010 
brain20 / 110098918
cervix3 / 4817162
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus1 / 2020949
eye7 / 21105433
heart1 / 8962611
intestine16 / 23447268
kidney2 / 2117779
larynx1 / 2414541
liver1 / 2077434
lung14 / 33697441
lymph0 / 442700 
lymph node0 / 916100 
mammary gland6 / 15327139
mouth0 / 670520 
muscle4 / 10771537
nerve0 / 157680 
ovary3 / 10205129
pancreas3 / 21481213
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate2 / 18934510
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach3 / 9661931
testis10 / 33044230
thymus2 / 8113124
thyroid4 / 4747384
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204921_at
Cell line Expression level Expression bar
721_B_lymphoblasts74.3
Adipocyte65.5
AdrenalCortex71.1
Adrenalgland64.2
Amygdala70.4
Appendix71.9
AtrioventricularNode62.95
BDCA4+_DentriticCells33.2
Bonemarrow93.2
BronchialEpithelialCells60.6
CD105+_Endothelial59.35
CD14+_Monocytes65.7
CD19+_BCells(neg._sel.)55.7
CD33+_Myeloid57.35
CD34+49.55
CD4+_Tcells67.9
CD56+_NKCells72.3
CD71+_EarlyErythroid60.35
CD8+_Tcells58.4
CardiacMyocytes77.7
Caudatenucleus59.7
Cerebellum64.05
CerebellumPeduncles89.1
CiliaryGanglion50
CingulateCortex87.75
Colorectaladenocarcinoma75.7
DorsalRootGanglion67.7
FetalThyroid87.95
Fetalbrain82.3
Fetalliver66.75
Fetallung53.8
GlobusPallidus49.4
Heart86.9
Hypothalamus85.85
Kidney59.55
Leukemia_chronicMyelogenousK-56265.35
Leukemia_promyelocytic-HL-6058.75
Leukemialymphoblastic(MOLT-4)54.45
Liver91.85
Lung96.9
Lymphnode71.15
Lymphoma_burkitts(Daudi)85
Lymphoma_burkitts(Raji)99.2
MedullaOblongata60.7
OccipitalLobe58.55
OlfactoryBulb56.85
Ovary74.05
Pancreas54.75
PancreaticIslet85.5
ParietalLobe88.6
Pituitary78.8
Placenta64.7
Pons65.05
PrefrontalCortex92.8
Prostate79.2
Salivarygland57.05
SkeletalMuscle88.75
Skin57.5
SmoothMuscle66.8
Spinalcord70.7
SubthalamicNucleus61.15
SuperiorCervicalGanglion86.7
TemporalLobe63.85
Testis83.5
TestisGermCell61.75
TestisIntersitial64.85
TestisLeydigCell70.9
TestisSeminiferousTubule66.85
Thalamus67.7
Thymus52.95
Thyroid94.2
Tongue67.75
Tonsil70.95
Trachea61
TrigeminalGanglion77.5
Uterus54
UterusCorpus64.05
WholeBlood69.6
Wholebrain57.55
colon66.8
pineal_day79.6
pineal_night75.38
retina85.55
small_intestine63.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P279203
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.73 ± 1.1
Basal Forebrain2.22 ± 0.25
Basal Part of Pons2.68 ± 0.8
Cerebellar Cortex2.85 ± 0.5
Cerebellar Nuclei2.68 ± 0.66
Claustrum2.45 ± 0.68
Epithalamus2.77 ± 0.79
Frontal Lobe2.54 ± 0.78
Globus Pallidus2.27 ± 0.44
Hypothalamus2.46 ± 1.05
Insula2.85 ± 0.67
Limbic Lobe2.48 ± 0.67
Mesencephalon2.56 ± 0.71
Myelencephalon2.46 ± 0.7
Occipital Lobe2.81 ± 0.72
Parietal Lobe2.59 ± 0.67
Pontine Tegmentum2.48 ± 0.66
Striatum1.87 ± 0.73
Subthalamus2.48 ± 0.64
Temporal Lobe2.39 ± 0.78
Thalamus2.49 ± 0.72
White Matter1.57 ± 0.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gas8CBCerebellum36.48
54.07
Gas8CTXCerebral cortex100
76.19
Gas8HIPHippocampal region59.6
57.05
Gas8HPFHippocampal formation86.34
62.81
Gas8HYHypothalamus86.76
39.36
Gas8LSXLateral septal complex90.58
41.39
Gas8MBMidbrain63.56
33.3
Gas8MYMedulla72.07
47.8
Gas8OLFOlfactory bulb100
62.7
Gas8PPons69.62
45.02
Gas8PALPallidum81.29
44.78
Gas8RHPRetrohippocampal region100
76.87
Gas8sAMYStriatum-like amygdalar nuclei100
43.84
Gas8STRStriatum85.15
33.61
Gas8STRdStriatum dorsal region75.93
29.66
Gas8STRvStriatum ventral region100
38.91
Gas8THThalamus100
63.8
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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