AutismKB 2.0

Annotation Detail for GATA3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GATA3 ( HDR,MGC2346,MGC5199,MGC5445 )
Gene Full Name: GATA binding protein 3
Band: 10p14
Quick LinksEntrez ID:2625; OMIM: 131320; Uniprot ID:GATA3_HUMAN; ENSEMBL ID: ENSG00000107485; HGNC ID: 4172
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst0 / 623190 
fetus27 / 56401247
neonate0 / 310970 
infant2 / 2362084
juvenile5 / 5555689
adult95 / 193912148
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor22 / 94178233
cervical tumor2 / 3436658
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor8 / 26384530
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia6 / 9584262
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal129 / 336030738
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS16 / 125680127
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites0 / 400150 
bladder7 / 29757235
blood8 / 12347864
bone0 / 716550 
bone marrow0 / 488010 
brain9 / 11009898
cervix2 / 4817141
connective tissue0 / 1492550 
ear6 / 16212370
embryonic tissue19 / 21572288
esophagus0 / 202090 
eye5 / 21105423
heart2 / 8962622
intestine0 / 2344720 
kidney4 / 21177718
larynx0 / 241450 
liver3 / 20774314
lung1 / 3369742
lymph0 / 442700 
lymph node1 / 9161010
mammary gland24 / 153271156
mouth1 / 6705214
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid5 / 20539243
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta52 / 280825185
prostate5 / 18934526
salivary gland0 / 201550 
skin8 / 21057437
spleen0 / 539520 
stomach1 / 9661910
testis0 / 3304420 
thymus2 / 8113124
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209603_at
Cell line Expression level Expression bar
721_B_lymphoblasts8
Adipocyte6.1
AdrenalCortex7
Adrenalgland5.5
Amygdala6.4
Appendix6.95
AtrioventricularNode5.35
BDCA4+_DentriticCells6.4
Bonemarrow6.45
BronchialEpithelialCells6.05
CD105+_Endothelial6.2
CD14+_Monocytes6.6
CD19+_BCells(neg._sel.)6.65
CD33+_Myeloid7.9
CD34+8.8
CD4+_Tcells11.3
CD56+_NKCells31.15
CD71+_EarlyErythroid6
CD8+_Tcells8.35
CardiacMyocytes8.9
Caudatenucleus5.6
Cerebellum5.05
CerebellumPeduncles7.35
CiliaryGanglion4.85
CingulateCortex6.55
Colorectaladenocarcinoma6.25
DorsalRootGanglion5.15
FetalThyroid6.1
Fetalbrain6
Fetalliver5.4
Fetallung4.8
GlobusPallidus4.8
Heart8
Hypothalamus6.65
Kidney5.15
Leukemia_chronicMyelogenousK-5625.65
Leukemia_promyelocytic-HL-605.5
Leukemialymphoblastic(MOLT-4)17.25
Liver8.95
Lung6.8
Lymphnode5.25
Lymphoma_burkitts(Daudi)8.2
Lymphoma_burkitts(Raji)9.25
MedullaOblongata5.7
OccipitalLobe5.6
OlfactoryBulb4.9
Ovary4.3
Pancreas5
PancreaticIslet6.7
ParietalLobe6.85
Pituitary7.3
Placenta70.4
Pons6
PrefrontalCortex7.55
Prostate7.3
Salivarygland5.15
SkeletalMuscle7.95
Skin5.45
SmoothMuscle6.95
Spinalcord6.7
SubthalamicNucleus5.8
SuperiorCervicalGanglion8.55
TemporalLobe5.75
Testis5.4
TestisGermCell5.15
TestisIntersitial5.3
TestisLeydigCell6.4
TestisSeminiferousTubule5.3
Thalamus6.4
Thymus7.05
Thyroid8
Tongue6.3
Tonsil6.1
Trachea5.2
TrigeminalGanglion7.05
Uterus5
UterusCorpus5.85
WholeBlood6.95
Wholebrain5.2
colon6.3
pineal_day7.72
pineal_night7.56
retina7.575
small_intestine6.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15960_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.53 ± 1.15
Basal Forebrain2.75 ± 0.68
Basal Part of Pons1.88 ± 0.54
Cerebellar Cortex3.4 ± 1.19
Cerebellar Nuclei3.53 ± 1.38
Claustrum4.26 ± 1.44
Epithalamus3.13 ± 0.91
Frontal Lobe3.14 ± 1.21
Globus Pallidus4.64 ± 1.32
Hypothalamus3 ± 0.52
Insula3.26 ± 1.18
Limbic Lobe2.92 ± 1.07
Mesencephalon4.85 ± 1.22
Myelencephalon3.64 ± 1.3
Occipital Lobe3.84 ± 1.33
Parietal Lobe3.64 ± 1.37
Pontine Tegmentum3.84 ± 1.22
Striatum3.71 ± 1.07
Subthalamus3.6 ± 0.57
Temporal Lobe3.49 ± 1.39
Thalamus5.35 ± 1.14
White Matter4 ± 0.79
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gata3CBCerebellum8.84
11.29
Gata3CTXCerebral cortex0.8
0.9
Gata3HIPHippocampal region0.84
1.05
Gata3HPFHippocampal formation0.68
0.79
Gata3HYHypothalamus0.12
0.12
Gata3LSXLateral septal complex0.29
0.86
Gata3MBMidbrain5.16
5.11
Gata3MYMedulla2.33
3.63
Gata3OLFOlfactory bulb2.27
1.81
Gata3PPons4.02
4.6
Gata3PALPallidum0.22
0.22
Gata3RHPRetrohippocampal region0.53
0.56
Gata3sAMYStriatum-like amygdalar nuclei0.21
0.16
Gata3STRStriatum0.61
0.57
Gata3STRdStriatum dorsal region0.25
0.3
Gata3STRvStriatum ventral region2.03
1.43
Gata3THThalamus0.69
0.7
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00095539 16 277 292 DGTGHYLCNACGLYHK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved