Annotation Detail for GATA4
Basic Information Top
| Gene Symbol: | GATA4 ( MGC126629 ) |
|---|---|
| Gene Full Name: | GATA binding protein 4 |
| Band: | 8p23.1 |
| Quick Links | Entrez ID:2626; OMIM: 600576; Uniprot ID:GATA4_HUMAN; ENSEMBL ID: ENSG00000136574; HGNC ID: 4173 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.243987
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 4 / 70761 | 56 |  |
| blastocyst | 6 / 62319 | 96 | |
| fetus | 21 / 564012 | 37 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 34 / 1939121 | 17 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 4 / 119369 | 33 | |
| germ cell tumor | 4 / 263845 | 15 | |
| glioma | 1 / 106883 | 9 |  |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 6 / 96359 | 62 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 70 / 3360307 | 20 | |
| ovarian tumor | 10 / 76682 | 130 | |
| pancreatic tumor | 4 / 104616 | 38 | |
| primitive neuroectodermal tumor of the CNS | 2 / 125680 | 15 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 8 / 125191 | 63 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 8 / 1100989 | 7 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 8 / 149255 | 53 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 10 / 215722 | 46 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 3 / 211054 | 14 | |
| heart | 3 / 89626 | 33 | |
| intestine | 3 / 234472 | 12 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 8 / 207743 | 38 | |
| lung | 4 / 336974 | 11 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 11 / 102051 | 107 | |
| pancreas | 13 / 214812 | 60 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 4 / 280825 | 14 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 1 / 210574 | 4 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 6 / 96619 | 62 | |
| testis | 12 / 330442 | 36 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 205517_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 9.65 | |
| Adipocyte | 8.35 | |
| AdrenalCortex | 14.8 | |
| Adrenalgland | 8.6 | |
| Amygdala | 9.05 | |
| Appendix | 12.6 | |
| AtrioventricularNode | 11.3 | |
| BDCA4+_DentriticCells | 8.8 | |
| Bonemarrow | 10.95 | |
| BronchialEpithelialCells | 8.4 | |
| CD105+_Endothelial | 9.05 | |
| CD14+_Monocytes | 9.7 | |
| CD19+_BCells(neg._sel.) | 9.45 | |
| CD33+_Myeloid | 11.1 | |
| CD34+ | 11.55 | |
| CD4+_Tcells | 8.95 | |
| CD56+_NKCells | 9.45 | |
| CD71+_EarlyErythroid | 11.7 | |
| CD8+_Tcells | 7.75 | |
| CardiacMyocytes | 38.3 | |
| Caudatenucleus | 8.05 | |
| Cerebellum | 7.7 | |
| CerebellumPeduncles | 11.2 | |
| CiliaryGanglion | 8.05 | |
| CingulateCortex | 9.9 | |
| Colorectaladenocarcinoma | 9.25 | |
| DorsalRootGanglion | 11.05 | |
| FetalThyroid | 9.4 | |
| Fetalbrain | 8.45 | |
| Fetalliver | 8.6 | |
| Fetallung | 6.6 | |
| GlobusPallidus | 7.8 | |
| Heart | 223.8 |  |
| Hypothalamus | 8.85 | |
| Kidney | 8.2 | |
| Leukemia_chronicMyelogenousK-562 | 8.5 | |
| Leukemia_promyelocytic-HL-60 | 8.2 | |
| Leukemialymphoblastic(MOLT-4) | 6.55 | |
| Liver | 18.75 | |
| Lung | 10 | |
| Lymphnode | 7.5 | |
| Lymphoma_burkitts(Daudi) | 12.6 | |
| Lymphoma_burkitts(Raji) | 15.4 | |
| MedullaOblongata | 7.95 | |
| OccipitalLobe | 8.25 | |
| OlfactoryBulb | 6.85 | |
| Ovary | 7.15 | |
| Pancreas | 23.6 | |
| PancreaticIslet | 12.1 | |
| ParietalLobe | 10.15 | |
| Pituitary | 10.85 | |
| Placenta | 9.55 | |
| Pons | 9.2 | |
| PrefrontalCortex | 10.2 | |
| Prostate | 10.35 | |
| Salivarygland | 8.05 | |
| SkeletalMuscle | 15.4 | |
| Skin | 10.45 | |
| SmoothMuscle | 18.3 | |
| Spinalcord | 10.05 | |
| SubthalamicNucleus | 8.75 | |
| SuperiorCervicalGanglion | 14.85 | |
| TemporalLobe | 8.9 | |
| Testis | 41.75 | |
| TestisGermCell | 43.1 | |
| TestisIntersitial | 9 | |
| TestisLeydigCell | 9.9 | |
| TestisSeminiferousTubule | 23.45 | |
| Thalamus | 9.85 | |
| Thymus | 6.7 | |
| Thyroid | 10.5 | |
| Tongue | 13.25 | |
| Tonsil | 9.35 | |
| Trachea | 7.65 | |
| TrigeminalGanglion | 13.8 | |
| Uterus | 7 | |
| UterusCorpus | 10.15 | |
| WholeBlood | 9.1 | |
| Wholebrain | 6.65 | |
| colon | 9 | |
| pineal_day | 10.66 | |
| pineal_night | 10.52 | |
| retina | 10.625 | |
| small_intestine | 54.7 | |
- Probe name: CUST_16483_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.51 ± 1.11 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 2.96 ± 0.49 | |
| Basal Part of Pons | 2.79 ± 0.86 | |
| Cerebellar Cortex | 2.88 ± 0.83 | |
| Cerebellar Nuclei | 3.27 ± 0.9 | |
| Claustrum | 4 ± 0.92 | |
| Epithalamus | 2.6 ± 0.95 | |
| Frontal Lobe | 2.88 ± 0.87 | |
| Globus Pallidus | 3.44 ± 0.55 | |
| Hypothalamus | 3.04 ± 0.94 | |
| Insula | 2.82 ± 0.91 | |
| Limbic Lobe | 3.11 ± 0.93 | |
| Mesencephalon | 3.15 ± 1.02 | |
| Myelencephalon | 3.13 ± 0.92 | |
| Occipital Lobe | 3.12 ± 0.91 | |
| Parietal Lobe | 3.11 ± 1 | |
| Pontine Tegmentum | 3.13 ± 0.93 | |
| Striatum | 3.38 ± 0.99 | |
| Subthalamus | 2.95 ± 1.33 | |
| Temporal Lobe | 2.99 ± 0.95 | |
| Thalamus | 3.02 ± 0.62 | |
| White Matter | 3.97 ± 0.84 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Gata4 | CB | Cerebellum | 14.63 | |
| 23.81 | | |||
| Gata4 | CTX | Cerebral cortex | 3.03 | |
| 2.13 | | |||
| Gata4 | HIP | Hippocampal region | 1.86 | |
| 1.71 | | |||
| Gata4 | HPF | Hippocampal formation | 3.77 | |
| 3.2 | | |||
| Gata4 | HY | Hypothalamus | 0.13 | |
| 0.11 | | |||
| Gata4 | LSX | Lateral septal complex | 0.25 | |
| 0.24 | | |||
| Gata4 | MB | Midbrain | 0.43 | |
| 0.47 | | |||
| Gata4 | MY | Medulla | 1.8 | |
| 2.18 | | |||
| Gata4 | OLF | Olfactory bulb | 7.88 | |
| 6.7 | | |||
| Gata4 | P | Pons | 1.05 | |
| 1.5 | | |||
| Gata4 | PAL | Pallidum | 1.48 | |
| 1.09 | | |||
| Gata4 | RHP | Retrohippocampal region | 6.56 | |
| 4.8 | | |||
| Gata4 | sAMY | Striatum-like amygdalar nuclei | 8.46 | |
| 5.08 | | |||
| Gata4 | STR | Striatum | 5.88 | |
| 4.12 | | |||
| Gata4 | STRd | Striatum dorsal region | 5.32 | |
| 3.62 | | |||
| Gata4 | STRv | Striatum ventral region | 8.61 | |
| 6.82 | | |||
| Gata4 | TH | Thalamus | 0.76 | |
| 0.59 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| GATA4_HUMAN_300 | 18 | 300 | 317 | LHGVPRPLAMRKEGIQTR | PRIDE |
| PAp00095539 | 16 | 231 | 246 | DGTGHYLCNACGLYHK | Peptide Atlas |