AutismKB 2.0

Annotation Detail for FBXO25


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Basic Information Top
Gene Symbol:FBXO25 ( FBX25,MGC20256,MGC51975 )
Gene Full Name: F-box protein 25
Band: 8p23.3
Quick LinksEntrez ID:26260; OMIM: 609098; Uniprot ID:FBX25_HUMAN; ENSEMBL ID: ENSG00000147364; HGNC ID: 13596
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus29 / 56401251
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult61 / 193912131
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor8 / 26384530
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia6 / 9584262
liver tumor2 / 9635920
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal105 / 336030731
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer13 / 102680126
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites3 / 4001574
bladder0 / 297570 
blood4 / 12347832
bone3 / 7165541
bone marrow0 / 488010 
brain16 / 110098914
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye8 / 21105437
heart0 / 896260 
intestine8 / 23447234
kidney15 / 21177770
larynx0 / 241450 
liver6 / 20774328
lung10 / 33697429
lymph0 / 442700 
lymph node6 / 9161065
mammary gland2 / 15327113
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary2 / 10205119
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta10 / 28082535
prostate19 / 189345100
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach1 / 9661910
testis25 / 33044275
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_182_PI417507815
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.99 ± 0.17
Basal Forebrain11.15 ± 0.12
Basal Part of Pons10.94 ± 0.14
Cerebellar Cortex11.25 ± 0.14
Cerebellar Nuclei11.12 ± 0.14
Claustrum11.13 ± 0.17
Epithalamus11.04 ± 0.21
Frontal Lobe11.01 ± 0.24
Globus Pallidus10.88 ± 0.12
Hypothalamus11.14 ± 0.13
Insula10.96 ± 0.24
Limbic Lobe11.02 ± 0.26
Mesencephalon11.05 ± 0.18
Myelencephalon10.98 ± 0.2
Occipital Lobe11.09 ± 0.21
Parietal Lobe11.04 ± 0.19
Pontine Tegmentum11.1 ± 0.24
Striatum11.06 ± 0.25
Subthalamus11.25 ± 0.24
Temporal Lobe11.01 ± 0.2
Thalamus10.83 ± 0.17
White Matter11.64 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fbxo25CBCerebellum9.41
9.78
Fbxo25CTXCerebral cortex73.96
58.77
Fbxo25HIPHippocampal region61.46
100
Fbxo25HPFHippocampal formation56.92
74.88
Fbxo25HYHypothalamus38.22
33.69
Fbxo25LSXLateral septal complex44.88
34.43
Fbxo25MBMidbrain42.61
39.05
Fbxo25MYMedulla18.17
17.44
Fbxo25OLFOlfactory bulb64.24
57.54
Fbxo25PPons30.83
32.14
Fbxo25PALPallidum37.87
36.73
Fbxo25RHPRetrohippocampal region50.84
43.92
Fbxo25sAMYStriatum-like amygdalar nuclei54.84
43.74
Fbxo25STRStriatum62.72
48.28
Fbxo25STRdStriatum dorsal region65.34
50.34
Fbxo25STRvStriatum ventral region63.25
47.87
Fbxo25THThalamus30.36
25.85
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018