AutismKB 2.0

Annotation Detail for FBXO24


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Basic Information Top
Gene Symbol:FBXO24 ( DKFZp434I1122,FBX24 )
Gene Full Name: F-box protein 24
Band: 7q22.1
Quick LinksEntrez ID:26261; OMIM: 609097; Uniprot ID:FBX24_HUMAN; ENSEMBL ID: ENSG00000106336; HGNC ID: 13595
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult7 / 19391213
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal50 / 336030714
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone0 / 716550 
bone marrow0 / 488010 
brain5 / 11009894
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node5 / 9161054
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis45 / 330442136
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221157_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.8
Adipocyte4.85
AdrenalCortex5.4
Adrenalgland4.5
Amygdala5.1
Appendix4.95
AtrioventricularNode4.15
BDCA4+_DentriticCells5
Bonemarrow5.2
BronchialEpithelialCells4.8
CD105+_Endothelial4.85
CD14+_Monocytes5.15
CD19+_BCells(neg._sel.)5.1
CD33+_Myeloid6.3
CD34+6.05
CD4+_Tcells5.35
CD56+_NKCells5.55
CD71+_EarlyErythroid4.55
CD8+_Tcells4.55
CardiacMyocytes6.85
Caudatenucleus4.4
Cerebellum4.4
CerebellumPeduncles5.65
CiliaryGanglion4.2
CingulateCortex5.15
Colorectaladenocarcinoma5
DorsalRootGanglion4.05
FetalThyroid4.8
Fetalbrain4.85
Fetalliver4.35
Fetallung4
GlobusPallidus3.7
Heart6.6
Hypothalamus5.2
Kidney4.1
Leukemia_chronicMyelogenousK-5624.45
Leukemia_promyelocytic-HL-604.85
Leukemialymphoblastic(MOLT-4)3.95
Liver6.55
Lung5.35
Lymphnode4.1
Lymphoma_burkitts(Daudi)6.4
Lymphoma_burkitts(Raji)7
MedullaOblongata4.45
OccipitalLobe5.65
OlfactoryBulb3.85
Ovary3.35
Pancreas3.9
PancreaticIslet5.25
ParietalLobe5.35
Pituitary6.1
Placenta5.05
Pons7
PrefrontalCortex6
Prostate5.65
Salivarygland4.2
SkeletalMuscle6.2
Skin4.3
SmoothMuscle5.55
Spinalcord5.55
SubthalamicNucleus5.9
SuperiorCervicalGanglion5.85
TemporalLobe4.45
Testis45.5
TestisGermCell26
TestisIntersitial18.3
TestisLeydigCell8.7
TestisSeminiferousTubule25.45
Thalamus5.15
Thymus3.8
Thyroid6.05
Tongue4.95
Tonsil4.8
Trachea4.2
TrigeminalGanglion5.1
Uterus3.95
UterusCorpus4.45
WholeBlood5.15
Wholebrain4.1
colon4.95
pineal_day6.06
pineal_night5.98
retina6.4
small_intestine4.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_717_PI416573500
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.19 ± 0.84
Basal Forebrain1.98 ± 0.46
Basal Part of Pons2.1 ± 0.6
Cerebellar Cortex1.88 ± 0.79
Cerebellar Nuclei2.23 ± 0.68
Claustrum2.47 ± 0.56
Epithalamus1.66 ± 0.59
Frontal Lobe1.93 ± 0.85
Globus Pallidus2.57 ± 0.5
Hypothalamus1.98 ± 0.45
Insula1.57 ± 0.6
Limbic Lobe2.05 ± 0.82
Mesencephalon1.98 ± 0.73
Myelencephalon2.14 ± 0.78
Occipital Lobe2.06 ± 0.9
Parietal Lobe2.01 ± 0.8
Pontine Tegmentum1.87 ± 0.8
Striatum2.07 ± 0.79
Subthalamus1.98 ± 0.23
Temporal Lobe2.02 ± 0.83
Thalamus2.13 ± 0.71
White Matter3.03 ± 0.61
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018