AutismKB 2.0

Annotation Detail for TSPAN17


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Basic Information Top
Gene Symbol:TSPAN17 ( FBX23,FBXO23,MGC14859,MGC71255,TM4SF17 )
Gene Full Name: tetraspanin 17
Band: 5q35.2
Quick LinksEntrez ID:26262; OMIM: NA; Uniprot ID:TSN17_HUMAN; ENSEMBL ID: ENSG00000048140; HGNC ID: 13594
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus10 / 56401217
neonate0 / 310970 
infant2 / 2362084
juvenile2 / 5555635
adult87 / 193912144
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1344_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.69 ± 0.78
Basal Forebrain3.18 ± 0.44
Basal Part of Pons3.44 ± 0.76
Cerebellar Cortex3.77 ± 0.46
Cerebellar Nuclei3.31 ± 0.58
Claustrum3.68 ± 0.58
Epithalamus3.05 ± 0.68
Frontal Lobe3.49 ± 0.59
Globus Pallidus2.31 ± 0.44
Hypothalamus3.12 ± 0.46
Insula3.51 ± 0.33
Limbic Lobe3.4 ± 0.63
Mesencephalon3.42 ± 0.71
Myelencephalon3.32 ± 0.58
Occipital Lobe3.33 ± 0.65
Parietal Lobe3.34 ± 0.55
Pontine Tegmentum3.3 ± 0.57
Striatum2.51 ± 0.76
Subthalamus3.69 ± 0.29
Temporal Lobe3.61 ± 0.5
Thalamus3.25 ± 0.65
White Matter2.4 ± 0.58
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tspan17CBCerebellum7.56
7.67
Tspan17CTXCerebral cortex47.88
18.49
Tspan17HIPHippocampal region12.36
10.58
Tspan17HPFHippocampal formation11.11
7.47
Tspan17HYHypothalamus15.01
4.96
Tspan17LSXLateral septal complex0.27
0.12
Tspan17MBMidbrain14.56
7.18
Tspan17MYMedulla34.81
22.46
Tspan17OLFOlfactory bulb15.37
7.73
Tspan17PPons32.8
19.36
Tspan17PALPallidum14.77
6.75
Tspan17RHPRetrohippocampal region9.26
3.27
Tspan17sAMYStriatum-like amygdalar nuclei3.59
1.54
Tspan17STRStriatum3.63
1.71
Tspan17STRdStriatum dorsal region4.23
2.13
Tspan17STRvStriatum ventral region2.91
1.06
Tspan17THThalamus16.77
6.27
Peptide Top

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018