AutismKB 2.0

Annotation Detail for TSPAN17


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Basic Information Top
Gene Symbol:TSPAN17 ( FBX23,FBXO23,MGC14859,MGC71255,TM4SF17 )
Gene Full Name: tetraspanin 17
Band: 5q35.2
Quick LinksEntrez ID:26262; OMIM: NA; Uniprot ID:TSN17_HUMAN; ENSEMBL ID: ENSG00000048140; HGNC ID: 13594
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus10 / 56401217
neonate0 / 310970 
infant2 / 2362084
juvenile2 / 5555635
adult87 / 193912144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor11 / 94178116
cervical tumor1 / 3436629
chondrosarcoma10 / 82823120
colorectal tumor1 / 1142468
esophageal tumor2 / 17290115
gastrointestinal tumor7 / 11936958
germ cell tumor9 / 26384534
glioma4 / 10688337
head and neck tumor17 / 136302124
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor8 / 10312777
lymphoma2 / 7175527
non-neoplasia2 / 9725020
normal72 / 336030721
ovarian tumor4 / 7668252
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor16 / 124949128
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone10 / 71655139
bone marrow2 / 4880140
brain20 / 110098918
cervix6 / 48171124
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus2 / 2020998
eye13 / 21105461
heart0 / 896260 
intestine8 / 23447234
kidney6 / 21177728
larynx0 / 241450 
liver1 / 2077434
lung23 / 33697468
lymph0 / 442700 
lymph node0 / 916100 
mammary gland13 / 15327184
mouth15 / 67052223
muscle4 / 10771537
nerve0 / 157680 
ovary4 / 10205139
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate4 / 18934521
salivary gland1 / 2015549
skin17 / 21057480
spleen0 / 539520 
stomach3 / 9661931
testis5 / 33044215
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1344_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.69 ± 0.78
Basal Forebrain3.18 ± 0.44
Basal Part of Pons3.44 ± 0.76
Cerebellar Cortex3.77 ± 0.46
Cerebellar Nuclei3.31 ± 0.58
Claustrum3.68 ± 0.58
Epithalamus3.05 ± 0.68
Frontal Lobe3.49 ± 0.59
Globus Pallidus2.31 ± 0.44
Hypothalamus3.12 ± 0.46
Insula3.51 ± 0.33
Limbic Lobe3.4 ± 0.63
Mesencephalon3.42 ± 0.71
Myelencephalon3.32 ± 0.58
Occipital Lobe3.33 ± 0.65
Parietal Lobe3.34 ± 0.55
Pontine Tegmentum3.3 ± 0.57
Striatum2.51 ± 0.76
Subthalamus3.69 ± 0.29
Temporal Lobe3.61 ± 0.5
Thalamus3.25 ± 0.65
White Matter2.4 ± 0.58
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tspan17CBCerebellum7.56
7.67
Tspan17CTXCerebral cortex47.88
18.49
Tspan17HIPHippocampal region12.36
10.58
Tspan17HPFHippocampal formation11.11
7.47
Tspan17HYHypothalamus15.01
4.96
Tspan17LSXLateral septal complex0.27
0.12
Tspan17MBMidbrain14.56
7.18
Tspan17MYMedulla34.81
22.46
Tspan17OLFOlfactory bulb15.37
7.73
Tspan17PPons32.8
19.36
Tspan17PALPallidum14.77
6.75
Tspan17RHPRetrohippocampal region9.26
3.27
Tspan17sAMYStriatum-like amygdalar nuclei3.59
1.54
Tspan17STRStriatum3.63
1.71
Tspan17STRdStriatum dorsal region4.23
2.13
Tspan17STRvStriatum ventral region2.91
1.06
Tspan17THThalamus16.77
6.27
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018