Annotation Detail for FBXO22
Basic Information Top
| Gene Symbol: | FBXO22 ( FBX22,FISTC1,FLJ13986,MGC31799 ) |
|---|---|
| Gene Full Name: | F-box protein 22 |
| Band: | 15q24.2 |
| Quick Links | Entrez ID:26263; OMIM: 609096; Uniprot ID:FBX22_HUMAN; ENSEMBL ID: ENSG00000167196; HGNC ID: 13593 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.591115
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 4 / 70761 | 56 |  |
| blastocyst | 5 / 62319 | 80 | |
| fetus | 21 / 564012 | 37 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 3 / 55556 | 53 | |
| adult | 49 / 1939121 | 25 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 3 / 17475 | 171 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 4 / 82823 | 48 | |
| colorectal tumor | 3 / 114246 | 26 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 |  |
| germ cell tumor | 14 / 263845 | 53 | |
| glioma | 3 / 106883 | 28 | |
| head and neck tumor | 3 / 136302 | 22 | |
| kidney tumor | 5 / 68959 | 72 | |
| leukemia | 11 / 95842 | 114 | |
| liver tumor | 1 / 96359 | 10 | |
| lung tumor | 5 / 103127 | 48 | |
| lymphoma | 7 / 71755 | 97 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 105 / 3360307 | 31 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 8 / 125680 | 63 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 10 / 46356 | 215 |  |
| skin tumor | 5 / 124949 | 40 | |
| soft tissue/muscle tissue tumor | 5 / 125191 | 39 | |
| uterine tumor | 6 / 90257 | 66 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 2 / 33197 | 60 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 3 / 29757 | 100 | |
| blood | 5 / 123478 | 40 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 7 / 48801 | 143 | |
| brain | 41 / 1100989 | 37 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 14 / 215722 | 64 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 16 / 211054 | 75 | |
| heart | 1 / 89626 | 11 | |
| intestine | 3 / 234472 | 12 | |
| kidney | 11 / 211777 | 51 | |
| larynx | 0 / 24145 | 0 | |
| liver | 5 / 207743 | 24 | |
| lung | 18 / 336974 | 53 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 2 / 91610 | 21 | |
| mammary gland | 8 / 153271 | 52 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 4 / 107715 | 37 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 2 / 102051 | 19 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 2 / 20539 | 97 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 16 / 280825 | 56 | |
| prostate | 1 / 189345 | 5 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 5 / 210574 | 23 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 8 / 330442 | 24 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 11 / 232878 | 47 | |
| vascular | 3 / 51780 | 57 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 219638_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 5.95 | |
| Adipocyte | 5.1 | |
| AdrenalCortex | 5.55 | |
| Adrenalgland | 4.4 | |
| Amygdala | 5.3 | |
| Appendix | 5.5 | |
| AtrioventricularNode | 4.65 | |
| BDCA4+_DentriticCells | 5.55 | |
| Bonemarrow | 5.3 | |
| BronchialEpithelialCells | 5.05 | |
| CD105+_Endothelial | 5.15 | |
| CD14+_Monocytes | 5.6 | |
| CD19+_BCells(neg._sel.) | 5.3 | |
| CD33+_Myeloid | 6.35 | |
| CD34+ | 6.55 | |
| CD4+_Tcells | 5.5 | |
| CD56+_NKCells | 6.05 | |
| CD71+_EarlyErythroid | 4.85 | |
| CD8+_Tcells | 4.85 | |
| CardiacMyocytes | 6.85 | |
| Caudatenucleus | 4.65 | |
| Cerebellum | 4.15 | |
| CerebellumPeduncles | 6 | |
| CiliaryGanglion | 3.95 | |
| CingulateCortex | 5.3 | |
| Colorectaladenocarcinoma | 5.15 | |
| DorsalRootGanglion | 4.2 | |
| FetalThyroid | 5.1 | |
| Fetalbrain | 5.1 | |
| Fetalliver | 4.5 | |
| Fetallung | 4.25 | |
| GlobusPallidus | 3.95 | |
| Heart | 6.75 | |
| Hypothalamus | 5.4 | |
| Kidney | 4.3 | |
| Leukemia_chronicMyelogenousK-562 | 4.65 | |
| Leukemia_promyelocytic-HL-60 | 4.55 | |
| Leukemialymphoblastic(MOLT-4) | 4.15 | |
| Liver | 7 | |
| Lung | 5.55 | |
| Lymphnode | 4.4 | |
| Lymphoma_burkitts(Daudi) | 6.85 | |
| Lymphoma_burkitts(Raji) | 7.4 | |
| MedullaOblongata | 4.65 | |
| OccipitalLobe | 4.6 | |
| OlfactoryBulb | 4.05 | |
| Ovary | 3.65 | |
| Pancreas | 4.25 | |
| PancreaticIslet | 5.55 | |
| ParietalLobe | 5.55 | |
| Pituitary | 6.05 | |
| Placenta | 5.1 | |
| Pons | 5 | |
| PrefrontalCortex | 6.2 | |
| Prostate | 5.9 | |
| Salivarygland | 4.2 | |
| SkeletalMuscle | 6.4 | |
| Skin | 4.25 | |
| SmoothMuscle | 5.75 | |
| Spinalcord | 5.5 | |
| SubthalamicNucleus | 4.75 | |
| SuperiorCervicalGanglion | 6.85 | |
| TemporalLobe | 4.7 | |
| Testis | 4.4 | |
| TestisGermCell | 4.3 | |
| TestisIntersitial | 4.45 | |
| TestisLeydigCell | 5.25 | |
| TestisSeminiferousTubule | 4.4 | |
| Thalamus | 5.25 | |
| Thymus | 3.95 | |
| Thyroid | 6.3 | |
| Tongue | 5.25 | |
| Tonsil | 5.05 | |
| Trachea | 4.3 | |
| TrigeminalGanglion | 5.3 | |
| Uterus | 4.1 | |
| UterusCorpus | 4.8 | |
| WholeBlood | 5.65 | |
| Wholebrain | 4.2 | |
| colon | 5.15 | |
| pineal_day | 6.3 | |
| pineal_night | 6.2 | |
| retina | 6.175 | |
| small_intestine | 4.95 | |
- Probe name: CUST_7491_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 7.08 ± 0.29 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 7.11 ± 0.03 | |
| Basal Part of Pons | 7.21 ± 0.13 | |
| Cerebellar Cortex | 7.37 ± 0.16 | |
| Cerebellar Nuclei | 7.29 ± 0.16 | |
| Claustrum | 6.97 ± 0.39 | |
| Epithalamus | 7.12 ± 0.35 | |
| Frontal Lobe | 7.05 ± 0.28 | |
| Globus Pallidus | 7.15 ± 0.17 | |
| Hypothalamus | 7.26 ± 0.23 | |
| Insula | 7.13 ± 0.22 | |
| Limbic Lobe | 7.18 ± 0.29 | |
| Mesencephalon | 7.23 ± 0.3 | |
| Myelencephalon | 7.12 ± 0.27 | |
| Occipital Lobe | 7.38 ± 0.24 | |
| Parietal Lobe | 7.19 ± 0.22 | |
| Pontine Tegmentum | 7.12 ± 0.28 | |
| Striatum | 6.88 ± 0.25 | |
| Subthalamus | 7.21 ± 0.22 | |
| Temporal Lobe | 7.11 ± 0.24 | |
| Thalamus | 7.04 ± 0.22 | |
| White Matter | 7.61 ± 0.21 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Fbxo22 | CB | Cerebellum | 100 | |
| 100 | | |||
| Fbxo22 | CTX | Cerebral cortex | 100 | |
| 100 | | |||
| Fbxo22 | HIP | Hippocampal region | 100 | |
| 100 | | |||
| Fbxo22 | HPF | Hippocampal formation | 100 | |
| 100 | | |||
| Fbxo22 | HY | Hypothalamus | 100 | |
| 100 | | |||
| Fbxo22 | LSX | Lateral septal complex | 100 | |
| 100 | | |||
| Fbxo22 | MB | Midbrain | 100 | |
| 100 | | |||
| Fbxo22 | MY | Medulla | 100 | |
| 100 | | |||
| Fbxo22 | OLF | Olfactory bulb | 100 | |
| 100 | | |||
| Fbxo22 | P | Pons | 100 | |
| 100 | | |||
| Fbxo22 | PAL | Pallidum | 100 | |
| 100 | | |||
| Fbxo22 | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| Fbxo22 | sAMY | Striatum-like amygdalar nuclei | 100 | |
| 100 | | |||
| Fbxo22 | STR | Striatum | 100 | |
| 100 | | |||
| Fbxo22 | STRd | Striatum dorsal region | 100 | |
| 100 | | |||
| Fbxo22 | STRv | Striatum ventral region | 100 | |
| 100 | | |||
| Fbxo22 | TH | Thalamus | 100 | |
| 100 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00095844 | 20 | 348 | 367 | FFPSVPLFGFFGNGEIGCDR | Peptide Atlas |