AutismKB 2.0

Annotation Detail for FBXO10


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Basic Information Top
Gene Symbol:FBXO10 ( FBX10,FLJ41992,MGC149840,PRMT11 )
Gene Full Name: F-box protein 10
Band: 9p13.2
Quick LinksEntrez ID:26267; OMIM: 609092; Uniprot ID:FBX10_HUMAN; ENSEMBL ID: ENSG00000147912; HGNC ID: 13589
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst3 / 6231948
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult32 / 193912116
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia8 / 9584283
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal64 / 336030719
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer2 / 10268019
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain8 / 11009897
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye5 / 21105423
heart0 / 896260 
intestine4 / 23447217
kidney2 / 2117779
larynx0 / 241450 
liver1 / 2077434
lung7 / 33697420
lymph1 / 4427022
lymph node15 / 91610163
mammary gland1 / 1532716
mouth0 / 670520 
muscle4 / 10771537
nerve0 / 157680 
ovary4 / 10205139
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen4 / 5395274
stomach0 / 966190 
testis5 / 33044215
thymus2 / 8113124
thyroid0 / 474730 
tonsil2 / 16999117
trachea0 / 524130 
umbilical cord0 / 136800 
uterus13 / 23287855
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P35441
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.45 ± 1.21
Basal Forebrain1.78 ± 0.28
Basal Part of Pons1.74 ± 0.54
Cerebellar Cortex1.84 ± 0.81
Cerebellar Nuclei2.14 ± 0.82
Claustrum2.66 ± 0.81
Epithalamus1.44 ± 0.89
Frontal Lobe1.74 ± 0.75
Globus Pallidus2.27 ± 0.7
Hypothalamus1.82 ± 0.7
Insula1.53 ± 0.56
Limbic Lobe1.94 ± 0.78
Mesencephalon1.95 ± 0.72
Myelencephalon1.86 ± 0.78
Occipital Lobe2.06 ± 0.85
Parietal Lobe1.92 ± 0.83
Pontine Tegmentum1.96 ± 0.94
Striatum1.78 ± 0.65
Subthalamus2.05 ± 0.86
Temporal Lobe1.93 ± 0.94
Thalamus1.82 ± 0.73
White Matter2.03 ± 0.66
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fbxo10CBCerebellum7.91
7.72
Fbxo10CTXCerebral cortex25.14
20.01
Fbxo10HIPHippocampal region27.38
37.04
Fbxo10HPFHippocampal formation27.88
31.98
Fbxo10HYHypothalamus68.88
59.69
Fbxo10LSXLateral septal complex33.74
26.34
Fbxo10MBMidbrain26.69
23.83
Fbxo10MYMedulla20.25
19.14
Fbxo10OLFOlfactory bulb16.81
13.76
Fbxo10PPons21.78
20.13
Fbxo10PALPallidum28.69
25.68
Fbxo10RHPRetrohippocampal region29.4
24.58
Fbxo10sAMYStriatum-like amygdalar nuclei65.72
53.85
Fbxo10STRStriatum16.87
12.87
Fbxo10STRdStriatum dorsal region5.17
3.69
Fbxo10STRvStriatum ventral region17.83
11.85
Fbxo10THThalamus18.87
15.8
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
FBX10_HUMAN_13 13 13 25 MILAYLHLPDLGR PRIDE
FBX10_HUMAN_161 18 161 178 LGEVALLASIDQHCSTTR PRIDE
FBX10_HUMAN_419 15 419 433 EAMALANSVQGCLIR PRIDE
FBX10_HUMAN_435 7 435 441 CLFRDGK PRIDE
FBX10_HUMAN_442 10 442 451 GGVFVCSHGR PRIDE
FBX10_HUMAN_461 7 461 467 NLTYAVR PRIDE
FBX10_HUMAN_495 14 495 508 NDIYRCRASGIFLR PRIDE
FBX10_HUMAN_531 10 531 540 SGIVVLGNGK PRIDE
FBX10_HUMAN_576 11 576 586 AAGIAVNENGK PRIDE
FBX10_HUMAN_587 9 587 595 GLITENVIR PRIDE
FBX10_HUMAN_614 19 614 632 SNLICFGYSDGVVVGDEGK PRIDE
FBX10_HUMAN_633 12 633 644 GLIEGNTIYANK PRIDE
FBX10_HUMAN_757 12 757 768 GITVAQSSQPTR PRIDE
FBX10_HUMAN_77 7 77 83 QHYLASK PRIDE
FBX10_HUMAN_824 9 824 832 GSGLQLLPR PRIDE
FBX10_HUMAN_88 15 88 102 NALDLESSICFSLFR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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