AutismKB 2.0

Annotation Detail for FBXO4


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Basic Information Top
Gene Symbol:FBXO4 ( DKFZp547N213,FBX4,FLJ10141 )
Gene Full Name: F-box protein 4
Band: 5p13.1
Quick LinksEntrez ID:26272; OMIM: 609090; Uniprot ID:FBX4_HUMAN; ENSEMBL ID: ENSG00000151876; HGNC ID: 13583
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult34 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor0 / 2638450 
glioma2 / 10688318
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal46 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer2 / 10268019
retinoblastoma4 / 4635686
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone2 / 7165527
bone marrow0 / 488010 
brain12 / 110098910
cervix2 / 4817141
connective tissue3 / 14925520
ear1 / 1621261
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine4 / 23447217
kidney2 / 2117779
larynx3 / 24145124
liver1 / 2077434
lung4 / 33697411
lymph0 / 442700 
lymph node6 / 9161065
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate4 / 18934521
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach9 / 9661993
testis6 / 33044218
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P58815
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.81 ± 0.91
Basal Forebrain2.36 ± 0.22
Basal Part of Pons2.14 ± 0.43
Cerebellar Cortex2.61 ± 0.57
Cerebellar Nuclei2.57 ± 0.72
Claustrum2.87 ± 0.58
Epithalamus1.99 ± 0.7
Frontal Lobe2.32 ± 0.68
Globus Pallidus2.36 ± 0.57
Hypothalamus2.45 ± 0.5
Insula2.61 ± 0.95
Limbic Lobe2.35 ± 0.59
Mesencephalon2.57 ± 0.75
Myelencephalon2.38 ± 0.64
Occipital Lobe2.47 ± 0.83
Parietal Lobe2.22 ± 0.65
Pontine Tegmentum2.38 ± 0.61
Striatum2.1 ± 0.59
Subthalamus2.48 ± 0.59
Temporal Lobe2.4 ± 0.69
Thalamus2.34 ± 0.63
White Matter2.59 ± 0.62
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fbxo4CBCerebellum0.28
0.58
Fbxo4CTXCerebral cortex0.89
1.21
Fbxo4HIPHippocampal region0.96
0.77
Fbxo4HPFHippocampal formation0.63
0.49
Fbxo4HYHypothalamus0.08
0.11
Fbxo4LSXLateral septal complex0.26
0.16
Fbxo4MBMidbrain0.2
0.51
Fbxo4MYMedulla0.03
0.07
Fbxo4OLFOlfactory bulb1.36
2.76
Fbxo4PPons0.09
0.21
Fbxo4PALPallidum0.17
0.26
Fbxo4RHPRetrohippocampal region0.08
0.09
Fbxo4sAMYStriatum-like amygdalar nuclei0.12
0.59
Fbxo4STRStriatum0.14
0.16
Fbxo4STRdStriatum dorsal region0.12
0.11
Fbxo4STRvStriatum ventral region0.22
0.16
Fbxo4THThalamus0.39
0.39
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018