AutismKB 2.0

Annotation Detail for AK5


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Basic Information Top
Gene Symbol:AK5 ( AK6,MGC33326 )
Gene Full Name: adenylate kinase 5
Band: 1p31.1
Quick LinksEntrez ID:26289; OMIM: 608009; Uniprot ID:KAD5_HUMAN; ENSEMBL ID: ENSG00000154027; HGNC ID: 365
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult53 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor19 / 26384572
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal67 / 336030719
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor15 / 125191119
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites4 / 4001599
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow1 / 4880120
brain51 / 110098946
cervix0 / 481710 
connective tissue15 / 149255100
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine2 / 2344728
kidney2 / 2117779
larynx0 / 241450 
liver2 / 2077439
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis5 / 33044215
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219308_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.35
Adipocyte6.85
AdrenalCortex7.95
Adrenalgland6.15
Amygdala1286.75
Appendix12.55
AtrioventricularNode6.35
BDCA4+_DentriticCells6.9
Bonemarrow7.75
BronchialEpithelialCells6.75
CD105+_Endothelial6.95
CD14+_Monocytes7.35
CD19+_BCells(neg._sel.)7.15
CD33+_Myeloid8.55
CD34+8.4
CD4+_Tcells7.15
CD56+_NKCells8.7
CD71+_EarlyErythroid6.45
CD8+_Tcells6.55
CardiacMyocytes15.05
Caudatenucleus153.05
Cerebellum6.35
CerebellumPeduncles9.85
CiliaryGanglion5.75
CingulateCortex355.25
Colorectaladenocarcinoma7.05
DorsalRootGanglion5.7
FetalThyroid6.65
Fetalbrain22.1
Fetalliver6.1
Fetallung5.4
GlobusPallidus189.7
Heart11.9
Hypothalamus130.35
Kidney6.3
Leukemia_chronicMyelogenousK-5626.2
Leukemia_promyelocytic-HL-606.2
Leukemialymphoblastic(MOLT-4)5.4
Liver10.65
Lung7.6
Lymphnode5.75
Lymphoma_burkitts(Daudi)9.15
Lymphoma_burkitts(Raji)10.4
MedullaOblongata194.05
OccipitalLobe362.65
OlfactoryBulb15.35
Ovary4.95
Pancreas5.7
PancreaticIslet7.3
ParietalLobe272.8
Pituitary8.05
Placenta6.95
Pons91.5
PrefrontalCortex923.45
Prostate8.1
Salivarygland5.75
SkeletalMuscle9
Skin6.05
SmoothMuscle8.25
Spinalcord42
SubthalamicNucleus319.6
SuperiorCervicalGanglion9.6
TemporalLobe221.05
Testis5.95
TestisGermCell5.6
TestisIntersitial5.8
TestisLeydigCell7
TestisSeminiferousTubule5.9
Thalamus107.55
Thymus5.35
Thyroid8.5
Tongue7.95
Tonsil6.8
Trachea5.85
TrigeminalGanglion7.95
Uterus5.55
UterusCorpus7.1
WholeBlood7.55
Wholebrain478.8
colon6.95
pineal_day8.6
pineal_night8.46
retina11.25
small_intestine6.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P200015
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala12.26 ± 0.63
Basal Forebrain10.94 ± 0.22
Basal Part of Pons11.69 ± 0.27
Cerebellar Cortex10.4 ± 0.54
Cerebellar Nuclei10.83 ± 0.49
Claustrum12.65 ± 0.67
Epithalamus9.88 ± 1.07
Frontal Lobe11.4 ± 0.57
Globus Pallidus10.95 ± 1.08
Hypothalamus10.47 ± 0.64
Insula11.4 ± 0.31
Limbic Lobe12.14 ± 0.57
Mesencephalon11.05 ± 0.55
Myelencephalon11.28 ± 0.7
Occipital Lobe11.35 ± 0.61
Parietal Lobe11.37 ± 0.68
Pontine Tegmentum11.12 ± 0.56
Striatum10.88 ± 1.16
Subthalamus10.42 ± 0.41
Temporal Lobe11.51 ± 0.44
Thalamus10.91 ± 0.49
White Matter12.34 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ak5CBCerebellum21.2
25.33
Ak5CTXCerebral cortex100
100
Ak5HIPHippocampal region100
100
Ak5HPFHippocampal formation100
100
Ak5HYHypothalamus66.35
56.59
Ak5LSXLateral septal complex66.26
57.62
Ak5MBMidbrain61.34
53.96
Ak5MYMedulla51.99
55.18
Ak5OLFOlfactory bulb90.43
100
Ak5PPons57.07
55.71
Ak5PALPallidum62
55.5
Ak5RHPRetrohippocampal region100
100
Ak5sAMYStriatum-like amygdalar nuclei100
100
Ak5STRStriatum100
81.32
Ak5STRdStriatum dorsal region99.77
79.12
Ak5STRvStriatum ventral region100
88
Ak5THThalamus88.98
90.49
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
KAD5_HUMAN_91 9 91 99 GFLIDGYPR PRIDE
PAp00418750 9 431 439 GFLIDGYPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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