AutismKB 2.0

Annotation Detail for GBP1


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Basic Information Top
Gene Symbol:GBP1 ( - )
Gene Full Name: guanylate binding protein 1, interferon-inducible, 67kDa
Band: 1p22.2
Quick LinksEntrez ID:2633; OMIM: 600411; Uniprot ID:GBP1_HUMAN; ENSEMBL ID: ENSG00000117228; HGNC ID: 4182
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus19 / 56401233
neonate1 / 3109732
infant0 / 236200 
juvenile2 / 5555635
adult140 / 193912172
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor11 / 11424696
esophageal tumor1 / 1729057
gastrointestinal tumor6 / 11936950
germ cell tumor11 / 26384541
glioma4 / 10688337
head and neck tumor4 / 13630229
kidney tumor2 / 6895929
leukemia8 / 9584283
liver tumor8 / 9635983
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia18 / 97250185
normal221 / 336030765
ovarian tumor7 / 7668291
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor15 / 90257166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland4 / 33197120
ascites0 / 400150 
bladder2 / 2975767
blood26 / 123478210
bone4 / 7165555
bone marrow1 / 4880120
brain34 / 110098930
cervix0 / 481710 
connective tissue22 / 149255147
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus1 / 2020949
eye3 / 21105414
heart5 / 8962655
intestine25 / 234472106
kidney16 / 21177775
larynx2 / 2414582
liver24 / 207743115
lung56 / 336974166
lymph0 / 442700 
lymph node8 / 9161087
mammary gland2 / 15327113
mouth0 / 670520 
muscle10 / 10771592
nerve2 / 15768126
ovary7 / 10205168
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx6 / 41328145
pituitary gland0 / 165850 
placenta13 / 28082546
prostate2 / 18934510
salivary gland0 / 201550 
skin7 / 21057433
spleen15 / 53952278
stomach8 / 9661982
testis2 / 3304426
thymus13 / 81131160
thyroid3 / 4747363
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord3 / 13680219
uterus52 / 232878223
vascular7 / 51780135
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202270_at
Cell line Expression level Expression bar
721_B_lymphoblasts17.45
Adipocyte8.9
AdrenalCortex12.85
Adrenalgland8.55
Amygdala7.75
Appendix15.2
AtrioventricularNode8.3
BDCA4+_DentriticCells16.65
Bonemarrow8.35
BronchialEpithelialCells7.55
CD105+_Endothelial7.85
CD14+_Monocytes28.3
CD19+_BCells(neg._sel.)8.2
CD33+_Myeloid30.85
CD34+9.35
CD4+_Tcells71.8
CD56+_NKCells53.05
CD71+_EarlyErythroid7.65
CD8+_Tcells89.65
CardiacMyocytes15.6
Caudatenucleus7.1
Cerebellum6.45
CerebellumPeduncles10
CiliaryGanglion9.4
CingulateCortex8.55
Colorectaladenocarcinoma7.75
DorsalRootGanglion8.1
FetalThyroid11.15
Fetalbrain9.3
Fetalliver7.1
Fetallung20.3
GlobusPallidus6.7
Heart14.55
Hypothalamus8.2
Kidney7.65
Leukemia_chronicMyelogenousK-5626.95
Leukemia_promyelocytic-HL-607.05
Leukemialymphoblastic(MOLT-4)6.2
Liver12.85
Lung8.5
Lymphnode40.4
Lymphoma_burkitts(Daudi)11.65
Lymphoma_burkitts(Raji)12.45
MedullaOblongata7
OccipitalLobe7.05
OlfactoryBulb6.25
Ovary6.3
Pancreas6.9
PancreaticIslet8.8
ParietalLobe9.15
Pituitary9.3
Placenta7.75
Pons8.1
PrefrontalCortex9.2
Prostate9
Salivarygland14.85
SkeletalMuscle13.2
Skin7.5
SmoothMuscle54.85
Spinalcord9.85
SubthalamicNucleus7.65
SuperiorCervicalGanglion11.1
TemporalLobe7.75
Testis6.75
TestisGermCell6.15
TestisIntersitial7
TestisLeydigCell8.65
TestisSeminiferousTubule6.85
Thalamus8.35
Thymus6.1
Thyroid33.2
Tongue9.6
Tonsil12.65
Trachea8.1
TrigeminalGanglion17.9
Uterus50.55
UterusCorpus8.45
WholeBlood196.55
Wholebrain6.1
colon30.75
pineal_day9.68
pineal_night9.46
retina10.1
small_intestine13.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P62890
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.66 ± 1.09
Basal Forebrain2.32 ± 0.32
Basal Part of Pons2.01 ± 0.56
Cerebellar Cortex2.04 ± 0.58
Cerebellar Nuclei2.56 ± 0.66
Claustrum3.08 ± 0.78
Epithalamus3.08 ± 0.47
Frontal Lobe2.26 ± 0.71
Globus Pallidus3.69 ± 0.35
Hypothalamus2.44 ± 0.71
Insula2.18 ± 0.4
Limbic Lobe2.28 ± 0.71
Mesencephalon2.44 ± 0.69
Myelencephalon2.47 ± 0.73
Occipital Lobe2.39 ± 0.84
Parietal Lobe2.3 ± 0.76
Pontine Tegmentum2.43 ± 0.76
Striatum2.92 ± 0.67
Subthalamus2.28 ± 0.63
Temporal Lobe2.25 ± 0.69
Thalamus2.49 ± 0.68
White Matter2.92 ± 0.98
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
GBP1_HUMAN_331 12 331 342 AIAHYEQQMGQK PRIDE
PAp00024507 17 407 423 CSALLQVIFSPLEEEVK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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