AutismKB 2.0

Annotation Detail for GNL3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GNL3 ( C77032,E2IG3,MGC800,NS )
Gene Full Name: guanine nucleotide binding protein-like 3 (nucleolar)
Band: 3p21.1
Quick LinksEntrez ID:26354; OMIM: 608011; Uniprot ID:GNL3_HUMAN; ENSEMBL ID: ENSG00000163938; HGNC ID: 29931
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst9 / 62319144
fetus70 / 564012124
neonate3 / 3109796
infant7 / 23620296
juvenile10 / 55556179
adult235 / 1939121121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor7 / 9417874
cervical tumor4 / 34366116
chondrosarcoma9 / 82823108
colorectal tumor27 / 114246236
esophageal tumor2 / 17290115
gastrointestinal tumor30 / 119369251
germ cell tumor60 / 263845227
glioma7 / 10688365
head and neck tumor8 / 13630258
kidney tumor8 / 68959116
leukemia16 / 95842166
liver tumor21 / 96359217
lung tumor10 / 10312796
lymphoma15 / 71755209
non-neoplasia11 / 97250113
normal382 / 3360307113
ovarian tumor14 / 76682182
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS19 / 125680151
prostate cancer20 / 102680194
retinoblastoma23 / 46356496
skin tumor11 / 12494988
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland5 / 33197150
ascites13 / 40015324
bladder3 / 29757100
blood15 / 123478121
bone10 / 71655139
bone marrow12 / 48801245
brain132 / 1100989119
cervix5 / 48171103
connective tissue19 / 149255127
ear0 / 162120 
embryonic tissue30 / 215722139
esophagus2 / 2020998
eye27 / 211054127
heart7 / 8962678
intestine43 / 234472183
kidney27 / 211777127
larynx3 / 24145124
liver45 / 207743216
lung40 / 336974118
lymph8 / 44270180
lymph node10 / 91610109
mammary gland12 / 15327178
mouth4 / 6705259
muscle9 / 10771583
nerve1 / 1576863
ovary17 / 102051166
pancreas9 / 21481241
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta34 / 280825121
prostate29 / 189345153
salivary gland0 / 201550 
skin24 / 210574113
spleen6 / 53952111
stomach21 / 96619217
testis53 / 330442160
thymus8 / 8113198
thyroid4 / 4747384
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord1 / 1368073
uterus33 / 232878141
vascular16 / 51780308
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217850_at
Cell line Expression level Expression bar
721_B_lymphoblasts1608.75
Adipocyte89.65
AdrenalCortex233.2
Adrenalgland29.6
Amygdala61.4
Appendix21.15
AtrioventricularNode35.4
BDCA4+_DentriticCells635.25
Bonemarrow39.3
BronchialEpithelialCells556.75
CD105+_Endothelial401.35
CD14+_Monocytes109.6
CD19+_BCells(neg._sel.)373.45
CD33+_Myeloid180.65
CD34+878.65
CD4+_Tcells527.6
CD56+_NKCells214.25
CD71+_EarlyErythroid54.25
CD8+_Tcells470.2
CardiacMyocytes255.1
Caudatenucleus30.55
Cerebellum23.5
CerebellumPeduncles49.8
CiliaryGanglion34.6
CingulateCortex66.55
Colorectaladenocarcinoma283.4
DorsalRootGanglion30.65
FetalThyroid61.75
Fetalbrain97.05
Fetalliver135.2
Fetallung149.5
GlobusPallidus33.2
Heart117.5
Hypothalamus116.35
Kidney37.35
Leukemia_chronicMyelogenousK-562492.35
Leukemia_promyelocytic-HL-601019.3
Leukemialymphoblastic(MOLT-4)379.7
Liver44.75
Lung20.1
Lymphnode124.65
Lymphoma_burkitts(Daudi)1043.25
Lymphoma_burkitts(Raji)763.7
MedullaOblongata40
OccipitalLobe47.75
OlfactoryBulb53
Ovary119.25
Pancreas106.45
PancreaticIslet353.2
ParietalLobe47.05
Pituitary153.45
Placenta51.3
Pons47.1
PrefrontalCortex99.65
Prostate119.95
Salivarygland96.95
SkeletalMuscle47.25
Skin52.75
SmoothMuscle284.15
Spinalcord52.25
SubthalamicNucleus41.15
SuperiorCervicalGanglion56.5
TemporalLobe46.4
Testis27.65
TestisGermCell103.9
TestisIntersitial47
TestisLeydigCell60.55
TestisSeminiferousTubule74.05
Thalamus57.75
Thymus42.65
Thyroid103.15
Tongue76.55
Tonsil132.05
Trachea87.05
TrigeminalGanglion25.75
Uterus78.15
UterusCorpus33.95
WholeBlood57.95
Wholebrain30.95
colon189.7
pineal_day139.62
pineal_night156.72
retina59.425
small_intestine175.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P41025
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.07 ± 0.27
Basal Forebrain8.07 ± 0.17
Basal Part of Pons8.6 ± 0.18
Cerebellar Cortex8.19 ± 0.16
Cerebellar Nuclei8.45 ± 0.2
Claustrum8.16 ± 0.33
Epithalamus7.89 ± 0.24
Frontal Lobe8.36 ± 0.26
Globus Pallidus7.73 ± 0.28
Hypothalamus8.37 ± 0.27
Insula8.38 ± 0.22
Limbic Lobe8.17 ± 0.33
Mesencephalon8.17 ± 0.33
Myelencephalon8.17 ± 0.35
Occipital Lobe8.27 ± 0.29
Parietal Lobe8.32 ± 0.36
Pontine Tegmentum8.22 ± 0.26
Striatum7.94 ± 0.36
Subthalamus8.5 ± 0.26
Temporal Lobe8.28 ± 0.24
Thalamus8.33 ± 0.3
White Matter7.74 ± 0.17
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
GNL3_HUMAN_324 24 324 347 SPASIEVVKPMEAASAILSQADAR PRIDE
GNL3_HUMAN_360 12 360 371 NSLEFFTMLAQR PRIDE
PAp00001277 15 146 160 CPQVEEAIVQSGQKK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved