AutismKB 2.0

Annotation Detail for GBX1


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Basic Information Top
Gene Symbol:GBX1 ( - )
Gene Full Name: gastrulation brain homeobox 1
Band: 7q36.1
Quick LinksEntrez ID:2636; OMIM: 603354; Uniprot ID:GBX1_HUMAN; ENSEMBL ID: ENSG00000164900; HGNC ID: 4185
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult0 / 19391210 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal2 / 33603070 
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217011_at
Cell line Expression level Expression bar
721_B_lymphoblasts6
Adipocyte4.95
AdrenalCortex5.65
Adrenalgland4.25
Amygdala5.15
Appendix5.9
AtrioventricularNode3.9
BDCA4+_DentriticCells5.3
Bonemarrow7.4
BronchialEpithelialCells4.85
CD105+_Endothelial5
CD14+_Monocytes5.25
CD19+_BCells(neg._sel.)5.15
CD33+_Myeloid6.35
CD34+6.05
CD4+_Tcells5.6
CD56+_NKCells5.85
CD71+_EarlyErythroid4.75
CD8+_Tcells4.8
CardiacMyocytes6.3
Caudatenucleus4.45
Cerebellum4
CerebellumPeduncles5.75
CiliaryGanglion3.85
CingulateCortex6.2
Colorectaladenocarcinoma5.1
DorsalRootGanglion3.75
FetalThyroid4.85
Fetalbrain4.9
Fetalliver4.3
Fetallung4.15
GlobusPallidus3.8
Heart7.1
Hypothalamus5.35
Kidney3.95
Leukemia_chronicMyelogenousK-5624.8
Leukemia_promyelocytic-HL-604.45
Leukemialymphoblastic(MOLT-4)4.05
Liver6.7
Lung5.4
Lymphnode4.3
Lymphoma_burkitts(Daudi)6.45
Lymphoma_burkitts(Raji)7.2
MedullaOblongata4.5
OccipitalLobe4.5
OlfactoryBulb3.95
Ovary3.4
Pancreas4.8
PancreaticIslet5.35
ParietalLobe5.25
Pituitary8.1
Placenta5.1
Pons6.4
PrefrontalCortex6.1
Prostate5.75
Salivarygland4
SkeletalMuscle6.35
Skin3.75
SmoothMuscle6.25
Spinalcord5.3
SubthalamicNucleus4.6
SuperiorCervicalGanglion6.05
TemporalLobe4.6
Testis4.3
TestisGermCell4.9
TestisIntersitial4.4
TestisLeydigCell5
TestisSeminiferousTubule5.1
Thalamus5.8
Thymus4
Thyroid6.25
Tongue4.8
Tonsil5.05
Trachea4.15
TrigeminalGanglion4.9
Uterus4
UterusCorpus4.65
WholeBlood5.35
Wholebrain4.15
colon5
pineal_day6.16
pineal_night6.02
retina6.125
small_intestine4.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P309069
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.25 ± 1.03
Basal Forebrain1.76 ± 0.2
Basal Part of Pons1.5 ± 0.55
Cerebellar Cortex1.64 ± 0.79
Cerebellar Nuclei2.05 ± 0.76
Claustrum2.65 ± 1.17
Epithalamus1.48 ± 0.73
Frontal Lobe1.61 ± 0.67
Globus Pallidus2.45 ± 0.58
Hypothalamus1.87 ± 0.71
Insula1.68 ± 0.57
Limbic Lobe1.78 ± 0.63
Mesencephalon1.93 ± 0.74
Myelencephalon1.79 ± 0.69
Occipital Lobe1.79 ± 0.6
Parietal Lobe1.76 ± 0.68
Pontine Tegmentum1.75 ± 0.58
Striatum1.92 ± 0.5
Subthalamus1.88 ± 0.64
Temporal Lobe1.65 ± 0.63
Thalamus1.74 ± 0.62
White Matter2.28 ± 0.21
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018