Annotation Detail for SEZ6L2
Basic Information Top
| Gene Symbol: | SEZ6L2 ( FLJ90517,PSK-1 ) |
|---|---|
| Gene Full Name: | seizure related 6 homolog (mouse)-like 2 |
| Band: | 16p11.2 |
| Quick Links | Entrez ID:26470; OMIM: NA; Uniprot ID:SE6L2_HUMAN; ENSEMBL ID: ENSG00000174938; HGNC ID: 30844 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.6314
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 3 / 62319 | 48 | |
| fetus | 29 / 564012 | 51 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 133 / 1939121 | 68 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 5 / 94178 | 53 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 3 / 82823 | 36 | |
| colorectal tumor | 1 / 114246 | 8 |  |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 22 / 263845 | 83 | |
| glioma | 12 / 106883 | 112 | |
| head and neck tumor | 3 / 136302 | 22 | |
| kidney tumor | 6 / 68959 | 87 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 6 / 103127 | 58 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 193 / 3360307 | 57 | |
| ovarian tumor | 13 / 76682 | 169 | |
| pancreatic tumor | 10 / 104616 | 95 | |
| primitive neuroectodermal tumor of the CNS | 18 / 125680 | 143 | |
| prostate cancer | 23 / 102680 | 223 |  |
| retinoblastoma | 6 / 46356 | 129 | |
| skin tumor | 4 / 124949 | 32 | |
| soft tissue/muscle tissue tumor | 3 / 125191 | 23 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 3 / 71655 | 41 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 94 / 1100989 | 85 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 5 / 215722 | 23 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 35 / 211054 | 165 | |
| heart | 3 / 89626 | 33 | |
| intestine | 4 / 234472 | 17 | |
| kidney | 9 / 211777 | 42 | |
| larynx | 1 / 24145 | 41 | |
| liver | 1 / 207743 | 4 | |
| lung | 11 / 336974 | 32 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 9 / 153271 | 58 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 3 / 107715 | 27 | |
| nerve | 3 / 15768 | 190 | |
| ovary | 14 / 102051 | 137 | |
| pancreas | 30 / 214812 | 139 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 8 / 280825 | 28 | |
| prostate | 26 / 189345 | 137 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 5 / 210574 | 23 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 1 / 96619 | 10 | |
| testis | 22 / 330442 | 66 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 2 / 232878 | 8 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 218720_x_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 4.5 | |
| Adipocyte | 3.6 | |
| AdrenalCortex | 3.7 | |
| Adrenalgland | 3.5 | |
| Amygdala | 65.15 | |
| Appendix | 3.6 | |
| AtrioventricularNode | 2.65 | |
| BDCA4+_DentriticCells | 4 | |
| Bonemarrow | 3.55 | |
| BronchialEpithelialCells | 3.55 | |
| CD105+_Endothelial | 3.6 | |
| CD14+_Monocytes | 3.8 | |
| CD19+_BCells(neg._sel.) | 3.8 | |
| CD33+_Myeloid | 4.6 | |
| CD34+ | 4.55 | |
| CD4+_Tcells | 3.9 | |
| CD56+_NKCells | 4.25 | |
| CD71+_EarlyErythroid | 3.35 | |
| CD8+_Tcells | 3.5 | |
| CardiacMyocytes | 4.9 | |
| Caudatenucleus | 4.95 | |
| Cerebellum | 70.45 | |
| CerebellumPeduncles | 40.95 | |
| CiliaryGanglion | 2.45 | |
| CingulateCortex | 14.2 | |
| Colorectaladenocarcinoma | 3.75 | |
| DorsalRootGanglion | 2.7 | |
| FetalThyroid | 3.5 | |
| Fetalbrain | 42.3 | |
| Fetalliver | 3.15 | |
| Fetallung | 3 | |
| GlobusPallidus | 2.7 | |
| Heart | 4.6 | |
| Hypothalamus | 10.15 | |
| Kidney | 2.9 | |
| Leukemia_chronicMyelogenousK-562 | 3.35 | |
| Leukemia_promyelocytic-HL-60 | 3.2 | |
| Leukemialymphoblastic(MOLT-4) | 2.9 | |
| Liver | 4.7 | |
| Lung | 4 | |
| Lymphnode | 3.1 | |
| Lymphoma_burkitts(Daudi) | 4.6 | |
| Lymphoma_burkitts(Raji) | 4.95 | |
| MedullaOblongata | 5.1 | |
| OccipitalLobe | 5.25 | |
| OlfactoryBulb | 2.85 | |
| Ovary | 2.4 | |
| Pancreas | 2.9 | |
| PancreaticIslet | 9.55 | |
| ParietalLobe | 14.3 | |
| Pituitary | 22.8 | |
| Placenta | 3.7 | |
| Pons | 4.8 | |
| PrefrontalCortex | 35.4 | |
| Prostate | 16.75 | |
| Salivarygland | 2.9 | |
| SkeletalMuscle | 4.15 | |
| Skin | 2.7 | |
| SmoothMuscle | 4.35 | |
| Spinalcord | 6.2 | |
| SubthalamicNucleus | 4.25 | |
| SuperiorCervicalGanglion | 4 | |
| TemporalLobe | 9.8 | |
| Testis | 4.15 | |
| TestisGermCell | 3.3 | |
| TestisIntersitial | 3 | |
| TestisLeydigCell | 3.55 | |
| TestisSeminiferousTubule | 3.1 | |
| Thalamus | 5.05 | |
| Thymus | 2.8 | |
| Thyroid | 4.5 | |
| Tongue | 3.5 | |
| Tonsil | 3.5 | |
| Trachea | 3.1 | |
| TrigeminalGanglion | 3.45 | |
| Uterus | 2.95 | |
| UterusCorpus | 3.25 | |
| WholeBlood | 3.95 | |
| Wholebrain | 66.2 | |
| colon | 3.65 | |
| pineal_day | 615.08 | |
| pineal_night | 630.08 | |
| retina | 16.675 | |
| small_intestine | 3.5 | |
- Probe name: A_23_P10194
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 10.74 ± 0.47 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 10.55 ± 0.34 | |
| Basal Part of Pons | 11.88 ± 0.26 | |
| Cerebellar Cortex | 11.38 ± 0.2 | |
| Cerebellar Nuclei | 11.32 ± 0.53 | |
| Claustrum | 11.14 ± 0.37 | |
| Epithalamus | 10.3 ± 0.68 | |
| Frontal Lobe | 11.29 ± 0.39 | |
| Globus Pallidus | 9.58 ± 0.48 | |
| Hypothalamus | 11.45 ± 0.38 | |
| Insula | 11.26 ± 0.18 | |
| Limbic Lobe | 10.93 ± 0.71 | |
| Mesencephalon | 10.77 ± 0.47 | |
| Myelencephalon | 10.93 ± 0.71 | |
| Occipital Lobe | 10.4 ± 0.65 | |
| Parietal Lobe | 11.11 ± 0.47 | |
| Pontine Tegmentum | 10.91 ± 0.36 | |
| Striatum | 10.02 ± 0.63 | |
| Subthalamus | 11.48 ± 0.28 | |
| Temporal Lobe | 11.3 ± 0.38 | |
| Thalamus | 11.04 ± 0.29 | |
| White Matter | 9.69 ± 0.43 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Sez6l2 | CB | Cerebellum | 100 | |
| 100 | | |||
| Sez6l2 | CTX | Cerebral cortex | 100 | |
| 85.49 | | |||
| Sez6l2 | HIP | Hippocampal region | 97.89 | |
| 100 | | |||
| Sez6l2 | HPF | Hippocampal formation | 100 | |
| 100 | | |||
| Sez6l2 | HY | Hypothalamus | 100 | |
| 85.72 | | |||
| Sez6l2 | LSX | Lateral septal complex | 100 | |
| 80.32 | | |||
| Sez6l2 | MB | Midbrain | 100 | |
| 94.44 | | |||
| Sez6l2 | MY | Medulla | 100 | |
| 100 | | |||
| Sez6l2 | OLF | Olfactory bulb | 100 | |
| 95.07 | | |||
| Sez6l2 | P | Pons | 100 | |
| 100 | | |||
| Sez6l2 | PAL | Pallidum | 100 | |
| 91.64 | | |||
| Sez6l2 | RHP | Retrohippocampal region | 100 | |
| 94.89 | | |||
| Sez6l2 | sAMY | Striatum-like amygdalar nuclei | 89.28 | |
| 73.95 | | |||
| Sez6l2 | STR | Striatum | 80.04 | |
| 67.42 | | |||
| Sez6l2 | STRd | Striatum dorsal region | 78.92 | |
| 67.08 | | |||
| Sez6l2 | STRv | Striatum ventral region | 72.24 | |
| 61.29 | | |||
| Sez6l2 | TH | Thalamus | 100 | |
| 84.03 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00137664 | 16 | 647 | 662 | TASDAGFPVGSHVQYR | Peptide Atlas |