AutismKB 2.0

Annotation Detail for NUPR1


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Basic Information Top
Gene Symbol:NUPR1 ( COM1,P8 )
Gene Full Name: nuclear protein, transcriptional regulator, 1
Band: 16p11.2
Quick LinksEntrez ID:26471; OMIM: NA; Uniprot ID:NUPR1_HUMAN; ENSEMBL ID: ENSG00000176046; HGNC ID: 29990
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus30 / 56401253
neonate0 / 310970 
infant4 / 23620169
juvenile0 / 555560 
adult185 / 193912195
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor12 / 94178127
cervical tumor0 / 343660 
chondrosarcoma16 / 82823193
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor15 / 119369125
germ cell tumor5 / 26384518
glioma6 / 10688356
head and neck tumor6 / 13630244
kidney tumor4 / 6895958
leukemia0 / 958420 
liver tumor12 / 96359124
lung tumor5 / 10312748
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal169 / 336030750
ovarian tumor4 / 7668252
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer13 / 102680126
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland2 / 3319760
ascites14 / 40015349
bladder0 / 297570 
blood0 / 1234780 
bone14 / 71655195
bone marrow0 / 488010 
brain16 / 110098914
cervix0 / 481710 
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye17 / 21105480
heart11 / 89626122
intestine11 / 23447246
kidney9 / 21177742
larynx0 / 241450 
liver24 / 207743115
lung59 / 336974175
lymph0 / 442700 
lymph node0 / 916100 
mammary gland15 / 15327197
mouth0 / 670520 
muscle2 / 10771518
nerve3 / 15768190
ovary6 / 10205158
pancreas2 / 2148129
parathyroid13 / 20539632
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta13 / 28082546
prostate32 / 189345169
salivary gland1 / 2015549
skin5 / 21057423
spleen1 / 5395218
stomach0 / 966190 
testis19 / 33044257
thymus0 / 811310 
thyroid6 / 47473126
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus10 / 23287842
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209230_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts13.05
Adipocyte853.3
AdrenalCortex196.8
Adrenalgland186.45
Amygdala34.25
Appendix271.3
AtrioventricularNode86.85
BDCA4+_DentriticCells7.95
Bonemarrow32.35
BronchialEpithelialCells975.3
CD105+_Endothelial23.95
CD14+_Monocytes22.65
CD19+_BCells(neg._sel.)10.5
CD33+_Myeloid13.05
CD34+18
CD4+_Tcells10.6
CD56+_NKCells9.5
CD71+_EarlyErythroid17.7
CD8+_Tcells10.35
CardiacMyocytes388.9
Caudatenucleus60.45
Cerebellum38.35
CerebellumPeduncles76.25
CiliaryGanglion89.8
CingulateCortex33.85
Colorectaladenocarcinoma13.45
DorsalRootGanglion65.25
FetalThyroid247.6
Fetalbrain18.3
Fetalliver90.2
Fetallung82.55
GlobusPallidus39
Heart126.25
Hypothalamus158.8
Kidney57.65
Leukemia_chronicMyelogenousK-56226.7
Leukemia_promyelocytic-HL-6016.8
Leukemialymphoblastic(MOLT-4)14
Liver355.25
Lung339.6
Lymphnode87.45
Lymphoma_burkitts(Daudi)32.85
Lymphoma_burkitts(Raji)16.95
MedullaOblongata44.6
OccipitalLobe17.65
OlfactoryBulb214.4
Ovary126
Pancreas369.2
PancreaticIslet105.95
ParietalLobe29.25
Pituitary83.55
Placenta67.3
Pons43.3
PrefrontalCortex63.05
Prostate596
Salivarygland137.05
SkeletalMuscle78.05
Skin129.1
SmoothMuscle328.5
Spinalcord261.25
SubthalamicNucleus38.3
SuperiorCervicalGanglion82.9
TemporalLobe60.55
Testis117.95
TestisGermCell178.45
TestisIntersitial98.9
TestisLeydigCell89.95
TestisSeminiferousTubule153.35
Thalamus71
Thymus69.45
Thyroid1307.35
Tongue102.9
Tonsil62.5
Trachea209.6
TrigeminalGanglion113
Uterus424.25
UterusCorpus278.4
WholeBlood9.35
Wholebrain24.35
colon198.3
pineal_day84.38
pineal_night55.82
retina499.275
small_intestine55.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13331_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.25 ± 0.98
Basal Forebrain1.82 ± 0.46
Basal Part of Pons1.63 ± 0.6
Cerebellar Cortex1.89 ± 0.75
Cerebellar Nuclei2.11 ± 0.81
Claustrum2.74 ± 0.89
Epithalamus1.59 ± 0.8
Frontal Lobe1.67 ± 0.73
Globus Pallidus2.7 ± 0.6
Hypothalamus1.8 ± 0.67
Insula1.78 ± 0.56
Limbic Lobe1.85 ± 0.71
Mesencephalon1.93 ± 0.71
Myelencephalon1.84 ± 0.74
Occipital Lobe1.95 ± 0.86
Parietal Lobe1.81 ± 0.84
Pontine Tegmentum1.94 ± 0.83
Striatum1.85 ± 0.58
Subthalamus1.95 ± 0.78
Temporal Lobe1.8 ± 0.73
Thalamus1.84 ± 0.62
White Matter2.15 ± 0.19
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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