AutismKB 2.0

Annotation Detail for KAT2A


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Basic Information Top
Gene Symbol:KAT2A ( GCN5,GCN5L2,MGC102791,PCAF-b,hGCN5 )
Gene Full Name: K(lysine) acetyltransferase 2A
Band: 17q21.2
Quick LinksEntrez ID:2648; OMIM: 602301; Uniprot ID:KAT2A_HUMAN; ENSEMBL ID: ENSG00000108773; HGNC ID: 4201
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst9 / 62319144
fetus15 / 56401226
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult113 / 193912158
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor16 / 114246140
esophageal tumor1 / 1729057
gastrointestinal tumor11 / 11936992
germ cell tumor7 / 26384526
glioma15 / 106883140
head and neck tumor4 / 13630229
kidney tumor5 / 6895972
leukemia5 / 9584252
liver tumor6 / 9635962
lung tumor13 / 103127126
lymphoma10 / 71755139
non-neoplasia4 / 9725041
normal115 / 336030734
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer3 / 10268029
retinoblastoma3 / 4635664
skin tumor9 / 12494972
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor13 / 90257144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland3 / 3319790
ascites4 / 4001599
bladder0 / 297570 
blood6 / 12347848
bone3 / 7165541
bone marrow0 / 488010 
brain51 / 110098946
cervix5 / 48171103
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue13 / 21572260
esophagus1 / 2020949
eye8 / 21105437
heart2 / 8962622
intestine22 / 23447293
kidney8 / 21177737
larynx3 / 24145124
liver9 / 20774343
lung19 / 33697456
lymph3 / 4427067
lymph node1 / 9161010
mammary gland4 / 15327126
mouth0 / 670520 
muscle2 / 10771518
nerve1 / 1576863
ovary2 / 10205119
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate8 / 18934542
salivary gland0 / 201550 
skin11 / 21057452
spleen0 / 539520 
stomach10 / 96619103
testis15 / 33044245
thymus0 / 811310 
thyroid3 / 4747363
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus24 / 232878103
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202182_at
Cell line Expression level Expression bar
721_B_lymphoblasts115.1
Adipocyte52.7
AdrenalCortex111
Adrenalgland61.85
Amygdala91.95
Appendix32.35
AtrioventricularNode30.7
BDCA4+_DentriticCells110.85
Bonemarrow54.05
BronchialEpithelialCells37.6
CD105+_Endothelial83.95
CD14+_Monocytes57.2
CD19+_BCells(neg._sel.)147.15
CD33+_Myeloid77.25
CD34+276.55
CD4+_Tcells132.35
CD56+_NKCells87.6
CD71+_EarlyErythroid47
CD8+_Tcells115
CardiacMyocytes44.65
Caudatenucleus88.5
Cerebellum85.45
CerebellumPeduncles98.8
CiliaryGanglion27.15
CingulateCortex125.5
Colorectaladenocarcinoma138.95
DorsalRootGanglion40.75
FetalThyroid93
Fetalbrain107.55
Fetalliver34.8
Fetallung55.4
GlobusPallidus111.3
Heart41.45
Hypothalamus161.2
Kidney29.3
Leukemia_chronicMyelogenousK-56295.55
Leukemia_promyelocytic-HL-60133.9
Leukemialymphoblastic(MOLT-4)150.85
Liver64.15
Lung46.7
Lymphnode111.2
Lymphoma_burkitts(Daudi)122.95
Lymphoma_burkitts(Raji)692.1
MedullaOblongata108.75
OccipitalLobe70.2
OlfactoryBulb159
Ovary19.5
Pancreas50.2
PancreaticIslet43.85
ParietalLobe101.6
Pituitary74.75
Placenta44
Pons61.6
PrefrontalCortex146
Prostate72.85
Salivarygland41.5
SkeletalMuscle64.1
Skin25.2
SmoothMuscle36.9
Spinalcord118.85
SubthalamicNucleus101.3
SuperiorCervicalGanglion29.1
TemporalLobe87.85
Testis36.25
TestisGermCell66.8
TestisIntersitial24.7
TestisLeydigCell38.4
TestisSeminiferousTubule86.7
Thalamus143.9
Thymus32.65
Thyroid60.8
Tongue51.4
Tonsil72.9
Trachea35
TrigeminalGanglion33.2
Uterus109.35
UterusCorpus51.9
WholeBlood27.75
Wholebrain116.15
colon21.75
pineal_day99.28
pineal_night88.32
retina58.175
small_intestine22.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15611_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.69 ± 0.61
Basal Forebrain4.25 ± 0.39
Basal Part of Pons4.55 ± 0.39
Cerebellar Cortex4.34 ± 0.45
Cerebellar Nuclei4.24 ± 0.44
Claustrum5.01 ± 0.6
Epithalamus4.05 ± 0.67
Frontal Lobe4.3 ± 0.47
Globus Pallidus5.09 ± 0.28
Hypothalamus4.05 ± 0.47
Insula4.44 ± 0.38
Limbic Lobe4.55 ± 0.47
Mesencephalon4.34 ± 0.5
Myelencephalon4.42 ± 0.46
Occipital Lobe4.62 ± 0.31
Parietal Lobe4.52 ± 0.44
Pontine Tegmentum4.4 ± 0.6
Striatum4.35 ± 0.47
Subthalamus4.14 ± 0.44
Temporal Lobe4.43 ± 0.45
Thalamus4.59 ± 0.35
White Matter4.79 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gcn5l2CBCerebellum64.78
100
Gcn5l2CTXCerebral cortex100
100
Gcn5l2HIPHippocampal region80.45
100
Gcn5l2HPFHippocampal formation82.13
100
Gcn5l2HYHypothalamus78.35
64.58
Gcn5l2LSXLateral septal complex94.94
74.25
Gcn5l2MBMidbrain70.18
67.67
Gcn5l2MYMedulla47.93
53.51
Gcn5l2OLFOlfactory bulb98.77
100
Gcn5l2PPons53.4
56.32
Gcn5l2PALPallidum72.89
68.42
Gcn5l2RHPRetrohippocampal region86.97
77.17
Gcn5l2sAMYStriatum-like amygdalar nuclei82.34
67.18
Gcn5l2STRStriatum95.29
75.41
Gcn5l2STRdStriatum dorsal region95.39
75.25
Gcn5l2STRvStriatum ventral region100
89.41
Gcn5l2THThalamus82.8
74.24
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00502234 23 149 171 SCEHPLADHVSHLENVSEDEINR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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