AutismKB 2.0

Annotation Detail for CNNM4


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Basic Information Top
Gene Symbol:CNNM4 ( ACDP4,FLJ37746,FLJ42791,KIAA1592 )
Gene Full Name: cyclin M4
Band: 2q11.2
Quick LinksEntrez ID:26504; OMIM: 607805; Uniprot ID:CNNM4_HUMAN; ENSEMBL ID: ENSG00000158158; HGNC ID: 105
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult60 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor8 / 26384530
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal89 / 336030726
ovarian tumor4 / 7668252
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow2 / 4880140
brain18 / 110098916
cervix5 / 48171103
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye13 / 21105461
heart3 / 8962633
intestine7 / 23447229
kidney1 / 2117774
larynx0 / 241450 
liver1 / 2077434
lung5 / 33697414
lymph0 / 442700 
lymph node7 / 9161076
mammary gland7 / 15327145
mouth1 / 6705214
muscle6 / 10771555
nerve0 / 157680 
ovary4 / 10205139
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta14 / 28082549
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach3 / 9661931
testis6 / 33044218
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218900_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.9
Adipocyte5
AdrenalCortex5.5
Adrenalgland4.25
Amygdala5.45
Appendix5.85
AtrioventricularNode3.85
BDCA4+_DentriticCells5.3
Bonemarrow5.2
BronchialEpithelialCells5
CD105+_Endothelial4.95
CD14+_Monocytes5.6
CD19+_BCells(neg._sel.)5.5
CD33+_Myeloid6.55
CD34+6.55
CD4+_Tcells5.25
CD56+_NKCells5.85
CD71+_EarlyErythroid4.5
CD8+_Tcells4.65
CardiacMyocytes7.45
Caudatenucleus4.7
Cerebellum16.4
CerebellumPeduncles7.95
CiliaryGanglion3.85
CingulateCortex5.5
Colorectaladenocarcinoma5.3
DorsalRootGanglion4.1
FetalThyroid5.35
Fetalbrain5.55
Fetalliver4.2
Fetallung4.3
GlobusPallidus3.95
Heart37.5
Hypothalamus5.9
Kidney4.3
Leukemia_chronicMyelogenousK-5624.65
Leukemia_promyelocytic-HL-604.6
Leukemialymphoblastic(MOLT-4)4.05
Liver7.1
Lung5.7
Lymphnode4.35
Lymphoma_burkitts(Daudi)6.4
Lymphoma_burkitts(Raji)7.85
MedullaOblongata4.65
OccipitalLobe4.7
OlfactoryBulb4.1
Ovary3.3
Pancreas4.3
PancreaticIslet6.1
ParietalLobe5.7
Pituitary6.35
Placenta5.3
Pons5.1
PrefrontalCortex6.4
Prostate6.05
Salivarygland4.05
SkeletalMuscle6.7
Skin4.2
SmoothMuscle5.6
Spinalcord5.65
SubthalamicNucleus4.9
SuperiorCervicalGanglion6.4
TemporalLobe4.85
Testis5.75
TestisGermCell4.15
TestisIntersitial4.5
TestisLeydigCell5.3
TestisSeminiferousTubule4.45
Thalamus5.4
Thymus3.9
Thyroid11.45
Tongue5.45
Tonsil4.85
Trachea4.3
TrigeminalGanglion5.55
Uterus4.1
UterusCorpus4.95
WholeBlood5.65
Wholebrain5.5
colon7.6
pineal_day114.84
pineal_night43.14
retina6.35
small_intestine5.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14186_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.08 ± 0.79
Basal Forebrain3.41 ± 0.29
Basal Part of Pons3.81 ± 0.7
Cerebellar Cortex3.88 ± 0.59
Cerebellar Nuclei3.73 ± 0.52
Claustrum4.59 ± 0.92
Epithalamus3.35 ± 0.39
Frontal Lobe3.73 ± 0.67
Globus Pallidus3.76 ± 0.63
Hypothalamus4.05 ± 0.76
Insula3.57 ± 0.4
Limbic Lobe3.87 ± 0.7
Mesencephalon3.8 ± 0.66
Myelencephalon3.87 ± 0.68
Occipital Lobe3.84 ± 0.44
Parietal Lobe3.73 ± 0.71
Pontine Tegmentum3.77 ± 0.7
Striatum3.92 ± 0.8
Subthalamus3.45 ± 0.5
Temporal Lobe3.69 ± 0.61
Thalamus3.9 ± 0.58
White Matter4.23 ± 0.26
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cnnm4CBCerebellum63.9
89.06
Cnnm4CTXCerebral cortex100
100
Cnnm4HIPHippocampal region89.25
100
Cnnm4HPFHippocampal formation100
100
Cnnm4HYHypothalamus26.1
19.64
Cnnm4LSXLateral septal complex49.71
35.27
Cnnm4MBMidbrain45.36
38.55
Cnnm4MYMedulla32.81
31.4
Cnnm4OLFOlfactory bulb100
98.97
Cnnm4PPons34.53
32.66
Cnnm4PALPallidum44.36
35.59
Cnnm4RHPRetrohippocampal region100
100
Cnnm4sAMYStriatum-like amygdalar nuclei78.75
56.84
Cnnm4STRStriatum100
81.79
Cnnm4STRdStriatum dorsal region100
87.45
Cnnm4STRvStriatum ventral region100
88.05
Cnnm4THThalamus64.4
52.06
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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