AutismKB 2.0

Annotation Detail for LATS2


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Basic Information Top
Gene Symbol:LATS2 ( FLJ13161,KPM )
Gene Full Name: LATS, large tumor suppressor, homolog 2 (Drosophila)
Band: 13q12.11
Quick LinksEntrez ID:26524; OMIM: 604861; Uniprot ID:LATS2_HUMAN; ENSEMBL ID: ENSG00000150457; HGNC ID: 6515
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst1 / 6231916
fetus25 / 56401244
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult56 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor3 / 9635931
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal138 / 336030741
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone3 / 7165541
bone marrow4 / 4880181
brain8 / 11009897
cervix0 / 481710 
connective tissue3 / 14925520
ear3 / 16212185
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye4 / 21105418
heart2 / 8962622
intestine8 / 23447234
kidney11 / 21177751
larynx1 / 2414541
liver10 / 20774348
lung12 / 33697435
lymph0 / 442700 
lymph node2 / 9161021
mammary gland3 / 15327119
mouth0 / 670520 
muscle2 / 10771518
nerve1 / 1576863
ovary3 / 10205129
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta14 / 28082549
prostate4 / 18934521
salivary gland0 / 201550 
skin4 / 21057418
spleen2 / 5395237
stomach10 / 96619103
testis17 / 33044251
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular8 / 51780154
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P70002
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.29 ± 0.85
Basal Forebrain3.17 ± 0.56
Basal Part of Pons2.59 ± 0.42
Cerebellar Cortex3.68 ± 0.61
Cerebellar Nuclei3.47 ± 0.74
Claustrum3.48 ± 0.88
Epithalamus3.35 ± 0.6
Frontal Lobe3.26 ± 0.75
Globus Pallidus4.17 ± 0.83
Hypothalamus2.56 ± 0.43
Insula2.97 ± 0.94
Limbic Lobe3.63 ± 1.01
Mesencephalon3.27 ± 0.65
Myelencephalon3.41 ± 0.7
Occipital Lobe3.94 ± 0.86
Parietal Lobe3.17 ± 0.78
Pontine Tegmentum3.68 ± 0.71
Striatum3.65 ± 1.29
Subthalamus3.59 ± 0.6
Temporal Lobe3.16 ± 0.79
Thalamus3.6 ± 0.77
White Matter4.26 ± 0.73
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lats2CBCerebellum25.25
37.76
Lats2CTXCerebral cortex9.64
7.67
Lats2HIPHippocampal region41.15
72.44
Lats2HPFHippocampal formation29.52
44.34
Lats2HYHypothalamus1.77
1.45
Lats2LSXLateral septal complex46.24
48.99
Lats2MBMidbrain5.92
6.71
Lats2MYMedulla7.94
8.8
Lats2OLFOlfactory bulb10.39
9.32
Lats2PPons6.05
6.4
Lats2PALPallidum4.43
4.42
Lats2RHPRetrohippocampal region13.8
12.17
Lats2sAMYStriatum-like amygdalar nuclei2.12
1.83
Lats2STRStriatum8.69
9.42
Lats2STRdStriatum dorsal region4.71
4.45
Lats2STRvStriatum ventral region9.56
12.56
Lats2THThalamus10.57
11.55
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018