AutismKB 2.0

Annotation Detail for AATF


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:AATF ( CHE-1,CHE1,DED )
Gene Full Name: apoptosis antagonizing transcription factor
Band: 17q12
Quick LinksEntrez ID:26574; OMIM: 608463; Uniprot ID:AATF_HUMAN; ENSEMBL ID: ENSG00000108270; HGNC ID: 19235
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus31 / 56401254
neonate0 / 310970 
infant1 / 2362042
juvenile6 / 55556107
adult259 / 1939121133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor11 / 94178116
cervical tumor6 / 34366174
chondrosarcoma5 / 8282360
colorectal tumor9 / 11424678
esophageal tumor2 / 17290115
gastrointestinal tumor9 / 11936975
germ cell tumor21 / 26384579
glioma12 / 106883112
head and neck tumor2 / 13630214
kidney tumor6 / 6895987
leukemia7 / 9584273
liver tumor11 / 96359114
lung tumor11 / 103127106
lymphoma10 / 71755139
non-neoplasia7 / 9725071
normal231 / 336030768
ovarian tumor3 / 7668239
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS16 / 125680127
prostate cancer7 / 10268068
retinoblastoma2 / 4635643
skin tumor20 / 124949160
soft tissue/muscle tissue tumor137 / 1251911094
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites8 / 40015199
bladder2 / 2975767
blood9 / 12347872
bone3 / 7165541
bone marrow2 / 4880140
brain71 / 110098964
cervix10 / 48171207
connective tissue143 / 149255958
ear0 / 162120 
embryonic tissue15 / 21572269
esophagus2 / 2020998
eye18 / 21105485
heart8 / 8962689
intestine18 / 23447276
kidney16 / 21177775
larynx1 / 2414541
liver18 / 20774386
lung23 / 33697468
lymph7 / 44270158
lymph node6 / 9161065
mammary gland13 / 15327184
mouth3 / 6705244
muscle11 / 107715102
nerve0 / 157680 
ovary3 / 10205129
pancreas6 / 21481227
parathyroid1 / 2053948
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta21 / 28082574
prostate10 / 18934552
salivary gland1 / 2015549
skin24 / 210574113
spleen9 / 53952166
stomach4 / 9661941
testis31 / 33044293
thymus6 / 8113173
thyroid1 / 4747321
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord0 / 136800 
uterus12 / 23287851
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209165_at
Cell line Expression level Expression bar
721_B_lymphoblasts209
Adipocyte43.2
AdrenalCortex29.55
Adrenalgland45.4
Amygdala31.05
Appendix10.05
AtrioventricularNode9.7
BDCA4+_DentriticCells151.8
Bonemarrow40.45
BronchialEpithelialCells95.8
CD105+_Endothelial118.05
CD14+_Monocytes169
CD19+_BCells(neg._sel.)185.2
CD33+_Myeloid175.05
CD34+198.45
CD4+_Tcells114.1
CD56+_NKCells261.3
CD71+_EarlyErythroid68.5
CD8+_Tcells102.95
CardiacMyocytes38
Caudatenucleus34.45
Cerebellum44.35
CerebellumPeduncles58.25
CiliaryGanglion8.35
CingulateCortex29.4
Colorectaladenocarcinoma371
DorsalRootGanglion9.75
FetalThyroid59.15
Fetalbrain23.05
Fetalliver35.85
Fetallung23.95
GlobusPallidus10.85
Heart18.95
Hypothalamus59.7
Kidney32.8
Leukemia_chronicMyelogenousK-56298.15
Leukemia_promyelocytic-HL-60105.15
Leukemialymphoblastic(MOLT-4)122.05
Liver39
Lung129.05
Lymphnode33.4
Lymphoma_burkitts(Daudi)261
Lymphoma_burkitts(Raji)159.95
MedullaOblongata22.65
OccipitalLobe22.85
OlfactoryBulb57.5
Ovary13.85
Pancreas82.6
PancreaticIslet58.9
ParietalLobe50.05
Pituitary35.8
Placenta68.45
Pons14.2
PrefrontalCortex49.85
Prostate45.6
Salivarygland27.65
SkeletalMuscle29.35
Skin11.55
SmoothMuscle63.95
Spinalcord44.65
SubthalamicNucleus15.8
SuperiorCervicalGanglion11.2
TemporalLobe12.35
Testis63
TestisGermCell47
TestisIntersitial34.4
TestisLeydigCell36.8
TestisSeminiferousTubule51.1
Thalamus47.1
Thymus81.25
Thyroid85
Tongue19.7
Tonsil74.35
Trachea21.5
TrigeminalGanglion15.8
Uterus83.2
UterusCorpus34.15
WholeBlood93.45
Wholebrain58.15
colon62.5
pineal_day32.12
pineal_night78.78
retina48.675
small_intestine50.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_51_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.61 ± 0.26
Basal Forebrain7.98 ± 0.22
Basal Part of Pons7.98 ± 0.23
Cerebellar Cortex8.04 ± 0.13
Cerebellar Nuclei8.2 ± 0.16
Claustrum7.78 ± 0.21
Epithalamus7.97 ± 0.19
Frontal Lobe7.86 ± 0.25
Globus Pallidus8.4 ± 0.29
Hypothalamus8.04 ± 0.19
Insula7.67 ± 0.17
Limbic Lobe7.68 ± 0.24
Mesencephalon7.95 ± 0.3
Myelencephalon7.89 ± 0.22
Occipital Lobe7.74 ± 0.23
Parietal Lobe7.87 ± 0.27
Pontine Tegmentum7.89 ± 0.25
Striatum8.04 ± 0.36
Subthalamus8.01 ± 0.12
Temporal Lobe7.78 ± 0.21
Thalamus7.96 ± 0.21
White Matter8.78 ± 0.23
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
AATF_HUMAN_198 19 198 216 AGDRNSEDDGVVMTFSSVK PRIDE
AATF_HUMAN_2 17 2 18 AGPQPLALQLEQLLNPR PRIDE
AATF_HUMAN_305 26 305 330 YLVDGTKPNAGSEEISSEDDELVEEK PRIDE
PAp00063657 18 247 264 ALLTTNQLPQPDVFPLFK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved