AutismKB 2.0

Annotation Detail for GPR110


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Basic Information Top
Gene Symbol:GPR110 ( FLJ22684,FLJ30646,KPG_012,MGC125952,PGR19,hGPCR36 )
Gene Full Name: G protein-coupled receptor 110
Band: 6p12.3
Quick LinksEntrez ID:266977; OMIM: NA; Uniprot ID:GP110_HUMAN; ENSEMBL ID: ENSG00000153292; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult22 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor23 / 136302168
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal39 / 336030711
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus1 / 2020949
eye1 / 2110544
heart0 / 896260 
intestine1 / 2344724
kidney21 / 21177799
larynx0 / 241450 
liver0 / 2077430 
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth22 / 67052328
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate5 / 18934526
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach2 / 9661920
testis4 / 33044212
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea22 / 52413419
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220907_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.5
Adipocyte6.55
AdrenalCortex10.45
Adrenalgland6
Amygdala6.65
Appendix15.95
AtrioventricularNode9.1
BDCA4+_DentriticCells6.85
Bonemarrow7.5
BronchialEpithelialCells6.45
CD105+_Endothelial6.6
CD14+_Monocytes7.75
CD19+_BCells(neg._sel.)6.95
CD33+_Myeloid8.2
CD34+8.15
CD4+_Tcells6.9
CD56+_NKCells7.45
CD71+_EarlyErythroid6.5
CD8+_Tcells6.85
CardiacMyocytes15.1
Caudatenucleus6.1
Cerebellum5.6
CerebellumPeduncles8.65
CiliaryGanglion10.9
CingulateCortex7.3
Colorectaladenocarcinoma6.75
DorsalRootGanglion10.4
FetalThyroid9.2
Fetalbrain6.45
Fetalliver6
Fetallung5.15
GlobusPallidus9
Heart10.2
Hypothalamus7
Kidney6.6
Leukemia_chronicMyelogenousK-5625.9
Leukemia_promyelocytic-HL-605.9
Leukemialymphoblastic(MOLT-4)5.15
Liver9.85
Lung7.2
Lymphnode5.55
Lymphoma_burkitts(Daudi)9.25
Lymphoma_burkitts(Raji)10.5
MedullaOblongata6.05
OccipitalLobe6
OlfactoryBulb5.3
Ovary5.65
Pancreas5.65
PancreaticIslet7.4
ParietalLobe8.5
Pituitary8.3
Placenta6.65
Pons12.95
PrefrontalCortex8
Prostate7.45
Salivarygland5.75
SkeletalMuscle15.2
Skin7.1
SmoothMuscle7.95
Spinalcord7.1
SubthalamicNucleus7.1
SuperiorCervicalGanglion12.9
TemporalLobe8.05
Testis5.6
TestisGermCell5.4
TestisIntersitial6.4
TestisLeydigCell7.15
TestisSeminiferousTubule5.8
Thalamus7.5
Thymus5
Thyroid8
Tongue8.85
Tonsil6.85
Trachea5.55
TrigeminalGanglion10.25
Uterus5.25
UterusCorpus6.8
WholeBlood7.05
Wholebrain5.3
colon6.65
pineal_day8.44
pineal_night8.16
retina8.575
small_intestine6.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P214267
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.19 ± 1.05
Basal Forebrain1.69 ± 0.21
Basal Part of Pons1.31 ± 0.29
Cerebellar Cortex1.51 ± 0.73
Cerebellar Nuclei2.05 ± 0.77
Claustrum2.58 ± 1
Epithalamus1.43 ± 0.79
Frontal Lobe1.55 ± 0.7
Globus Pallidus2.37 ± 0.47
Hypothalamus1.74 ± 0.73
Insula1.55 ± 0.51
Limbic Lobe1.68 ± 0.61
Mesencephalon1.88 ± 0.72
Myelencephalon1.74 ± 0.76
Occipital Lobe1.69 ± 0.57
Parietal Lobe1.7 ± 0.73
Pontine Tegmentum1.73 ± 0.65
Striatum1.9 ± 0.57
Subthalamus1.88 ± 0.68
Temporal Lobe1.61 ± 0.71
Thalamus1.67 ± 0.6
White Matter2.32 ± 0.44
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018