AutismKB 2.0

Annotation Detail for GFAP


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Basic Information Top
Gene Symbol:GFAP ( FLJ45472 )
Gene Full Name: glial fibrillary acidic protein
Band: 17q21.31
Quick LinksEntrez ID:2670; OMIM: 137780; Uniprot ID:GFAP_HUMAN; ENSEMBL ID: ENSG00000131095; HGNC ID: 4235
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus64 / 564012113
neonate0 / 310970 
infant12 / 23620508
juvenile2 / 5555635
adult821 / 1939121423
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor16 / 114246140
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor11 / 26384541
glioma521 / 1068834874
head and neck tumor32 / 136302234
kidney tumor60 / 68959870
leukemia19 / 95842198
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia65 / 97250668
normal2087 / 3360307621
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites0 / 400150 
bladder0 / 297570 
blood19 / 123478153
bone0 / 716550 
bone marrow5 / 48801102
brain3264 / 11009892964
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye8 / 21105437
heart0 / 896260 
intestine16 / 23447268
kidney63 / 211777297
larynx32 / 241451325
liver2 / 2077439
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle3 / 10771527
nerve35 / 157682219
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta4 / 28082514
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203540_at
Cell line Expression level Expression bar
721_B_lymphoblasts5
Adipocyte4.05
AdrenalCortex4.6
Adrenalgland3.5
Amygdala6248.45
Appendix4.2
AtrioventricularNode3.25
BDCA4+_DentriticCells4.45
Bonemarrow4.35
BronchialEpithelialCells4.1
CD105+_Endothelial4.1
CD14+_Monocytes4.4
CD19+_BCells(neg._sel.)4.35
CD33+_Myeloid5.2
CD34+5.1
CD4+_Tcells4.45
CD56+_NKCells4.75
CD71+_EarlyErythroid3.9
CD8+_Tcells3.85
CardiacMyocytes5.45
Caudatenucleus3904.95
Cerebellum2282.4
CerebellumPeduncles3405.9
CiliaryGanglion3.25
CingulateCortex2309.7
Colorectaladenocarcinoma4.1
DorsalRootGanglion46.8
FetalThyroid4.05
Fetalbrain1009.55
Fetalliver3.65
Fetallung3.4
GlobusPallidus1274.5
Heart5.4
Hypothalamus10280.25
Kidney3.4
Leukemia_chronicMyelogenousK-5623.95
Leukemia_promyelocytic-HL-603.65
Leukemialymphoblastic(MOLT-4)3.3
Liver5.75
Lung28.95
Lymphnode3.55
Lymphoma_burkitts(Daudi)5.3
Lymphoma_burkitts(Raji)5.85
MedullaOblongata1640.85
OccipitalLobe1513.1
OlfactoryBulb7676.2
Ovary2.85
Pancreas3.3
PancreaticIslet4.35
ParietalLobe2416.15
Pituitary28.1
Placenta4.3
Pons934.4
PrefrontalCortex10289.5
Prostate4.75
Salivarygland3.3
SkeletalMuscle5.15
Skin3.4
SmoothMuscle4.65
Spinalcord19560.35
SubthalamicNucleus1551.3
SuperiorCervicalGanglion69.5
TemporalLobe1148
Testis3.5
TestisGermCell3.5
TestisIntersitial3.5
TestisLeydigCell4.1
TestisSeminiferousTubule3.55
Thalamus8103.45
Thymus3.25
Thyroid5.1
Tongue4.25
Tonsil4
Trachea3.4
TrigeminalGanglion4.4
Uterus3.35
UterusCorpus4
WholeBlood4.45
Wholebrain2287.7
colon4.15
pineal_day4673.92
pineal_night2269.48
retina6607.525
small_intestine3.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P66593
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.84 ± 0.66
Basal Forebrain9.23 ± 0.41
Basal Part of Pons8.24 ± 0.42
Cerebellar Cortex8.29 ± 0.46
Cerebellar Nuclei8.55 ± 1.01
Claustrum7.83 ± 0.45
Epithalamus10.75 ± 0.47
Frontal Lobe8.59 ± 0.88
Globus Pallidus11.46 ± 0.69
Hypothalamus9.39 ± 0.83
Insula8.53 ± 0.39
Limbic Lobe8.42 ± 0.99
Mesencephalon8.9 ± 0.98
Myelencephalon9.01 ± 0.7
Occipital Lobe8.53 ± 0.69
Parietal Lobe8.37 ± 0.91
Pontine Tegmentum8.41 ± 0.8
Striatum8.76 ± 1.21
Subthalamus8.29 ± 1
Temporal Lobe8.3 ± 0.79
Thalamus9 ± 0.64
White Matter10.21 ± 0.99
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
GfapCBCerebellum52.78
52.54
GfapCTXCerebral cortex13.54
11.85
GfapHIPHippocampal region60.05
59.36
GfapHPFHippocampal formation49.38
46.2
GfapHYHypothalamus19.95
18.65
GfapLSXLateral septal complex35.84
31.15
GfapMBMidbrain29.51
36.86
GfapMYMedulla77
78.47
GfapOLFOlfactory bulb56.63
38.34
GfapPPons67.86
75.06
GfapPALPallidum23.94
20.82
GfapRHPRetrohippocampal region30.82
26.84
GfapsAMYStriatum-like amygdalar nuclei23.71
21.52
GfapSTRStriatum18.71
17.61
GfapSTRdStriatum dorsal region17.81
18.56
GfapSTRvStriatum ventral region10.71
6.07
GfapTHThalamus34.5
38.38
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00044639 11 357 367 LALDIEIATYR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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