AutismKB 2.0

Annotation Detail for RPS6KC1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:RPS6KC1 ( RPK118,humS6PKh1 )
Gene Full Name: ribosomal protein S6 kinase, 52kDa, polypeptide 1
Band: 1q32.3
Quick LinksEntrez ID:26750; OMIM: NA; Uniprot ID:KS6C1_HUMAN; ENSEMBL ID: ENSG00000136643; HGNC ID: 10439
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus27 / 56401247
neonate1 / 3109732
infant0 / 236200 
juvenile1 / 5555617
adult63 / 193912132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor8 / 26384530
glioma2 / 10688318
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal113 / 336030733
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma2 / 4635643
skin tumor4 / 12494932
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone5 / 7165569
bone marrow0 / 488010 
brain60 / 110098954
cervix1 / 4817120
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus1 / 2020949
eye6 / 21105428
heart1 / 8962611
intestine2 / 2344728
kidney1 / 2117774
larynx0 / 241450 
liver1 / 2077434
lung9 / 33697426
lymph0 / 442700 
lymph node1 / 9161010
mammary gland7 / 15327145
mouth2 / 6705229
muscle5 / 10771546
nerve1 / 1576863
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate4 / 18934521
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach3 / 9661931
testis24 / 33044272
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus7 / 23287830
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218909_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.1
Adipocyte4.2
AdrenalCortex4.45
Adrenalgland3.5
Amygdala11.45
Appendix4.55
AtrioventricularNode3.2
BDCA4+_DentriticCells5
Bonemarrow4.15
BronchialEpithelialCells4.2
CD105+_Endothelial8.3
CD14+_Monocytes9.45
CD19+_BCells(neg._sel.)4.75
CD33+_Myeloid9.3
CD34+7.25
CD4+_Tcells4.8
CD56+_NKCells9.85
CD71+_EarlyErythroid4.4
CD8+_Tcells4.45
CardiacMyocytes7.5
Caudatenucleus4.6
Cerebellum3.35
CerebellumPeduncles4.75
CiliaryGanglion3.05
CingulateCortex7
Colorectaladenocarcinoma4.2
DorsalRootGanglion3.25
FetalThyroid4.05
Fetalbrain8.6
Fetalliver3.7
Fetallung3.5
GlobusPallidus3.4
Heart5.3
Hypothalamus13.05
Kidney3.4
Leukemia_chronicMyelogenousK-5627.25
Leukemia_promyelocytic-HL-603.65
Leukemialymphoblastic(MOLT-4)3.35
Liver5.55
Lung4.75
Lymphnode3.65
Lymphoma_burkitts(Daudi)5.35
Lymphoma_burkitts(Raji)5.85
MedullaOblongata6.8
OccipitalLobe7.65
OlfactoryBulb3.4
Ovary2.8
Pancreas3.4
PancreaticIslet4.55
ParietalLobe7
Pituitary5
Placenta4.35
Pons4.15
PrefrontalCortex33.95
Prostate5
Salivarygland3.4
SkeletalMuscle5
Skin3.25
SmoothMuscle4.95
Spinalcord8.35
SubthalamicNucleus5.4
SuperiorCervicalGanglion5.1
TemporalLobe3.9
Testis3.75
TestisGermCell21.9
TestisIntersitial27.3
TestisLeydigCell4.8
TestisSeminiferousTubule8.75
Thalamus8.05
Thymus3.3
Thyroid5.4
Tongue4.1
Tonsil4.1
Trachea3.5
TrigeminalGanglion4.45
Uterus4.9
UterusCorpus3.8
WholeBlood4.8
Wholebrain4.5
colon4.2
pineal_day8
pineal_night5.44
retina5.2
small_intestine4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P104109
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.28 ± 0.29
Basal Forebrain8.16 ± 0.07
Basal Part of Pons8.54 ± 0.13
Cerebellar Cortex8.02 ± 0.2
Cerebellar Nuclei8.5 ± 0.25
Claustrum8.1 ± 0.29
Epithalamus8.02 ± 0.26
Frontal Lobe8.37 ± 0.37
Globus Pallidus8.21 ± 0.38
Hypothalamus8.22 ± 0.28
Insula8.21 ± 0.34
Limbic Lobe8.44 ± 0.48
Mesencephalon8.27 ± 0.36
Myelencephalon8.33 ± 0.38
Occipital Lobe8.68 ± 0.27
Parietal Lobe8.49 ± 0.33
Pontine Tegmentum8.34 ± 0.45
Striatum8.52 ± 0.27
Subthalamus8.61 ± 0.04
Temporal Lobe8.34 ± 0.32
Thalamus8.31 ± 0.24
White Matter8.78 ± 0.29
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved