AutismKB 2.0

Annotation Detail for GGT5


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Basic Information Top
Gene Symbol:GGT5 ( DKFZp566O011,FLJ92733,GGT-REL,GGTLA1 )
Gene Full Name: gamma-glutamyltransferase 5
Band: 22q11.23
Quick LinksEntrez ID:2687; OMIM: 137168; Uniprot ID:GGT5_HUMAN; ENSEMBL ID: ENSG00000099998; HGNC ID: 4260
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus17 / 56401230
neonate1 / 3109732
infant0 / 236200 
juvenile2 / 5555635
adult91 / 193912146
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor2 / 2638457
glioma7 / 10688365
head and neck tumor1 / 1363027
kidney tumor4 / 6895958
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia12 / 97250123
normal249 / 336030774
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland17 / 33197512
ascites0 / 400150 
bladder3 / 29757100
blood0 / 1234780 
bone3 / 7165541
bone marrow1 / 4880120
brain69 / 110098962
cervix1 / 4817120
connective tissue14 / 14925593
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus2 / 2020998
eye15 / 21105471
heart4 / 8962644
intestine15 / 23447263
kidney13 / 21177761
larynx0 / 241450 
liver1 / 2077434
lung9 / 33697426
lymph0 / 442700 
lymph node1 / 9161010
mammary gland6 / 15327139
mouth4 / 6705259
muscle0 / 1077150 
nerve1 / 1576863
ovary2 / 10205119
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta20 / 28082571
prostate8 / 18934542
salivary gland0 / 201550 
skin0 / 2105740 
spleen27 / 53952500
stomach10 / 96619103
testis7 / 33044221
thymus9 / 81131110
thyroid3 / 4747363
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord1 / 1368073
uterus24 / 232878103
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205582_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.65
Adipocyte13.8
AdrenalCortex7.5
Adrenalgland8.15
Amygdala5.35
Appendix5.35
AtrioventricularNode4.2
BDCA4+_DentriticCells5.35
Bonemarrow5.35
BronchialEpithelialCells4.9
CD105+_Endothelial5.25
CD14+_Monocytes5.4
CD19+_BCells(neg._sel.)5.45
CD33+_Myeloid6.65
CD34+6.45
CD4+_Tcells5.35
CD56+_NKCells5.3
CD71+_EarlyErythroid4.9
CD8+_Tcells4.3
CardiacMyocytes6.65
Caudatenucleus4.75
Cerebellum4.25
CerebellumPeduncles5.9
CiliaryGanglion3.65
CingulateCortex5.3
Colorectaladenocarcinoma5.15
DorsalRootGanglion4
FetalThyroid11.45
Fetalbrain5.1
Fetalliver4.5
Fetallung5.35
GlobusPallidus3.85
Heart11.8
Hypothalamus5.75
Kidney6.05
Leukemia_chronicMyelogenousK-5624.75
Leukemia_promyelocytic-HL-604.5
Leukemialymphoblastic(MOLT-4)4.25
Liver9.65
Lung5.75
Lymphnode7.25
Lymphoma_burkitts(Daudi)6.65
Lymphoma_burkitts(Raji)7.25
MedullaOblongata4.7
OccipitalLobe4.9
OlfactoryBulb4.2
Ovary3.85
Pancreas4.4
PancreaticIslet5.6
ParietalLobe6.65
Pituitary7.3
Placenta5.3
Pons4.95
PrefrontalCortex6.6
Prostate6.15
Salivarygland4.2
SkeletalMuscle8.5
Skin4.05
SmoothMuscle12.6
Spinalcord5.8
SubthalamicNucleus4.9
SuperiorCervicalGanglion5.95
TemporalLobe4.7
Testis4.5
TestisGermCell4.15
TestisIntersitial4.35
TestisLeydigCell5.15
TestisSeminiferousTubule5.05
Thalamus5.35
Thymus4.25
Thyroid13.6
Tongue5.35
Tonsil5.1
Trachea5.4
TrigeminalGanglion5.15
Uterus4.2
UterusCorpus4.7
WholeBlood5.55
Wholebrain4.4
colon5.25
pineal_day6.04
pineal_night6.26
retina13.875
small_intestine5.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P166376
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.21 ± 0.61
Basal Forebrain3.4 ± 0.49
Basal Part of Pons3.66 ± 0.63
Cerebellar Cortex3.28 ± 0.61
Cerebellar Nuclei4.19 ± 0.58
Claustrum2.98 ± 0.43
Epithalamus3.81 ± 0.92
Frontal Lobe3.63 ± 0.55
Globus Pallidus4.67 ± 0.55
Hypothalamus3.48 ± 0.8
Insula3.52 ± 0.66
Limbic Lobe3.35 ± 0.6
Mesencephalon3.75 ± 0.68
Myelencephalon3.76 ± 0.7
Occipital Lobe3.89 ± 0.75
Parietal Lobe3.54 ± 0.78
Pontine Tegmentum3.73 ± 0.7
Striatum4.48 ± 0.65
Subthalamus3.92 ± 0.97
Temporal Lobe3.52 ± 0.55
Thalamus4.01 ± 0.75
White Matter3.72 ± 0.77
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ggtla1CBCerebellum2.44
2.91
Ggtla1CTXCerebral cortex3.71
2.54
Ggtla1HIPHippocampal region4.87
4.71
Ggtla1HPFHippocampal formation4.07
3.61
Ggtla1HYHypothalamus0.92
0.85
Ggtla1LSXLateral septal complex0
0
Ggtla1MBMidbrain0.51
0.56
Ggtla1MYMedulla2.2
2.15
Ggtla1OLFOlfactory bulb4.17
2.86
Ggtla1PPons1.47
1.67
Ggtla1PALPallidum0.49
0.44
Ggtla1RHPRetrohippocampal region2.8
2.1
Ggtla1sAMYStriatum-like amygdalar nuclei2.37
1.58
Ggtla1STRStriatum1.32
0.99
Ggtla1STRdStriatum dorsal region1.04
0.81
Ggtla1STRvStriatum ventral region2.14
1.56
Ggtla1THThalamus2.44
1.96
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00010176 15 496 510 GCVEYEPNFSQEVQR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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