AutismKB 2.0

Annotation Detail for PABPC1


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Basic Information Top
Gene Symbol:PABPC1 ( PAB1,PABP,PABP1,PABPC2,PABPL1 )
Gene Full Name: poly(A) binding protein, cytoplasmic 1
Band: 8q22.3
Quick LinksEntrez ID:26986; OMIM: 604679; Uniprot ID:PABP1_HUMAN; ENSEMBL ID: ENSG00000070756; HGNC ID: 8554
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body59 / 70761833
blastocyst80 / 623191283
fetus268 / 564012475
neonate32 / 310971029
infant12 / 23620508
juvenile49 / 55556881
adult1435 / 1939121740
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor11 / 12794859
bladder carcinoma48 / 174752746
breast (mammary gland) tumor123 / 941781306
cervical tumor45 / 343661309
chondrosarcoma53 / 82823639
colorectal tumor236 / 1142462065
esophageal tumor11 / 17290636
gastrointestinal tumor178 / 1193691491
germ cell tumor236 / 263845894
glioma49 / 106883458
head and neck tumor175 / 1363021283
kidney tumor45 / 68959652
leukemia75 / 95842782
liver tumor69 / 96359716
lung tumor70 / 103127678
lymphoma82 / 717551142
non-neoplasia34 / 97250349
normal1614 / 3360307480
ovarian tumor49 / 76682639
pancreatic tumor74 / 104616707
primitive neuroectodermal tumor of the CNS73 / 125680580
prostate cancer145 / 1026801412
retinoblastoma64 / 463561380
skin tumor105 / 124949840
soft tissue/muscle tissue tumor88 / 125191702
uterine tumor91 / 902571008
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland18 / 33197542
ascites38 / 40015949
bladder44 / 297571478
blood124 / 1234781004
bone81 / 716551130
bone marrow49 / 488011004
brain331 / 1100989300
cervix45 / 48171934
connective tissue85 / 149255569
ear29 / 162121788
embryonic tissue223 / 2157221033
esophagus11 / 20209544
eye168 / 211054796
heart26 / 89626290
intestine297 / 2344721266
kidney98 / 211777462
larynx72 / 241452981
liver103 / 207743495
lung152 / 336974451
lymph43 / 44270971
lymph node65 / 91610709
mammary gland206 / 1532711344
mouth63 / 67052939
muscle40 / 107715371
nerve7 / 15768443
ovary58 / 102051568
pancreas109 / 214812507
parathyroid3 / 20539146
pharynx42 / 413281016
pituitary gland5 / 16585301
placenta56 / 280825199
prostate154 / 189345813
salivary gland20 / 20155992
skin199 / 210574945
spleen29 / 53952537
stomach142 / 966191469
testis184 / 330442556
thymus47 / 81131579
thyroid37 / 47473779
tonsil22 / 169991294
trachea19 / 52413362
umbilical cord3 / 13680219
uterus161 / 232878691
vascular76 / 517801467
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215157_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts5903.5
Adipocyte3126.6
AdrenalCortex710.05
Adrenalgland335.8
Amygdala326.6
Appendix787.75
AtrioventricularNode278.85
BDCA4+_DentriticCells6143.6
Bonemarrow805.7
BronchialEpithelialCells2864.95
CD105+_Endothelial3081.8
CD14+_Monocytes5790.1
CD19+_BCells(neg._sel.)6301.1
CD33+_Myeloid6038.2
CD34+4634.3
CD4+_Tcells6014.4
CD56+_NKCells4771.15
CD71+_EarlyErythroid2807.4
CD8+_Tcells5330.8
CardiacMyocytes2071.95
Caudatenucleus248.95
Cerebellum436.7
CerebellumPeduncles668.9
CiliaryGanglion328.85
CingulateCortex248.6
Colorectaladenocarcinoma2096.8
DorsalRootGanglion290.65
FetalThyroid1980.95
Fetalbrain1637.75
Fetalliver1379.75
Fetallung1649.1
GlobusPallidus131
Heart195.15
Hypothalamus458.05
Kidney244.25
Leukemia_chronicMyelogenousK-5623375.05
Leukemia_promyelocytic-HL-603528.35
Leukemialymphoblastic(MOLT-4)3396.65
Liver900.65
Lung1321.45
Lymphnode2303.8
Lymphoma_burkitts(Daudi)5949.65
Lymphoma_burkitts(Raji)8024.9
MedullaOblongata229.5
OccipitalLobe319.75
OlfactoryBulb920.3
Ovary1275.65
Pancreas2319.15
PancreaticIslet1524.3
ParietalLobe253.75
Pituitary643.8
Placenta1237.45
Pons211.95
PrefrontalCortex517.65
Prostate2076.1
Salivarygland2590.95
SkeletalMuscle63.15
Skin751.9
SmoothMuscle3066.45
Spinalcord599.35
SubthalamicNucleus219.95
SuperiorCervicalGanglion276.2
TemporalLobe204.55
Testis2014.55
TestisGermCell3820.2
TestisIntersitial4950.95
TestisLeydigCell3953.9
TestisSeminiferousTubule3641.05
Thalamus196.8
Thymus1851.95
Thyroid1165.55
Tongue2146.5
Tonsil3037.75
Trachea1524.3
TrigeminalGanglion433.2
Uterus1518.6
UterusCorpus829.65
WholeBlood3911.9
Wholebrain422.4
colon1427.7
pineal_day862.6
pineal_night679.4
retina758.575
small_intestine1260.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P38136
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala12.54 ± 0.23
Basal Forebrain12.55 ± 0.15
Basal Part of Pons12.23 ± 0.2
Cerebellar Cortex12.32 ± 0.14
Cerebellar Nuclei12.42 ± 0.21
Claustrum12.48 ± 0.23
Epithalamus12.91 ± 0.23
Frontal Lobe12.08 ± 0.22
Globus Pallidus12.99 ± 0.17
Hypothalamus12.21 ± 0.47
Insula12.19 ± 0.17
Limbic Lobe12.24 ± 0.28
Mesencephalon12.37 ± 0.28
Myelencephalon12.27 ± 0.28
Occipital Lobe12.55 ± 0.31
Parietal Lobe12.2 ± 0.26
Pontine Tegmentum12.23 ± 0.3
Striatum12.81 ± 0.3
Subthalamus12.15 ± 0.2
Temporal Lobe12.22 ± 0.22
Thalamus12.1 ± 0.17
White Matter12.76 ± 0.21
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PABP1_HUMAN_113 16 113 128 ALYDTFSAFGNILSCK PRIDE
PABP1_HUMAN_138 15 138 152 GYGFVHFETQEAAER PRIDE
PABP1_HUMAN_158 9 158 166 MNGMLLNDR PRIDE
PABP1_HUMAN_186 10 186 195 AKEFTNVYIK PRIDE
PABP1_HUMAN_197 10 197 206 NFGEDMDDER PRIDE
PABP1_HUMAN_273 6 273 278 QTELKR PRIDE
PABP1_HUMAN_30 11 30 40 FSPAGPILSIR PRIDE
PABP1_HUMAN_312 12 312 323 EFSPFGTITSAK PRIDE
PABP1_HUMAN_349 8 349 356 AVTEMNGR PRIDE
PABP1_HUMAN_356 14 356 369 IVATKPLYVALAQR PRIDE
PABP1_HUMAN_357 14 357 370 IVATKPLYVALAQR PRIDE
PABP1_HUMAN_375 11 375 385 QAHLTNQYMQR PRIDE
PABP1_HUMAN_481 25 481 505 VANTSTQTMGPRPAAAAAAATPAVR PRIDE
PABP1_HUMAN_494 13 494 506 PAAAAAAATPAVR PRIDE
PABP1_HUMAN_566 15 566 580 LFPLIQAMHPTLAGK PRIDE
PABP1_HUMAN_580 24 580 603 ITGMLLEIDNSELLHMLESPESLR PRIDE
PABP1_HUMAN_618 19 618 636 QAKEAAQKAVNSATGVPTV PRIDE
PABP1_HUMAN_67 11 67 77 ALDTMNFDVIK PRIDE
PABP1_HUMAN_68 11 68 78 ALDTMNFDVIK PRIDE
PAp00000578 16 114 129 ALYDTFSAFGNILSCK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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